Reference on EC 1.14.19.41 - sterol 22-desaturase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Lamb, D.C.; Maspahy, S.; Kelly, D.E.; Manning, N.J.; Geber, A.; Bennett, J.E.; Kelly, S.L.
Purification, reconstitution, and inhibition of cytochrome P-450 sterol DELTA22-desaturase from the pathogenic fungus Candida glabrata
Antimicrob. Agents Chemother.
43
1725-1728
1999
[Candida] glabrata, [Candida] glabrata L5DU61
Martel, C.M.; Parker, J.E.; Bader, O.; Weig, M.; Gross, U.; Warrilow, A.G.; Kelly, D.E.; Kelly, S.L.
A clinical isolate of Candida albicans with mutations in ERG11 (encoding sterol 14alpha-demethylase) and ERG5 (encoding C22 desaturase) is cross resistant to azoles and amphotericin B
Antimicrob. Agents Chemother.
54
3578-3583
2010
Candida albicans
Giner, J.L.; Djerassi, C.
Inhibition and substrate specificity of yeast DELTA22-desaturase
Biochem. Biophys. Res. Commun.
173
60-66
1990
Saccharomyces cerevisiae
Morikawa, T.; Mizutani, M.; Ohta, D.
Cytochrome P450 subfamily CYP710A genes encode sterol C-22 desaturase in plants
Biochem. Soc. Trans.
34
1202-1205
2006
Arabidopsis thaliana (O64697), Arabidopsis thaliana (O64698)
Kelly, S.L.; Lamb, D.C.; Corran, A.J.; Baldwin, B.C.; Parks, L.W.; Kelly, D.E.
Purification and reconstitution of activity of Saccharomyces cerevisiae P450 61, a sterol DELTA22-desaturase
FEBS Lett.
377
217-220
1995
Saccharomyces cerevisiae, Saccharomyces cerevisiae DK2
Kelly, S.L.; Lamb, D.C.; Kelly, D.E.
Sterol 22-desaturase, cytochrome P45061, possesses activity in xenobiotic metabolism
FEBS Lett.
412
233-235
1997
Saccharomyces cerevisiae (P54781), Saccharomyces cerevisiae
Sun, X.; Wang, W.; Wang, K.; Yu, X.; Liu, J.; Zhou, F.; Xie, B.; Li, S.
Sterol C-22 desaturase ERG5 mediates the sensitivity to antifungal azoles in Neurospora crassa and Fusarium verticillioides
Front. Microbiol.
4
127
2013
Fusarium verticillioides, Neurospora crassa
Skaggs, B.A.; Alexander, J.F.; Pierson, C.A.; Schweitzer, K.S.; Chun, K.T.; Koegel, C.; Barbuch, R.; Bard, M.
Cloning and characterization of the Saccharomyces cerevisiae C-22 sterol desaturase gene, encoding a second cytochrome P-450 involved in ergosterol biosynthesis
Gene
169
105-109
1996
Saccharomyces cerevisiae
Whitaker, B.D.; Gapper, N.E.
Ripening-specific stigmasterol increase in tomato fruit is associated with increased sterol C-22 desaturase (CYP710A11) gene expression
J. Agric. Food Chem.
56
3828-3835
2008
Solanum lycopersicum
Kelly S.L, K.S.; Lamb D.C, L.D.; Baldwin B.C, B.B.; Corran A.J, C.A.; Kelly D.E, K.D.
Characterization of Saccharomyces cerevisiae CTP61, sterol DELTA22-desaturase, and inhibition by azole antifungal agents
J. Biol. Chem.
272
9986-9988
1997
Saccharomyces cerevisiae, Saccharomyces cerevisiae DK2
Morikawa, T.; Mizutani, M.; Aoki, N.; Watanabe, B.; Saga, H.; Saito, S.; Oikawa, A.; Suzuki, H.; Sakurai, N.; Shibata, D.; Wadano, A.; Sakata, K.; Ohta, D.
Cytochrome P450 CYP710A encodes the sterol C-22 desaturase in Arabidopsis and tomato
Plant Cell
18
1008-1022
2006
Arabidopsis thaliana, Solanum lycopersicum (Q1T7C2), Solanum lycopersicum
Arnqvist, L.; Persson, M.; Jonsson, L.; Dutta, P.C.; Sitbon, F.
Overexpression of CYP710A1 and CYP710A4 in transgenic Arabidopsis plants increases the level of stigmasterol at the expense of sitosterol
Planta
227
309-317
2008
Arabidopsis thaliana (O64697), Arabidopsis thaliana (Q9ZV28), Arabidopsis thaliana
Morikawa, T.; Saga, H.; Hashizume, H.; Ohta, D.
CYP710A genes encoding sterol C22-desaturase in Physcomitrella patens as molecular evidence for the evolutionary conservation of a sterol biosynthetic pathway in plants
Planta
229
1311-1322
2009
Physcomitrium patens
Valitova, J.N.; Sulkarnayeva, A.G.; Minibayeva, F.V.
Plant Sterols Diversity, Biosynthesis, and Physiological Functions
Biochemistry (Moscow)
81
819-834
2016
Saccharomyces cerevisiae
Zhang, J.; Li, X.; Lu, F.; Wang, S.; An, Y.; Su, X.; Li, X.; Ma, L.; Han, G.
De novo sequencing and transcriptome analysis reveal key genes regulating steroid metabolism in leaves, roots, adventitious roots and calli of Periploca sepium Bunge
Front. Plant sci.
8
594
2017
Periploca sepium, Periploca sepium Bunge
Mueller, C.; Binder, U.; Maurer, E.; Grimm, C.; Giera, M.; Bracher, F.
Fungal sterol C22-desaturase is not an antimycotic target as shown by selective inhibitors and testing on clinical isolates
Steroids
101
1-6
2015
Saccharomyces cerevisiae, Yarrowia lipolytica, [Candida] glabrata (Q56J92), [Candida] glabrata, [Candida] glabrata NCCLS 84 (Q56J92), Saccharomyces cerevisiae ATCC 9763, Yarrowia lipolytica UCDFST 60-26
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