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Reference on EC 1.2.1.36 - retinal dehydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Moffa, D.J.; Lotspeich, F.J.; Krause, R.F.
Preparation and properties of retinal-oxidizing enzyme from rat intestinal mucosa
J. Biol. Chem.
245
439-447
1970
Rattus norvegicus, Rattus norvegicus Wistar
Manually annotated by BRENDA team
Leo, M.A.; Kim, C.I.; Lowe, N.; Lieber, C.S.
Increased hepatic retinal dehydrogenase activity after phenobarbital and ethanol administration
Biochem. Pharmacol.
38
97-103
1989
Peromyscus maniculatus, Rattus norvegicus, Rattus norvegicus BR
Manually annotated by BRENDA team
el Akawi, Z.; Napoli, J.L.
Rat liver cytosolic retinal dehydrogenase: comparison of 13-cis-, 9-cis-, and all-trans-retinal as substrates and effects of cellular retinoid-binding proteins and retinoic acid on activity
Biochemistry
33
1938-1943
1994
Rattus norvegicus, Rattus norvegicus BR
Manually annotated by BRENDA team
Bhat, P.V.; Samaha, H.
Kinetic properties of the human liver cytosolic aldehyde dehydrogenase for retinal isomers
Biochem. Pharmacol.
57
195-197
1999
Rattus norvegicus
Manually annotated by BRENDA team
Lamb, A.L.; Wang, X.; Napoli, J.L.; Newcomer, M.E.
Purification, crystallization and preliminary X-ray diffraction studies of retinal dehydrogenase type II
Acta Crystallogr. Sect. D
54
639-642
1998
Rattus norvegicus
Manually annotated by BRENDA team
Gagnon, I.; Duester, G.; Bhat, P.V.
Kinetic analysis of mouse retinal dehydrogenase type-2 (RALDH2) for retinal substrates
Biochim. Biophys. Acta
1596
156-162
2002
Mus musculus
Manually annotated by BRENDA team
Bhat, P.V.; Marcinkiewicz, M.; Li, Y.; Mader, S.
Changing patterns of renal retinal dehydrogenase expression parallel nephron development in the rat
J. Histochem. Cytochem.
46
1025-1032
1998
Rattus norvegicus, Rattus norvegicus BR
Manually annotated by BRENDA team
Penzes, P.; Wang, X.; Napoli, J.L.
Enzymic characteristics of retinal dehydrogenase type I expressed in Escherichia coli
Biochim. Biophys. Acta
1342
175-181
1997
Rattus norvegicus
Manually annotated by BRENDA team
Labrecque, J.; Bhat, P.V.; Lacroix, A.
Purification and partial characterization of a rat kidney aldehyde dehydrogenase that oxidizes retinal to retinoic acid
Biochem. Cell Biol.
71
85-89
1993
Rattus norvegicus
Manually annotated by BRENDA team
Graham, C.; Hodin, J.; Wistow, G.
A retinaldehyde dehydrogenase as a structural protein in a mammalian eye lens. Gene recruitment of beta-crystallin
J. Biol. Chem.
271
15623-15628
1996
Galegeeska rufescens
Manually annotated by BRENDA team
Lamb, A.L.; Newcomer, M.E.
The structure of retinal dehydrogenase type II at 2.7 A resolution: implications for retinal specificity
Biochemistry
38
6003-6011
1999
Rattus norvegicus (Q63639)
Manually annotated by BRENDA team
Wang, X.; Penzes, P.; Napoli, J.L.
Cloning of a cDNA encoding an aldehyde dehydrogenase and its expression in Escherichia coli. Recognition of retinal as substrate
J. Biol. Chem.
271
16288-16293
1996
Rattus norvegicus (Q63639)
Manually annotated by BRENDA team
Zhao, D.; McCaffery, P.; Ivins, K.J.; Neve, R.L.; Hogan, P.; Chin, W.W.; Drager, U.C.
Molecular identification of a major retinoic-acid-synthesizing enzyme, a retinaldehyde-specific dehydrogenase
Eur. J. Biochem.
240
15-22
1996
Rattus norvegicus
Manually annotated by BRENDA team
Moore, S.A.; Baker, H.M.; Blythe, T.; Kitson, K.E.; Kitson, T.M.; Baker, E.N.
Sheep liver cytosolic aldehyde dehydrogenase: the structure reveals the basis for the retinal specificity of class 1 aldehyde dehydrogenases
Structure
6
1541-1551
1998
Ovis aries aries
Manually annotated by BRENDA team
Posch, K.C.; Burns, R.D; Napoli, J.L.
Biosynthesis of all-trans-retinoic acid from retinal. Recognition of retinal bound to cellular retinol binding protein (type I) as substrate by a purified cytosolic dehydrogenase
J. Biol. Chem.
267
19676-19682
1992
Rattus norvegicus
Manually annotated by BRENDA team
Mey, J.; Babiuk, R.P.; Clugston, R.; Zhang, W.; Greer, J.J.
Retinal dehydrogenase-2 is inhibited by compounds that induce congenital diaphragmatic hernias in rodents
Am. J. Pathol.
162
673-679
2003
Rattus norvegicus
Manually annotated by BRENDA team
Gagnon, I.; Duester, G.; Bhat, P.V.
Enzymatic characterization of recombinant mouse retinal dehydrogenase type 1
Biochem. Pharmacol.
65
1685-1690
2003
Mus musculus
Manually annotated by BRENDA team
Bateman, O.A.; Purkiss, A.G.; van Montfort, R.; Slingsby, C.; Graham, C.; Wistow, G.
Crystal structure of eta-crystallin: adaptation of a class 1 aldehyde dehydrogenase for a new role in the eye lens
Biochemistry
42
4349-4356
2003
Elephantulus edwardii (Q28399)
Manually annotated by BRENDA team
Duester, G.; Mic, F.A.; Molotkov, A.
Cytosolic retinoid dehydrogenases govern ubiquitous metabolism of retinol to retinaldehyde followed by tissue-specific metabolism to retinoic acid
Chem. Biol. Interact.
143-144
201-210
2003
Mus musculus
Manually annotated by BRENDA team
Yamauchi, K.; Nakajima, J.
Effect of coenzymes and thyroid hormones on the dual activities of Xenopus cytosolic thyroid-hormone-binding protein (xCTBP) with aldehyde dehydrogenase activity
Eur. J. Biochem.
269
2257-2264
2002
Xenopus laevis
Manually annotated by BRENDA team
Maly, I.P.; Crotet, V.; Toranelli, M.
The so-called "testis-specific aldehyde dehydrogenase" corresponds to type 2 retinaldehyde dehydrogenase in the mouse
Histochem. Cell Biol.
119
169-174
2003
Mus musculus
Manually annotated by BRENDA team
Sladek, N.E.
Human aldehyde dehydrogenases: Potential pathological, pharmacological, and toxicological impact
J. Biochem. Mol. Toxicol.
17
7-23
2003
Homo sapiens
Manually annotated by BRENDA team
Montplaisir, V.; Lan, N.C.; Guimond, J.; Savineau, C.; Bhat, P.V.; Mader, S.
Recombinant class I aldehyde dehydrogenases specific for all-trans- or 9-cis-retinal
J. Biol. Chem.
277
17486-17492
2002
Rattus norvegicus
Manually annotated by BRENDA team
Molotkov, A.; Duester, G.
Genetic evidence that retinaldehyde dehydrogenase Raldh1 (Aldh1a1) functions downstream of alcohol dehydrogenase Adh1 in metabolism of retinol to retinoic acid
J. Biol. Chem.
278
36085-36090
2003
Mus musculus
Manually annotated by BRENDA team
Bordelon, T.; Montegudo, S.K.; Pakhomova, S.; Oldham, M.L.; Newcomer, M.E.
A disorder to order transition accompanies catalysis in retinaldehyde dehydrogenase type II
J. Biol. Chem.
279
43085-43091
2004
Mus musculus
Manually annotated by BRENDA team
Moreb, J.S.; Gabr, A.; Vartikar, G.R.; Gowda, S.; Zucali, J.R.; Mohuczy, D.
Retinoic acid down-regulates aldehyde dehydrogenase and increases cytotoxicity of 4-hydroperoxycyclophosphamide and acetaldehyde
J. Pharmacol. Exp. Ther.
312
339-345
2005
Homo sapiens
Manually annotated by BRENDA team
Dupe, V.; Matt, N.; Garnier, J.M.; Chambon, P.; Mark, M.; Ghyselinck, N.B.
A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment
Proc. Natl. Acad. Sci. USA
100
14036-14041
2003
Mus musculus
Manually annotated by BRENDA team
Everts, H.B.; Sundberg, J.P.; Ong, D.E.
Immunolocalization of retinoic acid biosynthesis systems in selected sites in rat
Exp. Cell Res.
308
309-319
2005
Rattus norvegicus
Manually annotated by BRENDA team
Graham, C.E.; Brocklehurst, K.; Pickersgill, R.W.; Warren, M.J.
Characterization of retinaldehyde dehydrogenase 3
Biochem. J.
394
67-75
2006
Mus musculus (Q9JHW9)
Manually annotated by BRENDA team
Fujiwara, K.; Maekawa, F.; Kikuchi, M.; Takigami, S.; Yada, T.; Yashiro, T.
Expression of retinaldehyde dehydrogenase (RALDH)2 and RALDH3 but not RALDH1 in the developing anterior pituitary glands of rats
Cell Tissue Res.
328
129-135
2006
Rattus norvegicus (P51647), Rattus norvegicus (Q63639), Rattus norvegicus (Q8K4D8)
Manually annotated by BRENDA team
Molotkov, A.; Molotkova, N.; Duester, G.
Retinoic acid generated by Raldh2 in mesoderm is required for mouse dorsal endodermal pancreas development
Dev. Dyn.
232
950-957
2005
Mus musculus (Q62148), Mus musculus
Manually annotated by BRENDA team
Vermot, J.; Schuhbaur, B.; Le Mouellic, H.; McCaffery, P.; Garnier, J.M.; Hentsch, D.; Brulet, P.; Niederreither, K.; Chambon, P.; Dolle, P.; Le Roux, I.
Retinaldehyde dehydrogenase 2 and Hoxc8 are required in the murine brachial spinal cord for the specification of Lim1+ motoneurons and the correct distribution of Islet1+ motoneurons
Development
132
1611-1621
2005
Mus musculus (Q62148), Mus musculus
Manually annotated by BRENDA team
Ribes, V.; Wang, Z.; Dolle, P.; Niederreither, K.
Retinaldehyde dehydrogenase 2 (RALDH2)-mediated retinoic acid synthesis regulates early mouse embryonic forebrain development by controlling FGF and sonic hedgehog signaling
Development
133
351-361
2006
Mus musculus (Q62148), Mus musculus
Manually annotated by BRENDA team
Vermot, J.; Messaddeq, N.; Niederreither, K.; Dierich, A.; Dolle, P.
Rescue of morphogenetic defects and of retinoic acid signaling in retinaldehyde dehydrogenase 2 (Raldh2) mouse mutants by chimerism with wild-type cells
Differentiation
74
661-668
2006
Mus musculus (P24549), Mus musculus
Manually annotated by BRENDA team
Huq, M.D.; Tsai, N.P.; Gupta, P.; Wei, L.N.
Regulation of retinal dehydrogenases and retinoic acid synthesis by cholesterol metabolites
EMBO J.
25
3203-3213
2006
Mus musculus
Manually annotated by BRENDA team
Kim, Y.H.; Arnold, A.P.
Distribution and onset of retinaldehyde dehydrogenase (zRalDH) expression in zebra finch brain: lack of sex difference in HVC and RA at early posthatch ages
J. Neurobiol.
65
260-268
2005
Taeniopygia guttata
Manually annotated by BRENDA team
Ruehl, R.; Fritzsche, B.; Vermot, J.; Niederreither, K.; Neumann, U.; Schmidt, A.; Schweigert, F.J.; Dolle, P.
Regulation of expression of the retinoic acid-synthesising enzymes retinaldehyde dehydrogenases in the uteri of ovariectomised mice after treatment with oestrogen, gestagen and their combination
Reprod. Fertil. Dev.
18
339-345
2006
Mus musculus (P24549), Mus musculus (Q62148), Mus musculus
Manually annotated by BRENDA team
Rahman, F.B.; Yamauchi, K.
Uncompetitive inhibition of Xenopus laevis aldehyde dehydrogenase 1A1 by divalent cations
Zool. Sci.
23
239-244
2006
Xenopus laevis
Manually annotated by BRENDA team
Belyaeva, O.V.; Korkina, O.V.; Stetsenko, A.V.; Kedishvili, N.Y.
Human retinol dehydrogenase 13 (RDH13) is a mitochondrial short-chain dehydrogenase/reductase with a retinaldehyde reductase activity
FEBS J.
275
138-147
2008
Homo sapiens
Manually annotated by BRENDA team
Marchitti, S.A.; Deitrich, R.A.; Vasiliou, V.
Neurotoxicity and metabolism of the catecholamine-derived 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde: the role of aldehyde dehydrogenase
Pharmacol. Rev.
59
125-150
2007
Homo sapiens (O94788)
Manually annotated by BRENDA team
Alnouti, Y.; Klaassen, C.D.
Tissue distribution, ontogeny, and regulation of aldehyde dehydrogenase (Aldh) enzymes mRNA by prototypical microsomal enzyme inducers in mice
Toxicol. Sci.
101
51-64
2008
Mus musculus (Q62148)
Manually annotated by BRENDA team
Collard, F.; Vertommen, D.; Fortpied, J.; Duester, G.; Van Schaftingen, E.
Identification of 3-deoxyglucosone dehydrogenase as aldehyde dehydrogenase 1A1 (retinaldehyde dehydrogenase 1)
Biochimie
89
369-373
2007
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Fujiwara, K.; Kikuchi, M.; Takigami, S.; Kouki, T.; Yashiro, T.
Expression of retinaldehyde dehydrogenase 1 in the anterior pituitary glands of adult rats
Cell Tissue Res.
329
321-327
2007
Rattus norvegicus (P51647)
Manually annotated by BRENDA team
Liang, D.; Zhang, M.; Bao, J.; Zhang, L.; Xu, X.; Gao, X.; Zhao, Q.
Expressions of Raldh3 and Raldh4 during zebrafish early development
Gene Expr. Patterns
8
248-253
2008
Danio rerio (A9YD19), Danio rerio (Q0H2G3), Danio rerio
Manually annotated by BRENDA team
Kern, J.; Schrage, K.; Koopmans, G.C.; Joosten, E.A.; McCaffery, P.; Mey, J.
Characterization of retinaldehyde dehydrogenase-2 induction in NG2-positive glia after spinal cord contusion injury
Int. J. Dev. Neurosci.
25
7-16
2007
Rattus norvegicus
Manually annotated by BRENDA team
Golz, S.; Muehleisen, T.; Schulte, D.; Mey, J.
Regulation of RALDH-1, RALDH-3 and CYP26A1 by transcription factors cVax/Vax2 and Tbx5 in the embryonic chick retina
Int. J. Dev. Neurosci.
26
435-445
2008
Gallus gallus (P27463), Gallus gallus (Q9DD46)
Manually annotated by BRENDA team
Shimazaki, Y.; Kuroda, T.
Direct analysis of retinal dehydrogenase activity on an electroblotting membrane following separation by non-denaturing two-dimensional electrophoresis
J. Chromatogr. B
860
180-184
2007
Mus musculus
Manually annotated by BRENDA team
Kurth, I.; Thompson, D.A.; Ruether, K.; Feathers, K.L.; Chrispell, J.D.; Schroth, J.; McHenry, C.L.; Schweizer, M.; Skosyrski, S.; Gal, A.; Huebner, C.A.
Targeted disruption of the murine retinal dehydrogenase gene Rdh12 does not limit visual cycle function
Mol. Cell. Biol.
27
1370-1379
2007
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Sima, A.; Parisotto, M.; Mader, S.; Bhat, P.V.
Kinetic characterization of recombinant mouse retinal dehydrogenase types 3 and 4 for retinal substrates
Biochim. Biophys. Acta
1790
1660-1664
2009
Mus musculus, Mus musculus (Q9JHW9)
Manually annotated by BRENDA team
Ahrendt, M.; Hammerschmidt, S.I.; Pabst, O.; Pabst, R.; Bode, U.
Stromal cells confer lymph node-specific properties by shaping a unique microenvironment influencing local immune responses
J. Immunol.
181
1898-1907
2008
Rattus norvegicus
Manually annotated by BRENDA team
Huang, J.; Bi, Y.; Zhu, G.H.; He, Y.; Su, Y.; He, B.C.; Wang, Y.; Kang, Q.; Chen, L.; Zuo, G.W.; Luo, Q.; Shi, Q.; Zhang, B.Q.; Huang, A.; Zhou, L.; Feng, T.; Luu, H.H.; Haydon, R.C.; He, T.C.; Tang, N.
Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells
Liver Int.
29
1569-1581
2009
Mus musculus
Manually annotated by BRENDA team
Goswami, S.; Angkasekwinai, P.; Shan, M.; Greenlee, K.J.; Barranco, W.T.; Polikepahad, S.; Seryshev, A.; Song, L.Z.; Redding, D.; Singh, B.; Sur, S.; Woodruff, P.; Dong, C.; Corry, D.B.; Kheradmand, F.
Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma
Nat. Immunol.
10
496-503
2009
Mus musculus (P24549)
Manually annotated by BRENDA team
Elizondo, G.; Medina-Diaz, I.M.; Cruz, R.; Gonzalez, F.J.; Vega, L.
Retinoic acid modulates retinaldehyde dehydrogenase 1 gene expression through the induction of GADD153-C/EBPbeta interaction
Biochem. Pharmacol.
77
248-257
2009
Mus musculus
Manually annotated by BRENDA team
Kot-Leibovich, H.; Fainsod, A.
Ethanol induces embryonic malformations by competing for retinaldehyde dehydrogenase activity during vertebrate gastrulation
Dis. Model. Mech.
2
295-305
2009
Xenopus laevis
Manually annotated by BRENDA team
Fujiwara, K.; Kikuchi, M.; Horiguchi, K.; Kusumoto, K.; Kouki, T.; Kawanishi, K.; Yashiro, T.
Estrogen receptor alpha regulates retinaldehyde dehydrogenase 1 expression in rat anterior pituitary cells
Endocr. J.
56
963-973
2009
Rattus norvegicus (P51647)
Manually annotated by BRENDA team
Kirschner, R.D.; Rother, K.; Mueller, G.A.; Engeland, K.
The retinal dehydrogenase/reductase retSDR1/DHRS3 gene is activated by p53 and p63 but not by mutants derived from tumors or EEC/ADULT malformation syndromes
Cell Cycle
9
2177-2188
2010
Homo sapiens
Manually annotated by BRENDA team
Bchini, R.; Vasiliou, V.; Branlant, G.; Talfournier, F.; Rahuel-Clermont, S.
Retinoic acid biosynthesis catalyzed by retinal dehydrogenases relies on a rate-limiting conformational transition associated with substrate recognition
Chem. Biol. Interact.
202
78-84
2013
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Wang, C.; Kane, M.A.; Napoli, J.L.
Multiple retinol and retinal dehydrogenases catalyze all-trans-retinoic acid biosynthesis in astrocytes
J. Biol. Chem.
286
6542-6553
2011
Rattus norvegicus
Manually annotated by BRENDA team
Bchini, R.; Vasiliou, V.; Branlant, G.; Talfournier, F.; Rahuel-Clermont, S.
Retinoic acid biosynthesis catalyzed by retinal dehydrogenases relies on a rate-limiting conformational transition associated with substrate recognition
Chem. Biol. Interact.
202
78-84
2013
Homo sapiens (P00352), Homo sapiens, Rattus norvegicus (Q63639)
Manually annotated by BRENDA team
Zhang, M.; Liu, C.; Hu, M.Y.; Zhang, J.; Xu, P.; Li, F.; Zhong, Z.Y.; Liu, L.; Liu, X.D.
High-fat diet enhanced retinal dehydrogenase activity, but suppressed retinol dehydrogenase activity in liver of rats
J. Pharmacol. Sci.
127
430-438
2015
Rattus norvegicus (P51647), Rattus norvegicus Sprague-Dawley (P51647)
Manually annotated by BRENDA team
Ito, K.; Zolfaghari, R.; Hao, L.; Ross, A.C.
Inflammation rapidly modulates the expression of ALDH1A1 (RALDH1) and vimentin in the liver and hepatic macrophages of rats in vivo
Nutr. Metab.
11
54
2014
Rattus norvegicus (P51647)
Manually annotated by BRENDA team
Ohoka, Y.; Yokota-Nakatsuma, A.; Maeda, N.; Takeuchi, H.; Iwata, M.
Retinoic acid and GM-CSF coordinately induce retinal dehydrogenase 2 (RALDH2) expression through cooperation between the RAR/RXR complex and Sp1 in dendritic cells
PLoS ONE
9
e96512
2014
Mus musculus (Q62148), Mus musculus, Mus musculus B10.D2 mice and C57BL/6 mice (Q62148)
Manually annotated by BRENDA team
Xu, J.; Zhang, M.; Zhang, X.; Yang, H.; Sun, B.; Wang, Z.; Zhou, Y.; Wang, S.; Liu, X.; Liu, L.
Contribution of hepatic retinaldehyde dehydrogenase induction to impairment of glucose metabolism by high-fat-diet feeding in C57BL/6J mice
Basic Clin. Pharmacol. Toxicol.
123
539-548
2018
Mus musculus
Manually annotated by BRENDA team
Ma, Z.; Jiang, L.; Li, G.; Liang, D.; Li, L.; Liu, L.; Jiang, C.
Design, synthesis of 1,3-dimethylpyrimidine-2,4-diones as potent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with glucose consumption improving activity
Bioorg. Chem.
101
103971
2020
Homo sapiens (O94788), Homo sapiens (P00352), Homo sapiens (P47895)
Manually annotated by BRENDA team
Harper, A.R.; Le, A.T.; Mather, T.; Burgett, A.; Berry, W.; Summers, J.A.
Design, synthesis, and ex vivo evaluation of a selective inhibitor for retinaldehyde dehydrogenase enzymes
Bioorg. Med. Chem.
26
5766-5779
2018
Gallus gallus, Gallus gallus (O93344), Gallus gallus (P27463), Homo sapiens (O94788)
Manually annotated by BRENDA team
Bui, T.B.C.; Nosaki, S.; Kokawa, M.; Xu, Y.; Kitamura, Y.; Tanokura, M.; Hachimura, S.; Miyakawa, T.
Evaluation of spice and herb as phyto-derived selective modulators of human retinaldehyde dehydrogenases using a simple in vitro method
Biosci. Rep.
41
BSR20210491
2021
Homo sapiens (O94788), Homo sapiens (P00352), Homo sapiens (P47895), Homo sapiens
Manually annotated by BRENDA team
Jimenez, R.; Pequerul, R.; Amor, A.; Lorenzo, J.; Metwally, K.; Aviles, F.X.; Pares, X.; Farres, J.
Inhibitors of aldehyde dehydrogenases of the 1A subfamily as putative anticancer agents kinetic characterization and effect on human cancer cells
Chem. Biol. Interact.
306
123-130
2019
Homo sapiens (O94788), Homo sapiens (P00352), Homo sapiens (P47895)
Manually annotated by BRENDA team
Farazuddin, M.; Goel, R.R.; Kline, N.J.; Landers, J.J.; O'Konek, J.J.; Baker, J.R.
Nanoemulsion adjuvant augments retinaldehyde dehydrogenase activity in dendritic cells via MyD88 pathway
Front. Immunol.
10
916
2019
Mus musculus
Manually annotated by BRENDA team
Jung, K.; Hong, S.H.; Ngo, H.P.; Ho, T.H.; Ahn, Y.J.; Oh, D.K.; Kang, L.W.
Crystal structures of an atypical aldehyde dehydrogenase having bidirectional oxidizing and reducing activities
Int. J. Biol. Macromol.
105
816-824
2017
Bacillus cereus (A0A150BLG9)
Manually annotated by BRENDA team
Hu, H.; Xu, L.; Luo, S.J.; Xiang, T.; Chen, Y.; Cao, Z.R.; Zhang, Y.J.; Mo, Z.; Wang, Y.; Meng, D.F.; Yu, L.; Lin, L.Z.; Zhang, S.J.
Retinal dehydrogenase 5 (RHD5) attenuates metastasis via regulating HIPPO/YAP signaling pathway in hepatocellular carcinoma
Int. J. Med. Sci.
17
1897-1908
2020
Homo sapiens
Manually annotated by BRENDA team
Thangavelu, G.; Lee, Y.C.; Loschi, M.; Schaechter, K.M.; Feser, C.J.; Koehn, B.H.; Nowak, E.C.; Zeiser, R.; Serody, J.S.; Murphy, W.J.; Munn, D.H.; Chambon, P.; Noelle, R.J.; Blazar, B.R.
Dendritic cell expression of retinal aldehyde dehydrogenase-2 controls graft-versus-host disease lethality
J. Immunol.
202
2795-2805
2019
Mus musculus
Manually annotated by BRENDA team
Buchman, C.D.; Hurley, T.D.
Inhibition of the aldehyde dehydrogenase 1/2 family by psoralen and coumarin derivatives
J. Med. Chem.
60
2439-2455
2017
Homo sapiens (O94788), Homo sapiens (P00352), Homo sapiens (P47895)
Manually annotated by BRENDA team
Wang, B.; Chen, X.; Wang, Z.; Xiong, W.; Xu, T.; Zhao, X.; Cao, Y.; Guo, Y.; Li, L.; Chen, S.; Huang, S.; Wang, X.; Fang, M.; Shen, Z.
Aldehyde dehydrogenase 1A1 increases NADH levels and promotes tumor growth via glutathione/dihydrolipoic acid-dependent NAD+ reduction
Oncotarget
8
67043-67055
2017
Homo sapiens (P00352)
Manually annotated by BRENDA team
Park, J.W.; Jung, K.H.; Lee, J.H.; Moon, S.H.; Cho, Y.S.; Lee, K.H.
Inhibition of aldehyde dehydrogenase 1 enhances the cytotoxic effect of retinaldehyde on A549 cancer cells
Oncotarget
8
99382-99393
2017
Homo sapiens
Manually annotated by BRENDA team
Dominguez, M.; Pequerul, R.; Alvarez, R.; Gimenez-Dejoz, J.; Birta, E.; Porte, S.; Ruehl, R.; Pares, X.; Farres, J.; de Lera, A.
Synthesis of apocarotenoids by acyclic cross metathesis and characterization as substrates for human retinaldehyde dehydrogenases
Tetrahedron
74
2567-2574
2018
Homo sapiens (O94788), Homo sapiens (P00352), Homo sapiens (P47895)
-
Manually annotated by BRENDA team