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Disease on EC 1.20.4.2 - methylarsonate reductase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abortion, Habitual
GSTO1 uncommon genetic variants are associated with recurrent miscarriage risk.
Adenocarcinoma
Association between glutathione S-transferase omega 1 A140D polymorphism in the Turkish population and susceptibility to non-small cell lung cancer.
Adenoma
GSTO polymorphism analysis in thyroid nodules suggest that GSTO1 variants do not influence the risk for malignancy.
Alzheimer Disease
EMK: a novel program for family-based allelic and genotypic association tests on quantitative traits.
GSTO1*E155del polymorphism associated with increased risk for late-onset Alzheimer's disease: association hypothesis for an uncommon genetic variant.
Polymorphisms in glutathione S-transferase omega-1 and AD, vascular dementia, and stroke.
Structure, function and disease relevance of Omega-class glutathione transferases.
Three SNPs in the GSTO1, GSTO2 and PRSS11 genes on chromosome 10 are not associated with age-at-onset of Alzheimer's disease.
Amyotrophic Lateral Sclerosis
Glutathione S-transferase Omega 2 DD genotype is associated with an increased risk of sporadic amyotrophic lateral sclerosis in Chinese men.
Structure, function and disease relevance of Omega-class glutathione transferases.
Asthma
Functional polymorphisms of GSTA1 and GSTO2 genes associated with asthma in Italian children.
GSTA1*-69C/T and GSTO2*N142D as asthma- and allergy-related risk factors in Italian adult patients.
GSTA1, GSTO1 and GSTO2 gene polymorphisms in Italian asthma patients.
Atherosclerosis
Association of the glutathione S-transferase omega-1 Ala140Asp polymorphism with cerebrovascular atherosclerosis and plaque-associated interleukin-1 alpha expression.
Breast Neoplasms
Association of GSTO1 A140D and GSTO2 N142D Gene Variations with Breast Cancer Risk
Effects of glutathione-S-transferase polymorphisms on the risk of breast cancer: A population-based case-control study in Pakistan.
Genetic polymorphisms in Glutathione S-transferase Omega (GSTO) and cancer risk: a meta-analysis of 20 studies.
Glutathione S-transferase omega 1 inhibition activates JNK-mediated apoptotic response in breast cancer stem cells.
Investigating the therapeutic potential and mechanism of curcumin in breast cancer based on RNA sequencing and bioinformatics analysis.
No evidence for glutathione S-transferases GSTA2, GSTM2, GSTO1, GSTO2, and GSTZ1 in breast cancer risk.
Polymorphism of glutathione S-transferase omega gene and risk of cancer.
Polymorphisms of glutathione S-transferase A1 and O1 and breast cancer among postmenopausal Danish women.
Quantification and visualization of glutathione S-transferase omega 1 in cells using inductively coupled plasma mass spectrometry (ICP-MS) and fluorescence microscopy.
Role of glutathione S-transferase omega gene polymorphisms in breast-cancer risk.
Significance of Polymorphisms and Expression of Enzyme-Encoding Genes Related to Glutathione in Hematopoietic Cancers and Solid Tumors.
Structure, function and disease relevance of Omega-class glutathione transferases.
Carcinogenesis
Gene polymorphisms of glutathione S-transferase omega 1 and 2, urinary arsenic methylation profile and urothelial carcinoma.
Genetic polymorphisms in glutathione S-transferase (GST) superfamily and risk of arsenic-induced urothelial carcinoma in residents of Southwestern Taiwan.
Genetic polymorphisms of GSTO2, GSTM1, and GSTT1 and risk of gastric cancer.
Identification of dimethylarsinous and monomethylarsonous acids in human urine of the arsenic-affected areas in West Bengal, India.
Smoking and susceptibility to thyroid cancer: an inverse association with CYP1A1 allelic variants.
Carcinoma
A significantly joint effect between arsenic and occupational exposures and risk genotypes/diplotypes of CYP2E1, GSTO1 and GSTO2 on risk of urothelial carcinoma.
Association between glutathione S-transferase omega 1 A140D polymorphism in the Turkish population and susceptibility to non-small cell lung cancer.
Association of glutathione S-transferase omega gene polymorphisms with progression of head and neck cancer.
Combined effects of GSTO1 and SULT1A1 polymorphisms and cigarette smoking on urothelial carcinoma risk in a Taiwanese population.
Glutathione S-transferase omega 2 regulates cell growth and the expression of E-cadherin via post-transcriptional downregulation of ?-catenin in human esophageal squamous cells.
GSTO polymorphism analysis in thyroid nodules suggest that GSTO1 variants do not influence the risk for malignancy.
GSTO1*CC Genotype (rs4925) Predicts Shorter Survival in Clear Cell Renal Cell Carcinoma Male Patients.
Carcinoma, Hepatocellular
Polymorphism of glutathione S-transferase omega gene and risk of cancer.
Quantification and visualization of glutathione S-transferase omega 1 in cells using inductively coupled plasma mass spectrometry (ICP-MS) and fluorescence microscopy.
Significance of Polymorphisms and Expression of Enzyme-Encoding Genes Related to Glutathione in Hematopoietic Cancers and Solid Tumors.
Carcinoma, Non-Small-Cell Lung
Association between glutathione S-transferase omega 1 A140D polymorphism in the Turkish population and susceptibility to non-small cell lung cancer.
Carcinoma, Papillary
GSTO polymorphism analysis in thyroid nodules suggest that GSTO1 variants do not influence the risk for malignancy.
Carcinoma, Renal Cell
GSTO1*CC Genotype (rs4925) Predicts Shorter Survival in Clear Cell Renal Cell Carcinoma Male Patients.
Carcinoma, Squamous Cell
Association between glutathione S-transferase omega 1 A140D polymorphism in the Turkish population and susceptibility to non-small cell lung cancer.
Association of glutathione S-transferase omega gene polymorphisms with progression of head and neck cancer.
Carotid Artery Diseases
Significantly increased risk of carotid atherosclerosis with arsenic exposure and polymorphisms in arsenic metabolism genes.
Cataract
Association between cataract and genetic polymorphisms of GSTM1, GSTT1, and GSTO2 with respect of work place.
GSTO2 polymorphism Asn142Asp modifies the risk of age-related cataract in smokers and subjects exposed to UV irradiation.
Structure, function and disease relevance of Omega-class glutathione transferases.
Cerebrovascular Disorders
Polymorphisms in glutathione S-transferase omega-1 and AD, vascular dementia, and stroke.
Cholangiocarcinoma
Polymorphism of glutathione S-transferase omega gene and risk of cancer.
Colonic Neoplasms
Expression of CYP and GST in human normal and colon tumor tissues.
Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor.
Colorectal Neoplasms
Association between N142D genetic polymorphism of GSTO2 and susceptibility to colorectal cancer.
Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor.
Polymorphism of glutathione S-transferase omega gene and risk of cancer.
Dementia, Vascular
Association of the glutathione S-transferase omega-1 Ala140Asp polymorphism with cerebrovascular atherosclerosis and plaque-associated interleukin-1 alpha expression.
Esophageal Squamous Cell Carcinoma
Glutathione S-transferase omega 2 regulates cell growth and the expression of E-cadherin via post-transcriptional downregulation of ?-catenin in human esophageal squamous cells.
Essential Hypertension
Lack of Association Between Essential Hypertension and GSTO1 Uncommon Genetic Variants in Italian Patients.
glutathione dehydrogenase (ascorbate) deficiency
Deletion of Glu155 causes a deficiency of glutathione transferase Omega 1-1 but does not alter sensitivity to arsenic trioxide and other cytotoxic drugs.
Goiter
GSTO polymorphism analysis in thyroid nodules suggest that GSTO1 variants do not influence the risk for malignancy.
Graft vs Host Disease
Association of GSTO2 (N142D), GSTT1, and GSTM1 Polymorphisms With Graft-Versus-Host Disease in Allogeneic Hematopoietic Stem Cell Transplant Recipients.
Hematuria
GSTP1 and GSTO1 single nucleotide polymorphisms and the response of bladder cancer patients to intravesical chemotherapy.
Hypersensitivity
GSTA1*-69C/T and GSTO2*N142D as asthma- and allergy-related risk factors in Italian adult patients.
Hypothyroidism
GSTO2*N142D gene polymorphism associated with hypothyroidism in Italian patients.
Infections
Glutathione S-transferase omega gene polymorphism as biomarker for human papilloma virus and cervical cancer in iranian women.
Glutathione-S-transferase omega 1 and nurse cell formation during experimental Trichinella infection.
Kidney Failure, Chronic
Association of GSTO1 and GSTO2 Polymorphism with Risk of End-Stage Renal Disease Development and Patient Survival.
Liver Failure
Glutathione S-transferase Omega 2 Genetic Polymorphism and Risk of Hepatic Failure that Lead to Liver Transplantation in Iranian Population.
Liver Neoplasms
Sex-Biased Molecular Signature for Overall Survival of Liver Cancer Patients.
Lung Neoplasms
Association between glutathione S-transferase omega 1 A140D polymorphism in the Turkish population and susceptibility to non-small cell lung cancer.
Lymphatic Metastasis
Role of glutathione S-transferase omega gene polymorphisms in breast-cancer risk.
Lymphoma, B-Cell
Elimination of the differential chemoresistance between the murine B-cell lymphoma LY-ar and LY-as cell lines after arsenic (As2O3) exposure via the overexpression of gsto1 (p28).
Melanoma
GSTO1 regards as a meritorious regulator in cutaneous malignant melanoma cells.
Metabolic Syndrome
Arsenic methylation, GSTO1 polymorphisms, and metabolic syndrome in an arseniasis endemic area of southwestern Taiwan.
Neoplasm Metastasis
Association of glutathione S-transferase omega gene polymorphisms with progression of head and neck cancer.
Glutathione S-transferase omega 1 inhibition activates JNK-mediated apoptotic response in breast cancer stem cells.
Role of glutathione S-transferase omega gene polymorphisms in breast-cancer risk.
Neoplasms
Activity-based protein profiling reveals GSTO1 as the covalent target of piperlongumine and a promising target for combination therapy for cancer.
Association between N142D genetic polymorphism of GSTO2 and susceptibility to colorectal cancer.
Chemotherapy-Induced Ca
Deletion of Glutathione S-Transferase Omega 1 Activates Type I Interferon Genes and Downregulates Tissue Factor.
Expression of CYP and GST in human normal and colon tumor tissues.
Genetic polymorphisms in glutathione S-transferase (GST) superfamily and risk of arsenic-induced urothelial carcinoma in residents of Southwestern Taiwan.
Genetic polymorphisms in Glutathione S-transferase Omega (GSTO) and cancer risk: a meta-analysis of 20 studies.
Genetic polymorphisms of GSTO2, GSTM1, and GSTT1 and risk of gastric cancer.
Glutathione S-transferase omega 1 inhibition activates JNK-mediated apoptotic response in breast cancer stem cells.
Glutathione S-transferase omega 2 regulates cell growth and the expression of E-cadherin via post-transcriptional downregulation of ?-catenin in human esophageal squamous cells.
GSTO polymorphism analysis in thyroid nodules suggest that GSTO1 variants do not influence the risk for malignancy.
GSTO1*CC Genotype (rs4925) Predicts Shorter Survival in Clear Cell Renal Cell Carcinoma Male Patients.
Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes.
Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor.
Nuclear translocation of glutathione transferase omega is a progression marker in Barrett's esophagus.
Polymorphism of glutathione S-transferase omega gene and risk of cancer.
Polymorphisms of glutathione S-transferase A1 and O1 and breast cancer among postmenopausal Danish women.
Potent and selective inhibitors of glutathione S-transferase omega 1 that impair cancer drug resistance.
Role of glutathione S-transferase omega gene polymorphisms in breast-cancer risk.
Role of glutathione-S-transferase and codon 72 of P53 genotypes in epithelial ovarian cancer patients.
Upregulated glutathione transferase omega-1 correlates with progression of urinary bladder carcinoma.
Obesity
Concomitance of Polymorphisms in Glutathione Transferase Omega Genes Is Associated with Risk of Clear Cell Renal Cell Carcinoma.
Ovarian Neoplasms
Genetic alterations in chromosome 10q24.3 and glutathione S-transferase omega 2 gene polymorphism in ovarian cancer.
Role of glutathione-S-transferase and codon 72 of P53 genotypes in epithelial ovarian cancer patients.
Pancreatic Neoplasms
Comparative proteomic analysis of differentially expressed proteins in human pancreatic cancer tissue.
Integrated phenotypic screening and activity-based protein profiling to reveal potential therapy targets of pancreatic cancer.
Papillomavirus Infections
Glutathione S-transferase omega gene polymorphism as biomarker for human papilloma virus and cervical cancer in iranian women.
Parkinson Disease
Glutathione S-Transferase Omega 1 variation does not influence age at onset of Huntington's disease.
Structure, function and disease relevance of Omega-class glutathione transferases.
Polycystic Ovary Syndrome
Assessment of GSTO1 (A140D) and GSTO2 (N142D) Gene Polymorphisms in Iranian Women with Polycystic Ovarian Syndrome.
Pre-Eclampsia
Bioinformatics identification of potential genes and pathways in preeclampsia based on functional gene set enrichment analyses.
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Childhood Pre-B acute lymphoblastic leukemia and glutathione S-transferase omega 1 and 2 polymorphisms.
Prostatic Neoplasms
Lack of association of GSTT1, GSTM1, GSTO1, GSTP1 and CYP1A1 polymorphisms for susceptibility and outcome in Brazilian prostate cancer patients.
Polymorphisms in Genes Encoding Glutathione Transferase Pi and Glutathione Transferase Omega Influence Prostate Cancer Risk and Prognosis.
Psoriasis
Evaluation of Oxidative Stress via Protein Expression of Glutathion S-Transferase and Cytochrome p450 (CYP450) Isoenzymes in Psoriasis Vulgaris Patients Treated with Methotrexate.
Pulmonary Disease, Chronic Obstructive
Association of glutathione-S-transferase omega haplotypes with susceptibility to chronic obstructive pulmonary disease.
Genetic Variants Associated with the Risk of Chronic Obstructive Pulmonary Disease with and without Lung Cancer.
Structure, function and disease relevance of Omega-class glutathione transferases.
Squamous Cell Carcinoma of Head and Neck
Association of glutathione S-transferase omega gene polymorphisms with progression of head and neck cancer.
Stomach Neoplasms
Genetic polymorphisms of GSTO2, GSTM1, and GSTT1 and risk of gastric cancer.
Stroke
Association analysis of Glutathione S-transferase omega-1 and omega-2 genetic polymorphisms and ischemic stroke risk in a Turkish population.
Polymorphisms in glutathione S-transferase omega-1 and AD, vascular dementia, and stroke.
Thyroid Neoplasms
GSTO polymorphism analysis in thyroid nodules suggest that GSTO1 variants do not influence the risk for malignancy.
Thyroid Nodule
GSTO polymorphism analysis in thyroid nodules suggest that GSTO1 variants do not influence the risk for malignancy.
Urinary Bladder Neoplasms
A case-control study of polymorphisms in xenobiotic and arsenic metabolism genes and arsenic-related bladder cancer in New Hampshire.
GSTO1*C/GSTO2*G haplotype is associated with risk of transitional cell carcinoma of urinary bladder.
GSTP1 and GSTO1 single nucleotide polymorphisms and the response of bladder cancer patients to intravesical chemotherapy.
Uterine Cervical Neoplasms
Glutathione S-transferase omega gene polymorphism as biomarker for human papilloma virus and cervical cancer in iranian women.
Varicocele
Influence of all-trans retinoic acid on sperm metabolism and oxidative stress: Its involvement in the physiopathology of varicocele-associated male infertility.