Reference on EC 1.14.18.1 - tyrosinase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Mayer, A.M.
Polyphenol oxidases in plants - recent progress
Phytochemistry
26
11-20
1987
Vicia faba
-
Mayer, A.M.; Harel, E.
Polyphenol oxidases in plants
Phytochemistry
18
193-215
1979
Vicia faba, Mushroom, Neurospora crassa
-
Palmieri, G.; Giardina, P.; Marzullo, L.; Desiderio, B.; Nitti, G.; Cannio, R.; Sannia, G.
Stability and activity of a phenol oxidase from the ligninolytic fungus Pleurotus ostreatus
Appl. Microbiol. Biotechnol.
39
632-636
1993
Pleurotus ostreatus
Gerdemann, C.; Eicken, C.; Krebs, B.
The crystal structure of catechol oxidase: New insight into the function of type-3 copper proteins
Acc. Chem. Res.
35
183-191
2002
insecta, Mammalia, Streptomyces antibioticus
Janovitz-Klapp, A.; Richard, F.; Nicholas, J.
Polyphenoloxidase from apple, partial purification and some properties
Phytochemistry
28
2903-2907
1989
Malus sp.
-
Kelley, S.K.; Coyne, V.E.; Sledjeski, D.D.; Fuqua, W.C.; Weiner, R.M.
Identification of a tyrosinase from periphytic marine bacterium
FEMS Microbiol. Lett.
67
275-280
1990
uncultured marine bacterium, uncultured marine bacterium 2.40
-
Birse, C.E.; Clutterbuck, A.J.
N-acetyl-6-hydroxytryptophan oxidase, a developmentally controlled phenol oxidase from Aspergillus nidulans
J. Gen. Microbiol.
136
1725-1730
1990
Aspergillus nidulans
Terao, M.; Tabe, L.; Garattini, E.; Sartori, D.; Studer, M.; Mintz, B.
Isolation and characterization of variant cDNAs encoding mouse tyrosinase
Biochem. Biophys. Res. Commun.
159
848-853
1989
Mus musculus
Yurkow, E.J.; Laskin, J.D.
Purification of tyrosinase to homogeneity based on its resistance to sodium dodecyl sulfate-proteinase K digestion
Arch. Biochem. Biophys.
275
122-129
1989
Mus musculus
Hara, T.; Tsukamoto, T.; Watanabe, K.; Yamasaki, N.; Funatsu, M.
Properties of cuticular phenoloxidase from pupae of the housefly, Musca domestica L.
Agric. Biol. Chem.
55
13-17
1991
Musca domestica
-
Vulfson, E.N.; Ahmed, G.; Gill, I.; Kozlov, I.A.; Goodenough, P.W.; Law, B.A.
Alterations to the catalytic properties of polyphenoloxidase in detergentless microemulsions and ternary water-organic solvent mixtures
Biotechnol. Lett.
13
91-96
1991
Mushroom
-
Harris, E.B.; Sanchez, R.M.; Job, C.K.; Prabhakaran, K.; Hastings, R.C.
Isolation and characterization of an environmental acid-fast organism producing diphenoloxidase activity in vivo
FEMS Microbiol. Lett.
70
95-100
1990
Mycobacterium avium-intracellulare
-
Tanabe, N.; Sagawa, I.; Ohtsubo, K.i.; Iijima, Y.; Yanagi, S.O.
Comparison of phenoloxidase activities during the cultivation of several basidomycetes
Agric. Biol. Chem.
53
3061-3063
1989
Phanerodontia chrysosporium, Trametes versicolor, Lentinula edodes, Pleurotus ostreatus, Tremella fuciformis
-
Moore, N.L.; Mariam, D.H.; Williams, A.L.; Dashek, W.V.
Substrate specificity, de novo synthesis and partial purification of polyphenol oxidase derived from the wood-decay fungus, Coriolus versicolor
J. Ind. Microbiol.
4
349-364
1989
Trametes versicolor
-
Oda, Y.; Kato, H.; Isoda, Y.; Takahashi, N.; Yamamoto, T.; Takada, Y.; Kudo, S.
Purification and properties of phenoloxidase from spinach leaves
Agric. Biol. Chem.
53
2053-2061
1989
Spinacia oleracea
-
Kupper, U.; Niedermann, D.M.; Travaglini, G.; Lerch, K.
Isolation and characterization of the tyrosinase gene from Neurospora crassa
J. Biol. Chem.
264
17250-17258
1989
Neurospora crassa
Saul, S.J.; Sugumaran, M.
Characterization of a new enzyme system that desaturates the side chain of N-acetyldopamine
FEBS Lett.
251
69-73
1989
Sarcophaga bullata
Sderhll, I.; Sderhll, K.
Purification of prophenol oxidase from Daucus carota cell cultures
Phytochemistry
28
1805-1808
1989
Daucus carota
-
Bru, R.; Sanchez-Ferrer, A.; Garcia-Carmona, F.
Characteristics of tyrosinase in AOT-isooctane reverse micelles
Biotechnol. Bioeng.
34
304-308
1989
Mushroom
Sanchez-Ferrer, A.; Villalba, J.; Garcia-Carmona, F.
Triton X-114 as a tool for purifying spinach polyphenol oxidase
Phytochemistry
28
1321-1325
1989
Spinacia oleracea
-
Hara, T.; Tsukamoto, T.; Maruta, K.; Funatsu, M.
Purification and kinetic properties of phenoloxidase from pupae of the housefly
Agric. Biol. Chem.
53
1387-1393
1989
Musca domestica
-
Datta, T.K.; Basu, P.S.; Datta, P.K.; Banerjee, A.
Purification of a unique glycoprotein that enhances phenol oxidase activity in scorpion (Heterometrus bengalensis) haemolymph
Biochem. J.
260
525-529
1989
Deccanometrus bengalensis
Jimenez, M.; Maloy, W.L.; Hearing, V.J.
Specific identification of an authentic clone for mammalian tyrosinase
J. Biol. Chem.
264
3397-3403
1989
Mus musculus
Okamoto, A.; Imagawa, H.; Arai, Y.; Ozawa, T.
Partial purification and some properties of polyphenoloxidases from sago palm
Agric. Biol. Chem.
52
2215-2222
1988
Metroxylon sagu
-
Takeuchi, S.; Yamamoto, H.; Takeuchi, T.
Expression of tyrosinase gene in amelanotic mutant mice
Biochem. Biophys. Res. Commun.
155
470-475
1988
Mus musculus
Sanchez-Ferrer, A.; Bru, R.; Garcia-Carmona, F.
Kinetic properties of polyphenoloxidase in organic solvents. A study in Brij 96-cyclohexane reverse micelles
FEBS Lett.
233
363-366
1988
Vitis vinifera
-
Sanchez-Ferrer, A.; Bru, R.; Cabanes, J.; Garcia-Carmona, F.
Characterization of catecholase and cresolase activities of monastrell grape polyphenol oxidase
Phytochemistry
27
319-321
1988
Vitis vinifera
-
Hearing, V.J.
Mammalian monophenol monooxygenase (tyrosinase): purification, properties, and reactions catalyzed
Methods Enzymol.
142
154-165
1987
Mammalia, Mus musculus
Lerch, K.
Monophenol monooxygenase from Neurospora crassa
Methods Enzymol.
142
165-169
1987
Neurospora crassa
Flurkey, W.H.
Polyphenoloxidase in higher plants. Immunological detection and analysis of in vitro translation products
Plant Physiol.
81
614-618
1986
Vicia faba, Glycine max, Lactuca sativa, Solanum lycopersicum, Nicotiana tabacum, Phaseolus lunatus, Vigna radiata, Pisum sativum, Spinacia oleracea
Rouet-Mayer, M.A.; Philippon, J.
Inhibition of catechol oxidases from apples by sodium chloride
Phytochemistry
25
2717-2719
1986
Malus sp.
-
Wittenberg, C.; Triplett, E.L.
A detergent-activated tyrosinase from Xenopus laevis. I. Purification and partial characterization
J. Biol. Chem.
260
12535-12541
1985
Xenopus laevis
Bernan, V.; Filpula, D.; Herber, W.; Bibb, M.; Katz, E.
The nucleotide sequence of the tyrosinase gene from Streptomyces antibioticus and characterization of the gene product
Gene
37
101-110
1985
Streptomyces antibioticus
Wissemann, K.W.; Montgomery, M.W.
Purification of d'anjou pear (Pyrus communis L.) polyphenol oxidase
Plant Physiol.
78
256-262
1985
Pyrus communis
Wittenberg, C.; Triplett, E.L.
A detergent-activated tyrosinase from Xenopus laevis. II. Detergent activation and binding
J. Biol. Chem.
260
12542-12546
1985
Streptomyces antibioticus, Xenopus laevis
Sderhll, K.; Carlberg, I.; Eriksson, T.
Isolation and partial purification of prophenoloxidase from Daucus carota L. cell cultures
Plant Physiol.
78
730-733
1985
Daucus carota, Xanthisma gracile, Nicotiana tabacum
Kahn, V.; Andrawis, A.
Inhibition of mushroom tyrosinase by tropolone
Phytochemistry
24
905-908
1985
Mushroom
-
Yoshimoto, T.; Yamamoto, K.; Tsuru, D.
Extracellular tyrosinase from Streptomyces sp. KY-453: purification and some enzymatic properties
J. Biochem.
97
1747-1754
1985
Streptomyces sp.
Smith, D.M.; Montgomery, M.W.
Improved methods for the extraction of polyphenol oxidase from d'anjou pears
Phytochemistry
24
901-904
1985
Pyrus communis
-
Anosike, E.O.; Ayaebene, A.O.
Properties of polyphenol oxidase from tubers of the yam Dioscora bulbifera
Phytochemistry
21
1889-1893
1982
Dioscorea bulbifera
-
Anosike, E.O.; Ayaebene, A.O.
Purification and some properties of polyphenol oxidase from the yam tubers, Dioscorea bulbifera
Phytochemistry
20
2625-2628
1981
Dioscorea bulbifera
-
Ohkura, T.; Yamashita, K.; Mishima, Y.; Kobata, A.
Purification of hamster melanoma tyrosinases and structural studies of their asparagine-linked sugar chains
Arch. Biochem. Biophys.
235
63-77
1984
Mesocricetus auratus
Wichers, H.J.; Peetsma, G.J.; Malingre, T.M.; Huizing, H.J.
Purification and properties of a phenol oxidase derived from suspension cultures of Mucuna pruriens
Planta
162
334-341
1984
Mucuna pruriens
Woolery, G.L.; Powers, L.; Winkler, M.; Solomon, E.I.; Lerch, K.; Spiro, T.G.
Extended X-ray absorption fine structure study of the coupled binuclear copper active site of tyrosinase from Neurospora crassa
Biochim. Biophys. Acta
788
155-161
1984
Neurospora crassa
Yamamoto, H.; Brumbaugh, J.A.
Purification and isoelectric heterogeneity of chicken tyrosinase
Biochim. Biophys. Acta
800
282-290
1984
Gallus gallus
Hsu, A.F.; Kalan, E.B.; Bills, D.D.
Partial purification and characterization of the soluble polyphenol oxidases from suspension cultures of Papaver somniferum
Plant Sci. Lett.
34
315-322
1984
Papaver somniferum
-
Manjon, A.; Ferragut, J.A.; Garcia-Borron, J.C.; Iborra, J.L.
Conformational studies of soluble and immobilized frog epidermis tyrosinase by fluorescence
Appl. Biochem. Biotechnol.
9
173-185
1984
Rana esculenta ridibunda
Tremolieres, M.; Bieth, J.G.
Isolation and characterization of the polyphenoloxidase from senescent leaves of black poplar
Phytochemistry
23
501-505
1984
Populus nigra
-
Interesse, F.S.; Ruggiero, P.; D'Avella, G.; Lamparelli, F.
Characterization of wheat o-diphenolase isoenzyme
Phytochemistry
22
1885-1889
1983
Triticum aestivum
-
Goodenough, P.W.; Kessell, S.; Lea, A.G.H.; Loeffler, T.
Mono- and diphenolase activity from fruit of Malus pumila
Phytochemistry
22
359-363
1983
Malus sp.
-
Ikediobi, C.O.; Obasuyi, H.N.
Purification and some properties of o-diphenolase from white yam tubers
Phytochemistry
21
2815-2820
1982
Dioscorea cayenensis subsp. rotundata
-
Vijayan, E.; Husain, I.; Ramaiah, A.; Madan, N.C.
Purification of human skin tyrosinase and its protein inhibitor: properties of the enzyme and the mechanism of inhibition by protein
Arch. Biochem. Biophys.
217
738-747
1982
Homo sapiens
Lerch, K.; Longoni, C.; Jordi, E.
Primary structure of tyrosinase from Neurospora crassa. I. Purification and amino acid sequence of the cyanogen bromide fragments
J. Biol. Chem.
257
6408-6413
1982
Neurospora crassa
Lerch, K.
Primary structure of tyrosinase from Neurospora crassa. II. Complete amino acid sequence and chemical structure of a tripeptide containing an unusual thioether
J. Biol. Chem.
257
6414-6419
1982
Neurospora crassa
Crameri, R.; Ettlinger, L.; H. tter, R.; Lerch, K.; Suter, M.A.; Vetterli, J.A.
Secretion of tyrosinase in Streptomyces glaucescens
J. Gen. Microbiol.
128
371-379
1982
Streptomyces glaucescens
Sharma, R.C.; Ali, R.
Hydrodynamic properties of mushroom tyrosinase
Phytochemistry
20
399-401
1981
Mushroom
-
Yonekura, M.; Shimoda, T.; Funatsu, M.
Reinvestigation of purification of phenoloxidase from larvae of housefly
Agric. Biol. Chem.
45
101-104
1981
Musca domestica
-
Sharma, R.C.; Ali, R.
Isolation and characterization of catechol oxidase from Solanum melongena
Phytochemistry
19
1597-1600
1980
Solanum melongena
-
Himmelwright, R.S.; Eickman, N.C.; LuBien, C.D.; Lerch, K.; Solomon, E.I.
Chemical and spectroscopic studies of the binuclear copper active site of Neurospora tyrosinase: comparison to hemocyanins
J. Am. Chem. Soc.
102
7339-7344
1980
Neurospora crassa
-
Kahn, V.; Pomerantz, S.H.
Monophenolase activity of avocado polyphenol oxidase
Phytochemistry
19
379-385
1980
Persea americana
-
Wissemann, K.W.; Lee, C.Y.
Purification of grape polyphenoloxidase with hydrophobic chromatography
J. Chromatogr.
192
232-235
1980
Vitis vinifera
-
Yamaura, I.; Yonekura, M.; Katsura, Y.; Ishiguro, M.; Funatsu, M.
Purification and some physico-chemical properties of phenoloxidase from the larvae of housefly
Agric. Biol. Chem.
44
55-59
1980
Musca domestica
-
Menon, I.A.; Haberman, H.F.
Activation of tyrosinase in microsomes and melanosomes from B16 and Harding-Passey melanomas
Arch. Biochem. Biophys.
137
231-242
1970
Mus musculus
Yamamoto, H.; Takeuchi, S.; Kudo, T.; Makino, K.; Nakata, A.; Shinoda, T.; Takeuchi, T.
Cloning and sequencing of mouse tyrosinase cDNA
Jpn. J. Genet.
62
271-274
1987
Mus musculus
-
Chaplin, M.F.
Preparation and properties of an o-diphenol:O2 oxidoreductase from cocoa husk
Phytochemistry
17
1897-1899
1978
Theobroma cacao
-
Signoret, A.; Crouzet, J.
Activites polyphenoloxydasique et peroxydasique du fruit de la tomate (Lycopersicum esculentum) purification et quelques proprietes
Agric. Biol. Chem.
42
1871-1877
1978
Solanum lycopersicum
-
Nishioka, K.
Particulate tyrosinase of human malignant melanoma. Solubilization, purification following trypsin treatment, and characterization
Eur. J. Biochem.
85
137-146
1978
Homo sapiens
Hearing, V.J.; Ekel, T.M.; Montague, P.M.; Hearing, E.D.; Nicholson, J.M.
Mammalian tyrosinase: isolation by a simple new procedure and characterization of its steric requirements for cofactor activity
Arch. Biochem. Biophys.
185
407-418
1978
Mus musculus
Ben-Shalom, N.; Kahn, V.; Harel, E.; Mayer, A.M.
Catechol oxidase from green olives: properties and partial purification
Phytochemistry
16
1153-1158
1977
Olea europaea
-
Rih, M.; Sundman, V.
Characterization of lignosulfonate-induced phenol oxidase a in the atypical white-rot fungus Polyporus dichrous
Arch. Microbiol.
105
73-76
1975
Vitreoporus dichrous
-
Padron, M.P.; Lozano, J.A.; Gonzales, A.G.
Properties of o-diphenol:O2 oxidoreductase from Musa cavendishii
Phytochemistry
14
1959-1963
1975
Musa cavendishii
-
Pau, R.N.; Eagles, P.A.M.
The isolation of an o-diphenal oxidase from third-instar larvae of the blowfly Calliphora erythrocephala
Biochem. J.
149
707-712
1975
Calliphora vicina
Mikkelsen, R.B.; Triplett, E.L.
Tyrosinases in Rana pipiens. Purification and physical properties
J. Biol. Chem.
250
638-643
1975
Lithobates pipiens
Pomerantz, S.H.; Murthy, V.V.
Purification and properties of tyrosinases from Vibrio tyrosinaticus
Arch. Biochem. Biophys.
160
73-82
1974
Vibrio tyrosinaticus
Madhosingh, C.; Sundberg, L.
Purification and properties of tyrosinase inhibitor from mushroom
FEBS Lett.
49
156-158
1974
Agaricus hortensis
Coggon, P.; Moss, G.A.; Sanderson, G.W.
Tea catechol oxidase: isolation, purification and kinetic characterization
Phytochemistry
12
1947-1955
1973
Camellia sinensis
-
Stelzig, D.A.; Akhtar, S.; Ribeiro, S.
Catechol oxidase of red delicious apple peel
Phytochemistry
11
535-539
1972
Malus sp.
-
Pomerantz, S.H.; Li, J.P.C.
Tyrosinases (hamster melanoma)
Methods Enzymol.
17A
620-626
1970
Mesocricetus auratus
-
Horowitz, N.H.; Fling, M.; Horn, G.
Tyrosinase (Neurospora crassa)
Methods Enzymol.
17A
615-620
1970
Neurospora crassa
-
Nelson, R.M.; Mason, H.S.
Tyrosinase (mushroom)
Methods Enzymol.
17A
626-632
1970
Agaricus bisporus
-
Vanneste, W.H.; Zuberb hler, A.
Copper-containing oxygenases
Mol. Mech. Oxygen Activ. (Hayaishi, O., ed.) Academic Press, New York
New York
371-404
1974
Agaricus bisporus, Mammalia, Mushroom
-
Kwon, B.S.; Walkulchik, M.; Haq, A.K.; Halaban, R.; Kestler, D.
Sequence analysis of mouse tyrosinase cDNA and the effect of melanotropin on its gene expression
Biochem. Biophys. Res. Commun.
153
1301-1309
1988
Mus musculus
Muller, G.; Ruppert, S.; Schmid, E.; Schutz, G.
Functional analysis of alternatively spliced tyrosinase gene transcripts
EMBO J.
7
2723-2730
1988
Mus musculus
Fuller, B.B.; Lundsford, J.B.; Iman, D.S.
alpha-Melanocyte-stimulating hormone regulation of tyrosinase in Cloudman S-91 mouse melanoma cell cultures
J. Biol. Chem.
262
4024-4033
1987
Mus musculus
Flurkey, W.H.
In vitro biosynthesis of Vicia faba polyphenoloxidase
Plant Physiol.
79
564-567
1985
Vicia faba
Vaughn, K.C.; Duke, S.O.
Tentoxin-induced loss of plastidic polyphenol oxidase
Physiol. Plant.
53
421-428
1981
Vigna radiata
-
King, R.S.; Flurkey, W.H.
Effects of limited proteolysis on broad bean polyphenoloxidase
J. Sci. Food Agric.
41
231-240
1987
Vicia faba
-
Kwon, B.S.; Haq, A.K.; Pomerantz, S.H.; Halaban, R.
Isolation and sequence of a cDNA clone for human tyrosinase that maps at the mouse c-albino locus [published erratum appears in Proc Natl Acad Sci U S A 1988 Sep;85(17):6352]
Proc. Natl. Acad. Sci. USA
84
7473-7477
1987
Homo sapiens
Strothkamp, K.; Jolly, R.; Mason, H.S.
Quaternary structure of mushroom tyrosinase
Biochem. Biophys. Res. Commun.
70
519-524
1976
Agaricus bisporus
McIntyre, R.J.; Vaughan, P.F.T.
Kinetic studies on the hydroxylation of p-coumaric acid to caffeic acid by spinach-beet phenolase
Biochem. J.
149
447-461
1975
Beta vulgaris
Jimenez-Cervantes, C.; Garcia-Borron, J.C.; Valverde, P.; Solano, F.; Lozano, J.A.
Tyrosinase isoenzymes in mammalian melanocytes. 1. Biochemical characterization of two melanosomal tyrosinases from B16 mouse melanoma
Eur. J. Biochem.
217
549-556
1993
Mus musculus
Naish-Byfield, S.; Cooksey, C.J.; Riley, P.A.
Oxidation of monohydric phenol substrates by tyrosinase: effect of dithiothreitol on kinetics
Biochem. J.
304
155-162
1994
Agaricus bisporus
-
Jimenez-Cervantes, C.; Garcia-Borron, J.C.; Lozano, J.A.; Solano, F.
Effect of detergents and endogenous lipids on the activity and properties of tyrosinase and its related proteins
Biochim. Biophys. Acta
1243
421-430
1995
Mus musculus
Kanda, K.; Sato, T.; Ishii, S.; Enei, H.; Ejiri, S.
Purification and properties of tyrosinase isozymes from the gill of Lentinus edodes fruiting body
Biosci. Biotechnol. Biochem.
60
1273-1278
1996
Lentinula edodes
April, C.S.; Franz, T.; Kidson, S.H.
The cloning and characterization of chick tyrosinase from a novel embryonic cDNA library
Exp. Cell Res.
224
372-378
1996
Gallus gallus
Espin, J.C.; Trujano, M.F.; Tudela, J.; Garcia-Canovas, F.
Monophenolase Activity of Polyphenol Oxidase from Haas Avocado
J. Agric. Food Chem.
45
1091-1096
1997
Persea americana
Pialis, P.; Saville, B.A.
Production of L-DOPA from tyrosinase immobilized on nylon 6,6: enzyme stability and scaleup
Enzyme Microb. Technol.
22
261-268
1998
Mushroom
-
Hata, S.; Azumi, K.; Yokosawa, H.
Ascidian phenoloxidase: its release from hemocytes, isolation, characterization and physiological roles
Comp. Biochem. Physiol. B
119
769-776
1998
Halocynthia roretzi
Kong, K.H.; Lee, J.L.; Park, H.J.; Cho, S.H.
Purification and characterization of the tyrosinase isozymes of pine needles
Biochem. Mol. Biol. Int.
45
717-724
1998
Pinus densiflora
Rescigno, A.; Sanjust, E.; Soddu, G.; Rinaldi, A.C.; Sollai, F.; Curreli, N.; Rinaldi, A.
Effect of 3-hydroxyanthranilic acid on mushroom tyrosinase activity
Biochim. Biophys. Acta
1384
268-276
1998
Agaricus bisporus
Espin, J.C.; Jolivet, S.; Wichers, H.J.
Kinetic Study of the Oxidation of g-L-Glutaminyl-4-hydroxybenzene Catalyzed by Mushroom (Agaricus bisporus) Tyrosinase
J. Agric. Food Chem.
47
3495-3502
1999
Agaricus bisporus
Chevalier, T.; de Rigal, D.; Mbeguie-A-Mbeguie, D.; Gauillard, F.; Richard.Forget, F.; Fils-Lycaon, B.R.
Molecular cloning and characterization of apricot fruit polyphenol oxidase
Plant Physiol.
119
1261-1269
1999
Prunus armeniaca
Kong, K.H.; Park, S.Y.; Hong, M.P.; Cho, S.H.
Expression and characterization of human tyrosinase from a bacterial expression system
Comp. Biochem. Physiol. B
125
563-569
2000
Homo sapiens
Espin, J.C.; Varon, R.; Fenoll, L.G.; Gilabert, M.A.; Garcia-Ruiz, P.A.; Tudela, J.; Garcia-Canovas, F.
Kinetic characterization of the substrate specificity and mechanism of mushroom tyrosinase
Eur. J. Biochem.
267
1270-1279
2000
Agaricus bisporus
Sugumaran, M.; Nellaiappan, K.; Valivittan, K.
A new mechanism for the control of phenoloxidase activity: inhibition and complex formation with quinone isomerase
Arch. Biochem. Biophys.
379
252-260
2000
Manduca sexta, Sarcophaga bullata
Ito, M.; Oda, K.
An organic solvent resistant tyrosinase from Streptomyces sp. REN-21: purification and characterization
Biosci. Biotechnol. Biochem.
64
261-267
2000
Streptomyces sp., Mushroom
Perez-Gilabert, M.; Garcia Carmona, F.
Characterization of catecholase and cresolase activities of eggplant polyphenol oxidase
J. Agric. Food Chem.
48
695-700
2000
Solanum melongena
Kong, K.H.; Hong, M.P.; Choi, S.S.; Kim, Y.T.; Cho, S.H.
Purification and characterization of a highly stable tyrosinase from Thermomicrobium roseum
Biotechnol. Appl. Biochem.
31
113-118
2000
Thermomicrobium roseum
-
Branza-Nichita, N.; Negroiu, G.; Petrescu, A.J.; Garman, E.F.; Platt, F.M.; Wormald, M.R.; Dwek, R.A.; Petrescu, S.M.
Mutations at critical N-glycosylation sites reduce tyrosinase activity by altering folding and quality control
J. Biol. Chem.
275
8169-8175
2000
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Chazarra, S.; Garcia-Cormona, F.; Cabanes, J.
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Homo sapiens (P14679), Homo sapiens
Malkin, B.D.; Thickman, K.R.; Markworth, C.J.; Wilcox, D.E.
Kull, F.J.: Inhibition of potato polyphenol oxidase by anions and activity in various carboxylate buffers (pH4.8) at constant ionic strength
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Emerita emeritus
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Adachi, K.; Hirata, T.; Nishioka, T.; Sakaguchi, M.
Hemocyte components in crustaceans convert hemocyanin into a phenoloxidase-like enzyme
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Penaeus japonicus
Naraoka, T.; Uchisawa, H.; Mori, H.; Matsue, H.; Chiba, S.; Kimura, A.
Purification, characterization and molecular cloning of tyrosinase from the cephalopod mollusk,Illex argentinus
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Illex argentinus (Q76DT9), Illex argentinus (Q76DU0), Illex argentinus
Halaouli, S.; Asther, M.; Kruus, K.; Guo, L.; Hamdi, M.; Sigoillot, J.C.; Lomascolo, A.
Characterization of a new tyrosinase from Pycnoporus species with high potential for food technological applications
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Trametes cinnabarina, Trametes sanguinea
Liu, N.; Zhang, T.; Wang, Y.J.; Huang, Y.P.; Ou, J.H.; Shen, P.
A heat inducible tyrosinase with distinct properties from Bacillus thuringiensis
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Bacillus thuringiensis
Kohashi, P.Y.; Kumagai, T.; Matoba, Y.; Yamamoto, A.; Maruyama, M.; Sugiyama, M.
An efficient method for the overexpression and purification of active tyrosinase from Streptomyces castaneoglobisporus
Protein Expr. Purif.
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Streptomyces castaneoglobisporus, Streptomyces castaneoglobisporus HUT6202
Ha, S.K.; Koketsu, M.; Lee, K.; Choi, S.Y.; Park, J.H.; Ishihara, H.; Kim, S.Y.
Inhibition of tyrosinase activity by N,N-unsubstituted selenourea derivatives
Biol. Pharm. Bull.
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Agaricus bisporus
Okombi, S.; Rival, D.; Bonnet, S.; Mariotte, A.M.; Perrier, E.; Boumendjel, A.
Analogues of N-hydroxycinnamoylphenalkylamides as inhibitors of human melanocyte-tyrosinase
Bioorg. Med. Chem. Lett.
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Homo sapiens
Cho, S.J.; Roh, J.S.; Sun, W.S.; Kim, S.H.; Park, K.D.
N-Benzylbenzamides: A new class of potent tyrosinase inhibitors
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Agaricus bisporus
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Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future
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Granata, A.; Monzani, E.; Bubacco, L.; Casella, L.
Mechanistic insight into the activity of tyrosinase from variable-temperature studies in an aqueous/organic solvent
Chemistry
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Streptomyces antibioticus
Selinheimo, E.; Saloheimo, M.; Ahola2, E.; Westerholm-Parvinen, A.; Kalkkinen, N.; Buchert, J.; Kruus, K.
Production and characterization of a secreted, C-terminally processed tyrosinase from the filamentous fungus Trichoderma reesei
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Trichoderma reesei
Xue, C.B.; Luo, W.C.; Chen, Q.X.; Wang, Q.; Ke, L.N.
Enzymatic properties of phenoloxidase from Pieris rapae (Lepidoptera) larvae
Insect Sci.
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Pieris rapae
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Orenes-Pinero, E.; Garcia-Carmona, F.; Sanchez-Ferrer, A.
A kinetic study of p-cresol oxidation by quince fruit polyphenol oxidase
J. Agric. Food Chem.
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Cydonia oblonga
Spagna, G.; Barbagallo, R.N.; Chisari, M.; Branca, F.
Characterization of a tomato polyphenol oxidase and its role in browning and lycopene content
J. Agric. Food Chem.
53
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Solanum lycopersicum
Gandia-Herrero, F.; Nez-Atieanzar, M.J.; Cabanes, J.; Garcia-Carmona, F.; Escribano, J.
Differential activation of a latent polyphenol oxidase mediated by sodium dodecyl sulfate
J. Agric. Food Chem.
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Beta vulgaris
Gandia-Herrero, F.; Escribano, J.; Garcia-Carmona, F.
Characterization of the activity of tyrosinase on betaxanthins derived from (R)-amino acids
J. Agric. Food Chem.
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Agaricus bisporus
Olianas, A.; Sanjust, E.; Pellegrini, M.; Rescigno, A.
Tyrosinase activity and hemocyanin in the hemolymph of the slipper lobster Scyllarides latus
J. Comp. Physiol. B
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Scyllarides latus
Guelcin, I.; Kuefrevioglu, O.I.; Oktay, M.
Purification and characterization of polyphenol oxidase from nettle (Urtica dioica L.) and inhibitory effects of some chemicals on enzyme activity
J. Enzyme Inhib. Med. Chem.
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Urtica dioica
Benjakul, S.; Visessanguan, W.; Tanaka, M.
Properties of phenoloxidase isolated from the cephalothorax of kuruma prawn (Penaeus japonicus).
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Penaeus japonicus
Okombi, S.; Rival, D.; Bonnet,S.; Mariotte,A.M.; Perrier,E.; Boumendjel, A.
Discovery of benzylidenebenzofuran-3(2H)-one (aurones) as inhibitors of tyrosinase derived from human melanocytes
J. Med. Chem.
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Homo sapiens
Garcia-Molina, F.; Penalver, M.J.; Fenoll, L.G.; Rodriguez-Lopez, J.N.; Varon, R.; Gracia-Canovas, F.; Tudela, J.
Kinetic study of monophenol and o-diphenol binding to oxytyrosinase
J. Mol. Catal. B
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Nat. Prod. Res.
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Agaricus bisporus
Aclecio Melo, G.; Massao Shimizu, M.; Mazzafera, P.
Polyphenoloxidase activity in coffee leaves and its role in resistance against the coffee leaf miner and coffee leaf rust
Phytochemistry
67
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Coffea arabica, Coffea guarini, Coffea kapakata, Coffea liberica var. dewevrei, Coffea stenophylla
Wuyts, N.; De Waele, D.; Swennen, R.
Extraction and partial characterization of polyphenol oxidase from banana (Musa acuminata Grande naine) roots
Plant Physiol. Biochem.
44
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Musa acuminata
Saboury, A.A.; Alijanianzadeh, M.; Mansoori-Torshizi, H.
The role of alkyl chain length in the inhibitory effect n-alkyl xanthates on mushroom tyrosinase activities
Acta Biochim. Pol.
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Agaricus bisporus
Saiedian, S.; Keyhani, E.; Keyhani, J.
Polyphenol oxidase activity in dormant saffron (Crocus sativus L.) corm
Acta Physiol. Plant.
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Crocus sativus
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Bu, J.; Ma, P.C.; Chen, Z.Q.; Zhou, W.Q.; Fu, Y.J.; Li, L.J.; Li, C.R.
Inhibition of MITF and tyrosinase by paeonol-stimulated JNK/SAPK to reduction of phosphorylated CREB
Am. J. Chin. Med.
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Mus musculus
Tembe, S.; Kubal, B.S.; Karve, M.; DSouza, S.F.
Glutaraldehyde activated eggshell membrane for immobilization of tyrosinase from Amorphophallus companulatus: application in construction of electrochemical biosensor for dopamine
Anal. Chim. Acta
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Amorphophallus paeoniifolius var. campanulatus
Sutay Kocabas, D.; Bakir, U.; Phillips, S.E.; McPherson, M.J.; Ogel, Z.B.
Purification, characterization, and identification of a novel bifunctional catalase-phenol oxidase from Scytalidium thermophilum
Appl. Microbiol. Biotechnol.
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Mycothermus thermophilus
Bubacco, L.; Spinazze, R.; della Longa, S.; Benfatto, M.
X-ray absorption analysis of the active site of Streptomyces antibioticus tyrosinase upon binding of transition state analogue inhibitors
Arch. Biochem. Biophys.
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Streptomyces antibioticus
Campello, S.; Beltramini, M.; Giordano, G.; Di Muro, P.; Marino, S.M.; Bubacco, L.
Role of the tertiary structure in the diphenol oxidase activity of Octopus vulgaris hemocyanin
Arch. Biochem. Biophys.
471
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Octopus vulgaris
Xiao, L.; Matsubayashi, K.; Miwa, N.
Inhibitory effect of the water-soluble polymer-wrapped derivative of fullerene on UVA-induced melanogenesis via downregulation of tyrosinase expression in human melanocytes and skin tissues
Arch. Dermatol. Res.
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Homo sapiens
Munoz-Munoz, J.L.; Garcia-Molina, F.; Garcia-Ruiz, P.A.; Molina-Alarcon, M.; Tudela, J.; Garcia-Canovas, F.; Rodriguez-Lopez, J.N.
Phenolic substrates and suicide inactivation of tyrosinase: kinetics and mechanism
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Agaricus bisporus
Liu, S.H.; Pan, I.H.; Chu, I.M.
Inhibitory effect of p-hydroxybenzyl alcohol on tyrosinase activity and melanogenesis
Biol. Pharm. Bull.
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Agaricus bisporus, Mus musculus
Miyazawa, M.; Tamura, N.
Inhibitory compound of tyrosinase activity from the sprout of Polygonum hydropiper L. (Benitade)
Biol. Pharm. Bull.
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Agaricus bisporus
Hyun, S.K.; Lee, W.H.; Jeong, d.a..M.; Kim, Y.; Choi, J.S.
Inhibitory effects of kurarinol, kuraridinol, and trifolirhizin from Sophora flavescens on tyrosinase and melanin synthesis
Biol. Pharm. Bull.
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Agaricus bisporus
Tsuchiya, T.; Yamada, K.; Minoura, K.; Miyamoto, K.; Usami, Y.; Kobayashi, T.; Hamada-Sato, N.; Imada, C.; Tsujibo, H.
Purification and determination of the chemical structure of the tyrosinase inhibitor produced by Trichoderma viride strain H1-7 from a marine environment
Biol. Pharm. Bull.
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2008
Agaricus bisporus
Karioti, A.; Protopappa, A.; Megoulas, N.; Skaltsa, H.
Identification of tyrosinase inhibitors from Marrubium velutinum and Marrubium cylleneum
Bioorg. Med. Chem.
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Agaricus bisporus
Liu, J.; Yi, W.; Wan, Y.; Ma, L.; Song, H.
1-(1-Arylethylidene)thiosemicarbazide derivatives: a new class of tyrosinase inhibitors
Bioorg. Med. Chem.
16
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2008
Agaricus bisporus
Criton, M.; Le Mellay-Hamon, V.
Analogues of N-hydroxy-N-phenylthiourea and N-hydroxy-N-phenylurea as inhibitors of tyrosinase and melanin formation
Bioorg. Med. Chem. Lett.
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Agaricus bisporus
Oozeki, H.; Tajima, R.; Nihei, K.I.
Molecular design of potent tyrosinase inhibitors having the bibenzyl skeleton
Bioorg. Med. Chem. Lett.
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2008
Agaricus bisporus
Kawamura-Konishi, Y.; Tsuji, M.; Hatana, S.; Asanuma, M.; Kakuta, D.; Kawano, T.; Mukouyama, E.B.; Goto, H.; Suzuki, H.
Purification, characterization, and molecular cloning of tyrosinase from Pholiota nameko
Biosci. Biotechnol. Biochem.
71
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Pholiota nameko (A7BHQ9), Pholiota nameko
Morimura, K.; Yamazaki, C.; Hattori, Y.; Makabe, H.; Kamo, T.; Hirota, M.
A tyrosinase inhibitor, Daedalin A, from mycelial culture of Daedalea dickinsii
Biosci. Biotechnol. Biochem.
71
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2007
Agaricus bisporus
Munoz-Munoz, J.L.; Garcia-Molina, F.; Varon, R.; Rodriguez-Lopez, J.N.; Garcia-Canovas, F.; Tudela, J.
Kinetic characterization of the oxidation of esculetin by polyphenol oxidase and peroxidase
Biosci. Biotechnol. Biochem.
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Agaricus bisporus
Yang, Z.; Yue, Y.J.; Xing, M.
Tyrosinase activity in ionic liquids
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Agaricus bisporus
Nesterov, A.; Zhao, J.; Minter, D.; Hertel, C.; Ma, W.; Abeysinghe, P.; Hong, M.; Jia, Q.
1-(2,4-dihydroxyphenyl)-3-(2,4-dimethoxy-3-methylphenyl)propane, a novel tyrosinase inhibitor with strong depigmenting effects
Chem. Pharm. Bull.
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Agaricus bisporus, Mus musculus
Kennedy, L.J.; Selvi, P.K.; Padmanabhan, A.; Hema, K.N.; Sekaran, G.
Immobilization of polyphenol oxidase onto mesoporous activated carbons --isotherm and kinetic studies
Chemosphere
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Solanum tuberosum
Hristova, R.; Dolashki, A.; Voelter, W.; Stevanovic, S.; Dolashka-Angelova, P.
o-Diphenol oxidase activity of molluscan hemocyanins
Comp. Biochem. Physiol. B
149
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Helix vulgaris, Rapana venosa
McMahon, A.M.; Doyle, E.M.; Brooks, S.; OConnor, K.E.
Biochemical characterization of the coexisting tyrosinase and laccase in the soil bacterium Pseudomonas putida F6
Enzyme Microb. Technol.
40
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Pseudomonas putida, Pseudomonas putida F6
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Dogan, S.; Salman, U.
Partial characterization of lettuce (Lactuca sativa L.) polyphenol oxidase
Eur. Food Res. Technol.
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Lactuca sativa
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Liu, J.; Cao, R.; Yi, W.; Ma, C.; Wan, Y.; Zhou, B.; Ma, L.; Song, H.
A class of potent tyrosinase inhibitors: Alkylidenethiosemicarbazide compounds
Eur. J. Med. Chem.
44
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Agaricus bisporus
Nillius, D.; Jaenicke, E.; Decker, H.
Switch between tyrosinase and catecholoxidase activity of scorpion hemocyanin by allosteric effectors
FEBS Lett.
582
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Pandinus imperator
Gawlik-Dziki, U.; Szymanowska, U.; Baraniak, B.
Characterization of polyphenol oxidase from broccoli (Brassica oleracea var. botrytis italica) florets
Food Chem.
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2007
Brassica oleracea
Ayaz, F.A.; Demir, O.; Torun, H.; Kolcuoglu, Y.; Colak, A.
Characterization of polyphenoloxidase (PPO) and total phenolic contents in medlar (Mespilus germanica L.) fruit during ripening and over ripening
Food Chem.
106
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2007
Mespilus germanica
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Gawlik-Dziki, U.; Zlotek, U.; Swieca, M.
Characterization of polyphenol oxidase from butter lettuce (Lactuca sativa var. capitata L.)
Food Chem.
107
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Lactuca sativa
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Kumar, V.B.; Mohan, T.C.; Murugan, K.
Purification and kinetic characterization of polyphenol oxidase from Barbados cherry (Malpighia glabra L.)
Food Chem.
110
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2008
Malpighia glabra
Otavio de Faria, R.; Moure, V.R.; Balmant, W.; Lopes de Almeida Amazonas, M.A.; Krieger, N.; Mitchell, D.A.
The tyrosinase produced by Lentinula boryana (Berk. & Mont.) Pegler suffers substrate inhibition by L-DOPA
Food Technol. Biotechnol.
45
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2007
Lentinula boryana
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Gouzi, H.; Benmansour, A.
Partial purification and characterization of polyphenol oxidase extracted from Agaricus bisporus (J.E.Lange) Imbach
Int. J. Chem. React. Eng.
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2007
Agaricus bisporus
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Cabanes, J.; Escribano, J.; Gandia-Herrero, F.; Garcia-Carmona, F.; Jimenez-Atienzar, M.
Partial purification of latent polyphenol oxidase from peach (Prunus persica L. Cv. Catherina). Molecular properties and kinetic characterization of soluble and membrane-bound forms
J. Agric. Food Chem.
55
10446-10451
2007
Prunus persica
Saeidian, S.; Keyhani, E.; Keyhani, J.
Effect of ionic detergents, nonionic detergents, and chaotropic agents on polyphenol oxidase activity from dormant saffron (Crocus sativus L.) corms
J. Agric. Food Chem.
55
3713-3719
2007
Crocus sativus
Segovia-Bravo, K.A.; Jaren-Galan, M.; Garcia-Garcia, P.; Garrido-Fernandez, A.
Characterization of polyphenol oxidase from the Manzanilla cultivar (Olea europaea pomiformis) and prevention of browning reactions in bruised olive fruits
J. Agric. Food Chem.
55
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2007
Olea europaea
Liu, L.; Cao, S.; Xie, B.; Sun, Z.; Li, X.; Miao, W.
Characterization of polyphenol oxidase from litchi pericarp using (-)-epicatechin as substrate
J. Agric. Food Chem.
55
7140-7143
2007
Litchi chinensis
Prieto, H.; Utz, D.; Castro, A.; Aguirre, C.; Gonzalez-Agueero, M.; Valdes, H.; Cifuentes, N.; Defilippi, B.G.; Zamora, P.; Zuniga, G.; Campos-Vargas, R.
Browning in Annona cherimola fruit: role of polyphenol oxidase and characterization of a coding sequence of the enzyme
J. Agric. Food Chem.
55
9208-9218
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Annona cherimola
Schmitz, G.E.; Sullivan, M.L.; Hatfield, R.D.
Three polyphenol oxidases from red clover (Trifolium pratense) differ in enzymatic activities and activation properties
J. Agric. Food Chem.
56
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2008
Trifolium pratense (Q84YH9), Trifolium pratense (Q84YI0), Trifolium pratense (Q84YI1)
Winters, A.L.; Minchin, F.R.; Michaelson-Yeates, T.P.; Lee, M.R.; Morris, P.
Latent and active polyphenol oxidase (PPO) in red clover (Trifolium pratense) and use of a low PPO mutant to study the role of PPO in proteolysis reduction
J. Agric. Food Chem.
56
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2008
Trifolium pratense
Flurkey, A.; Cooksey, J.; Reddy, A.; Spoonmore, K.; Rescigno, A.; Inlow, J.; Flurkey, W.H.
Enzyme, protein, carbohydrate, and phenolic contaminants in commercial tyrosinase preparations: potential problems affecting tyrosinase activity and inhibition studies
J. Agric. Food Chem.
56
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2008
Agaricus bisporus (O42713), Agaricus bisporus
Masuda, T.; Odaka, Y.; Ogawa, N.; Nakamoto, K.; Kuninaga, H.
Identification of geranic acid, a tyrosinase inhibitor in lemongrass (Cymbopogon citratus)
J. Agric. Food Chem.
56
597-601
2008
Agaricus bisporus
Marles, M.A.; Vandenberg, A.; Bett, K.E.
Polyphenol Oxidase Activity and Differential Accumulation of Polyphenolics in Seed Coats of Pinto Bean (Phaseolus vulgaris L.) Characterize Postharvest Color Changes
J. Agric. Food Chem.
56
7049-7056
2008
Phaseolus vulgaris
Han, H.Y.; Lee, J.R.; Xu, W.A.; Hahn, M.J.; Yang, J.M.; Park, Y.D.
Effect of Cl- on tyrosinase: complex inhibition kinetics and biochemical implication
J. Biomol. Struct. Dyn.
25
165-171
2007
Homo sapiens
Selinheimo, E.; NiEidhin, D.; Steffensen, C.; Nielsen, J.; Lomascolo, A.; Halaouli, S.; Record, E.; OBeirne, D.; Buchert, J.; Kruus, K.
Comparison of the characteristics of fungal and plant tyrosinases
J. Biotechnol.
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Malus domestica, Trametes sanguinea, Trichoderma reesei, Agaricus bisporus (O42713), Solanum tuberosum (Q41428)
Okunji, C.; Komarnytsky, S.; Fear, G.; Poulev, A.; Ribnicky, D.M.; Awachie, P.I.; Ito, Y.; Raskin, I.
Preparative isolation and identification of tyrosinase inhibitors from the seeds of Garcinia kola by high-speed counter-current chromatography
J. Chromatogr. A
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2007
Agaricus bisporus
Chang, T.S.; Tseng, M.; Ding, H.Y.; Shou-Ku Tai, S.
Isolation and characterization of Streptomyces hiroshimensis strain TI-C3 with anti-tyrosinase activity
J. Cosmet. Sci.
59
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Agaricus bisporus
Alijanianzadeh, M.; Saboury, A.A.; Mansuri-Torshizi, H.; Haghbeen, K.; Moosavi-Movahedi, A.A.
The inhibitory effect of some new synthesized xanthates on mushroom tyrosinase activities
J. Enzyme Inhib. Med. Chem.
22
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2007
Agaricus bisporus
Garcia Molina, F.; Munoz, J.L.; Varon, R.; Rodriguez Lopez, J.N.; Garcia Canovas, F.; Tudela, J.
Effect of tetrahydropteridines on the monophenolase and diphenolase activities of tyrosinase
J. Enzyme Inhib. Med. Chem.
22
383-394
2007
Agaricus bisporus
Lu, Y.H.; Lin-Tao, Y.H.; Wang, Z.T.; Wei, D.Z.; Xiang, H.B.
Mechanism and inhibitory effect of galangin and its flavonoid mixture from Alpinia officinarum on mushroom tyrosinase and B16 murine melanoma cells
J. Enzyme Inhib. Med. Chem.
22
433-438
2007
Agaricus bisporus
Zhang, C.; Lu, Y.; Tao, L.; Tao, X.; Su, X.; Wei, D.
Tyrosinase inhibitory effects and inhibition mechanisms of nobiletin and hesperidin from citrus peel crude extracts
J. Enzyme Inhib. Med. Chem.
22
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2007
Agaricus bisporus
Shiino, M.; Watanabe, Y.; Umezawa, K.
pH-dependent inhibition of mushroom tyrosinase by N-substituted N-nitrosohydroxylamines
J. Enzyme Inhib. Med. Chem.
23
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Agaricus bisporus
Guan, S.; Su, W.; Wang, N.; Li, P.; Wang, Y.
Effects of radix polygoni multiflori components on tyrosinase activity and melanogenesis
J. Enzyme Inhib. Med. Chem.
23
252-255
2008
Agaricus bisporus, Mus musculus
Sakiroglu, H.; Oztuerk, A.E.; Pepe, A.E.; Erat, M.
Some kinetic properties of polyphenol oxidase obtained from dill (Anethum graveolens)
J. Enzyme Inhib. Med. Chem.
23
380-385
2008
Anethum graveolens
Ryu, Y.B.; Ha, T.J.; Curtis-Long, M.J.; Ryu, H.W.; Gal, S.W.; Park, K.H.
Inhibitory effects on mushroom tyrosinase by flavones from the stem barks of Morus lhou (S.) Koidz
J. Enzyme Inhib. Med. Chem.
23
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2008
Agaricus bisporus
Momtaz, S.; Mapunya, B.M.; Houghton, P.J.; Edgerly, C.; Hussein, A.; Naidoo, S.; Lall, N.
Tyrosinase inhibition by extracts and constituents of Sideroxylon inerme L. stem bark, used in South Africa for skin lightening
J. Ethnopharmacol.
119
507-512
2008
Agaricus bisporus
Chao, A.
Preparation of porous chitosan/GPTMS hybrid membrane and its application in affinity sorption for tyrosinase purification with Agaricus bisporus
J. Membr. Sci.
311
306-318
2008
Agaricus bisporus
-
Orenes-Pinero, E.; Garcia-Carmona, F.; Sanchez-Ferrer, A.
Kinetic characterization of diphenolase activity from Streptomyces antibioticus tyrosinase in the presence and absence of cyclodextrins
J. Mol. Catal. B
47
143-148
2007
Streptomyces antibioticus
-
Takara, K.; Iwasaki, H.; Ujihara, K.; Wada, K.
Human tyrosinase inhibitor in rum distillate wastewater
J. Oleo Sci.
57
191-196
2008
Homo sapiens
Kim, D.S.; Lee, S.; Lee, H.K.; Park, S.H.; Ryoo, I.J.; Yoo, I.D.; Kwon, S.B.; Baek, K.J.; Na, J.I.; Park, K.C.
The hypopigmentary action of KI-063 (a new tyrosinase inhibitor) combined with terrein
J. Pharm. Pharmacol.
60
343-348
2008
Agaricus bisporus, Mus musculus
Zheng, Z.P.; Cheng, K.W.; To, J.T.; Li, H.; Wang, M.
Isolation of tyrosinase inhibitors from Artocarpus heterophyllus and use of its extract as antibrowning agent
Mol. Nutr. Food Res.
52
1530-1538
2008
Agaricus bisporus
Gao, H.; Nishida, J.; Saito, S.; Kawabata, J.
Inhibitory effects of 5,6,7-trihydroxyflavones on tyrosinase
Molecules
12
86-97
2007
Agaricus bisporus
Chien, C.C.; Tsai, M.L.; Chen, C.C.; Chang, S.J.; Tseng, C.H.
Effects on tyrosinase activity by the extracts of Ganoderma lucidum and related mushrooms
Mycopathologia
166
117-120
2008
Agaricus bisporus
Setty, S.R.; Tenza, D.; Sviderskaya, E.V.; Bennett, D.C.; Raposo, G.; Marks, M.S.
Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes
Nature
454
1142-1146
2008
Mus musculus
Thangasamy, T.; Sittadjody, S.; Lanza-Jacoby, S.; Wachsberger, P.R.; Limesand, K.H.; Burd, R.
Quercetin selectively inhibits bioreduction and enhances apoptosis in melanoma cells that overexpress tyrosinase
Nutr. Cancer
59
258-268
2007
Agaricus bisporus
Abdel-Halim, O.B.; Marzouk, A.M.; Mothana, R.; Awadh, N.
A new tyrosinase inhibitor from Crinum yemense as potential treatment for hyperpigmentation
Pharmazie
63
405-407
2008
Agaricus bisporus
Brack, A.; Hellmann, N.; Decker, H.
Kinetic properties of hexameric tyrosinase from the crustacean Palinurus elephas
Photochem. Photobiol.
84
692-699
2008
Palinurus elephas
Veljovic-Jovanovic, S.; Kukavica, B.; Navari-Izzo, F.
Characterization of polyphenol oxidase changes induced by desiccation of Ramonda serbica leaves
Physiol. Plant.
132
407-416
2008
Ramonda serbica
Lin, Y.P.; Hsu, F.L.; Chen, C.S.; Chern, J.W.; Lee, M.H.
Constituents from the Formosan apple reduce tyrosinase activity in human epidermal melanocytes
Phytochemistry
68
1189-1199
2007
Agaricus bisporus, Homo sapiens
Ryu, Y.B.; Westwood, I.M.; Kang, N.S.; Kim, H.Y.; Kim, J.H.; Moon, Y.H.; Park, K.H.
Kurarinol, tyrosinase inhibitor isolated from the root of Sophora flavescens
Phytomedicine
15
612-618
2008
Agaricus bisporus
Ullah, F.; Hussain, H.; Hussain, J.; Bukhari, I.A.; Khan, M.T.; Choudhary, M.I.; Gilani, A.H.; Ahmad, V.U.
Tyrosinase inhibitory pentacyclic triterpenes and analgesic and spasmolytic activities of methanol extracts of Rhododendron collettianum
Phytother. Res.
21
1076-1081
2007
Agaricus bisporus
Parvez, S.; Kang, M.; Chung, H.S.; Bae, H.
Naturally occurring tyrosinase inhibitors: mechanism and applications in skin health, cosmetics and agriculture industries
Phytother. Res.
21
805-816
2007
Agaricus bisporus, Beta vulgaris, Neurospora crassa, Streptomyces glaucescens
Leu, Y.L.; Hwang, T.L.; Hu, J.W.; Fang, J.Y.
Anthraquinones from Polygonum cuspidatum as tyrosinase inhibitors for dermal use
Phytother. Res.
22
552-556
2008
Agaricus bisporus
Guan, S.; Su, W.; Wang, N.; Li, P.; Wang, Y.
A potent tyrosinase activator from Radix Polygoni multiflori and its melanogenesis stimulatory effect in B16 melanoma cells
Phytother. Res.
22
660-663
2008
Agaricus bisporus, Mus musculus
Schweikardt, T.; Olivares, C.; Solano, F.; Jaenicke, E.; Garcia-Borron, J.C.; Decker, H.
A three-dimensional model of mammalian tyrosinase active site accounting for loss of function mutations
Pigment Cell Res.
20
394-401
2007
Mus musculus (P11344), Mus musculus
Magid, A.A.; Voutquenne-Nazabadioko, L.; Bontemps, G.; Litaudon, M.; Lavaud, C.
Tyrosinase inhibitors and sesquiterpene diglycosides from Guioa villosa
Planta Med.
74
55-60
2008
Agaricus bisporus
Westerholm-Parvinen, A.; Selinheimo, E.; Boer, H.; Kalkkinen, N.; Mattinen, M.; Saloheimo, M.
Expression of the Trichoderma reesei tyrosinase 2 in Pichia pastoris: isotopic labeling and physicochemical characterization
Protein Expr. Purif.
55
147-158
2007
Trichoderma reesei (A0ZXZ4), Trichoderma reesei
Olcer, H.; Kocacaliskan, I.
Excess boron reduces polyphenol oxidase activities in embryo and endosperm of maize seed during germination
Z. Naturforsch. C
62
111-115
2007
Zea mays
Sutay Kocabas, D.; Pearson, A.R.; Phillips, S.E.; Bakir, U.; Ogel, Z.B.; McPherson, M.J.; Trinh, C.H.
Crystallization and preliminary X-ray analysis of a bifunctional catalase-phenol oxidase from Scytalidium thermophilum
Acta Crystallogr. Sect. F
65
486-488
2009
Mycothermus thermophilus
Chen, C.Q.; Li, Z.C.; Pan, Z.Z.; Zhu, Y.J.; Yan, R.R.; Wang, Q.; Yan, J.H.; Chen, Q.X.
Inactivation kinetics of polyphenol oxidase from pupae of blowfly (Sarcophaga bullata) in the dimethyl sulfoxide solution
Appl. Biochem. Biotechnol.
160
2166-2174
2009
Sarcophaga bullata
Wan, X.; Chai, B.; Liao, Y.; Su, Y.; Ye, T.; Shen, P.; Chen, X.
Molecular and biochemical characterization of a distinct tyrosinase involved in melanin production from Aeromonas media
Appl. Microbiol. Biotechnol.
82
261-269
2009
Aeromonas media (B2Z3P7), Aeromonas media, Aeromonas media WS (B2Z3P7)
Jirawattanapong, W.; Saifah, E.; Patarapanich, C.
Synthesis of glabridin derivatives as tyrosinase inhibitors
Arch. Pharm. Res.
32
647-654
2009
Agaricus bisporus
Munoz-Munoz, J.L.; Garcia-Molina, F.; Garcia-Ruiz, P.A.; Varon, R.; Tudela, J.; Garcia-Canovas, F.; Rodriguez-Lopez, J.N.
Stereospecific inactivation of tyrosinase by L- and D-ascorbic acid
Biochim. Biophys. Acta
1794
244-253
2009
Agaricus bisporus
Le Mellay-Hamon, V.; Criton, M.
Phenylethylamide and phenylmethylamide derivatives as new tyrosinase inhibitors
Biol. Pharm. Bull.
32
301-303
2009
Agaricus bisporus
Yi, W.; Cao, R.; Wen, H.; Yan, Q.; Zhou, B.; Wan, Y.; Ma, L.; Song, H.
Synthesis and biological evaluation of helicid analogues as mushroom tyrosinase inhibitors
Bioorg. Med. Chem. Lett.
18
6490-6493
2008
Agaricus bisporus
Kang, S.S.; Kim, H.J.; Jin, C.; Lee, Y.S.
Synthesis of tyrosinase inhibitory (4-oxo-4H-pyran-2-yl)acrylic acid ester derivatives
Bioorg. Med. Chem. Lett.
19
188-191
2009
Agaricus bisporus
Yamazaki, Y.; Kawano, Y.; Yamanaka, A.; Maruyama, S.
N-[(dihydroxyphenyl)acyl]serotonins as potent inhibitors of tyrosinase from mouse and human melanoma cells
Bioorg. Med. Chem. Lett.
19
4178-4182
2009
Homo sapiens, Mus musculus
Yi, W.; Cao, R.; Wen, H.; Yan, Q.; Zhou, B.; Ma, L.; Song, H.
Discovery of 4-functionalized phenyl-O-beta-D-glycosides as a new class of mushroom tyrosinase inhibitors
Bioorg. Med. Chem. Lett.
19
6157-6160
2009
Agaricus bisporus
Baek, Y.S.; Ryu, Y.B.; Curtis-Long, M.J.; Ha, T.J.; Rengasamy, R.; Yang, M.S.; Park, K.H.
Tyrosinase inhibitory effects of 1,3-diphenylpropanes from Broussonetia kazinoki
Bioorg. Med. Chem.
17
35-41
2009
Agaricus bisporus
Ng, L.T.; Ko, H.H.; Lu, T.M.
Potential antioxidants and tyrosinase inhibitors from synthetic polyphenolic deoxybenzoins
Bioorg. Med. Chem.
17
4360-4366
2009
Agaricus bisporus
Chiku, K.; Dohi, H.; Saito, A.; Ebise, H.; Kouzai, Y.; Shinoyama, H.; Nishida, Y.; Ando, A.
Enzymatic synthesis of 4-hydroxyphenyl beta-D-oligoxylosides and their notable tyrosinase inhibitory activity
Biosci. Biotechnol. Biochem.
73
1123-1128
2009
Agaricus bisporus
Yi, W.; Cao, R.H.; Chen, Z.Y.; Yu, L.; Ma, L.; Song, H.C.
Design, synthesis and biological evaluation of hydroxy- or methoxy-substituted phenylmethylenethiosemicarbazones as tyrosinase inhibitors
Chem. Pharm. Bull.
57
1273-1277
2009
Agaricus bisporus
Fan, T.; Zhang, Y.; Yang, L.; Yang, X.; Jiang, G.; Yu, M.; Cong, R.
Identification and characterization of a hemocyanin-derived phenoloxidase from the crab Charybdis japonica
Comp. Biochem. Physiol. B
152
144-149
2009
Charybdis japonica
Zanna, P.T.; Maida, I.; Arciuli, M.; Jimenez-Cervantes, C.; Garcia-Borron, J.C.; Cicero, R.; Guida, G.
Molecular cloning and biochemical characterization of the skin tyrosinase from Rana esculenta L.
Comp. Biochem. Physiol. B
152
234-242
2009
Pelophylax lessonae
Thomas-Guyon, H.; Gagnaire, B.; Bado-Nilles, A.; Bouilly, K.; Lapegue, S.; Renault, T.
Detection of phenoloxidase activity in early stages of the Pacific oyster Crassostrea gigas (Thunberg)
Dev. Comp. Immunol.
33
653-659
2009
Crassostrea gigas
Selinheimo, E.; Gasparetti, C.; Mattinen, M.; Steffensen, C.; Buchert, J.; Kruus, K.
Comparison of substrate specificity of tyrosinases from Trichoderma reesei and Agaricus bisporus
Enzyme Microb. Technol.
44
1-10
2009
Agaricus bisporus, Trichoderma reesei
-
Lee, K.H.; Ab Aziz, F.H.; Syahida, A.; Abas, F.; Shaari, K.; Israf, D.A.; Lajis, N.H.
Synthesis and biological evaluation of curcumin-like diarylpentanoid analogues for anti-inflammatory, antioxidant and anti-tyrosinase activities
Eur. J. Med. Chem.
44
3195-3200
2009
Agaricus bisporus
Perry, M.J.; Mendes, E.; Simplicio, A.L.; Coelho, A.; Soares, R.V.; Iley, J.; Moreira, R.; Francisco, A.P.
Dopamine- and tyramine-based derivatives of triazenes: activation by tyrosinase and implications for prodrug design
Eur. J. Med. Chem.
44
3228-3234
2009
Agaricus bisporus
Yan, Q.; Cao, R.; Yi, W.; Chen, Z.; Wen, H.; Ma, L.; Song, H.
Inhibitory effects of 5-benzylidene barbiturate derivatives on mushroom tyrosinase and their antibacterial activities
Eur. J. Med. Chem.
44
4235-4243
2009
Agaricus bisporus
Nikodinovic-Runic, J.; Martin, L.B.; Babu, R.; Blau, W.; OConnor, K.E.
Characterization of melanin-overproducing transposon mutants of Pseudomonas putida F6
FEMS Microbiol. Lett.
298
174-183
2009
Pseudomonas putida
Gao, Z.; Han, X.; Xiao, X.
Purification and characterisation of polyphenol oxidase from red Swiss chard (Beta vulgaris subspecies cicla) leaves
Food Chem.
117
342-348
2009
Beta vulgaris
-
Yi, W.; Wu, X.; Cao, R.; Song, H.; Ma, L.
Biological evaluations of novel vitamin C esters as mushroom tyrosinase inhibitors and antioxidants
Food Chem.
117
381-386
2009
Agaricus bisporus
Tsao, I.Y.; Lin, U.S.; Christensen, B.M.; Chen, C.C.
Armigeres subalbatus prophenoloxidase III: Cloning, characterization and potential role in morphogenesis
Insect Biochem. Mol. Biol.
39
96-104
2009
Armigeres subalbatus (Q6RX65), Armigeres subalbatus
Munoz-Munoz, J.L.; Garcia-Molina, F.; Garcia-Molina, M.; Tudela, J.; Garcia-Canovas, F.; Rodriguez-Lopez, J.N.
Ellagic acid: characterization as substrate of polyphenol oxidase
IUBMB Life
61
171-177
2009
Agaricus bisporus
Garcia-Carreno, F.L.; Cota, K.; Navarrete Del Toro, M.A.
Phenoloxidase activity of hemocyanin in whiteleg shrimp Penaeus vannamei: conversion, characterization of catalytic properties, and role in postmortem melanosis
J. Agric. Food Chem.
56
6454-6459
2008
Penaeus vannamei
Jeong, S.H.; Ryu, Y.B.; Curtis-Long, M.J.; Ryu, H.W.; Baek, Y.S.; Kang, J.E.; Lee, W.S.; Park, K.H.
Tyrosinase inhibitory polyphenols from roots of Morus lhou
J. Agric. Food Chem.
57
1195-1203
2009
Agaricus bisporus
Liu, W.; Liu, J.; Xie, M.; Liu, C.; Liu, W.; Wan, J.
Characterization and high-pressure microfluidization-induced activation of polyphenoloxidase from Chinese pear (Pyrus pyrifolia Nakai)
J. Agric. Food Chem.
57
5376-5380
2009
Pyrus pyrifolia
Van Ranst, G.; Fievez, V.; Vandewalle, M.; De Riek, J.; Van Bockstaele, E.
In vitro study of red clover polyphenol oxidase activity, activation, and effect on measured lipase activity and lipolysis
J. Agric. Food Chem.
57
6611-6617
2009
Trifolium pratense
Bandyopadhyay, P.; Jha, S.; Imran Ali, S.K.
Picolyl alkyl amines as novel tyrosinase inhibitors: Influence of hydrophobicity and substitution
J. Agric. Food Chem.
57
9780-9786
2009
Agaricus bisporus
Gou, L.; Lu, Z.R.; Park, D.; Sang, H.; Shi, L.; Seong, J.; Bhak, J.; Park, Y.; Ren, Z.; Zou, F.
The effect of histidine residue modification on tyrosinase activity and conformation: Inhibition kinetics and computational prediction
J. Biomol. Struct. Dyn.
26
395-401
2008
Agaricus bisporus
Xue, C.B.; Luo, W.C.; Ding, Q.; Liu, S.Z.; Gao, X.X.
Quantitative structure-activity relationship studies of mushroom tyrosinase inhibitors
J. Comput. Aided Mol. Des.
22
299-309
2008
Agaricus bisporus
Zhuang, J.X.; Li, W.G.; Qiu, L.; Zhong, X.; Zhou, J.J.; Chen, Q.X.
Inhibitory effects of Cefazolin and Cefodizime on the activity of mushroom tyrosinase
J. Enzyme Inhib. Med. Chem.
24
251-256
2009
Agaricus bisporus
Dedeoglu, N.; Guler, O.O.
Differential in vitro inhibition of polyphenoloxidase from a wild edible mushroom Lactarius salmonicolor
J. Enzyme Inhib. Med. Chem.
24
464-470
2009
Lactarius salmonicolor
Abu Ubeid, A.; Zhao, L.; Wang, Y.; Hantash, B.M.
Short-sequence oligopeptides with inhibitory activity against mushroom and human tyrosinase
J. Invest. Dermatol.
129
2242-2249
2009
Agaricus bisporus, Homo sapiens
Shuster, V.; Fishman, A.
Isolation, cloning and characterization of a tyrosinase with improved activity in organic solvents from Bacillus megaterium
J. Mol. Microbiol. Biotechnol.
17
188-200
2009
Priestia megaterium
Wu, B.; Chen, J.; Qu, H.; Cheng, Y.
Complex sesquiterpenoids with tyrosinase inhibitory activity from the leaves of Chloranthus tianmushanensis
J. Nat. Prod.
71
877-880
2008
Agaricus bisporus
Antonella Fai, A.F.; Corda, M.; Era, B.; Fadda, M.; Matos, M.; Quezada, E.; Santana, L.; Picciau, C.; Podda, G.; Delogu, G.
Tyrosinase inhibitor activity of coumarin-resveratrol hybrids
Molecules
14
2514-2520
2009
Agaricus bisporus
Nithitanakool, S.; Pithayanukul, P.; Bavovada, R.; Saparpakorn, P.
Molecular docking studies and anti-tyrosinase activity of Thai mango seed kernel extract
Molecules
14
257-265
2009
Agaricus bisporus
Cai, G.; Bae, Y.; Zhang, Y.; He, Y.; Jiang, M.; He, L.
Expression and characterization of two tyrosinases from the trematode Schistosoma japonicum
Parasitol. Res.
104
601-609
2009
Schistosoma japonicum (Q5DB10), Schistosoma japonicum (Q5DHS0), Schistosoma japonicum
Parveen, I.; Winters, A.; Threadgill, M.D.; Hauck, B.; Morris, P.
Extraction, structural characterisation and evaluation of hydroxycinnamate esters of orchard grass (Dactylis glomerata) as substrates for polyphenol oxidase
Phytochemistry
69
2799-2806
2008
Dactylis glomerata
Olivares, C.; Solano, F.
New insights into the active site structure and catalytic mechanism of tyrosinase and its related proteins
Pigment Cell Melanoma Res.
22
750-760
2009
Gallus gallus, Homo sapiens, Mus musculus, Streptomyces castaneoglobisporus
Nugroho, A.; Choi, J.K.; Park, J.H.; Lee, K.T.; Cha, B.C.; Park, H.J.
Two new flavonol glycosides from Lamium amplexicaule L. and their in vitro free radical scavenging and tyrosinase inhibitory activities
Planta Med.
75
364-366
2009
Agaricus bisporus
Sendovski, M.; Kanteev, M.; Shuster Ben-Yosef, V.; Adir, N.; Fishman, A.
Crystallization and preliminary X-ray crystallographic analysis of a bacterial tyrosinase from Bacillus megaterium
Acta Crystallogr. Sect. F
66
1101-1103
2010
Priestia megaterium
Ismaya, W.T.; Rozeboom, H.J.; Schurink, M.; Boeriu, C.G.; Wichers, H.; Dijkstra, B.W.
Crystallization and preliminary X-ray crystallographic analysis of tyrosinase from the mushroom Agaricus bisporus
Acta Crystallogr. Sect. F
67
575-578
2011
Agaricus bisporus (O42713), Agaricus bisporus
Holzapfel, C.; Shahrokh, P.; Kafkewitz, D.
Polyphenol oxidase activity in the roots of seedlings of Bromus (Poaceae) and other grass genera
Am. J. Bot.
97
1195-1199
2010
Bromus erectus, Bromus inermis, Bromus tectorum, Bromus carinatus, Bromus fasciculatus, Bromus hordeaceus, Bromus japonicus, Bromus kalmii, Bromus madritensis, Bromus diandrus var. rigidus
Guo, Y.J.; Pan, Z.Z.; Chen, C.Q.; Hu, Y.H.; Liu, F.J.; Shi, Y.; Yan, J.H.; Chen, Q.X.
Inhibitory effects of fatty acids on the activity of mushroom tyrosinase
Appl. Biochem. Biotechnol.
162
1564-1573
2010
Agaricus bisporus
Marino, S.M.; Fogal, S.; Bisaglia, M.; Moro, S.; Scartabelli, G.; De Gioia, L.; Spada, A.; Monzani, E.; Casella, L.; Mammi, S.; Bubacco, L.
Investigation of Streptomyces antibioticus tyrosinase reactivity toward chlorophenols
Arch. Biochem. Biophys.
505
67-74
2011
Streptomyces antibioticus
Takahashi, T.; Miyazawa, M.
Synthesis and structure-activity relationships of phenylpropanoid amides of serotonin on tyrosinase inhibition
Bioorg. Med. Chem. Lett.
21
1983-1986
2011
Agaricus bisporus
Ghani, U.; Ullah, N.
New potent inhibitors of tyrosinase: novel clues to binding of 1,3,4-thiadiazole-2(3H)-thiones, 1,3,4-oxadiazole-2(3H)-thiones, 4-amino-1,2,4-triazole-5(4H)-thiones, and substituted hydrazides to the dicopper active site
Bioorg. Med. Chem.
18
4042-4048
2010
Agaricus bisporus
Chiari, M.E.; Vera, D.M.; Palacios, S.M.; Carpinella, M.C.
Tyrosinase inhibitory activity of a 6-isoprenoid-substituted flavanone isolated from Dalea elegans
Bioorg. Med. Chem.
19
3474-3482
2011
Agaricus bisporus
Pang, Q.; Liu, X.; Zhao, B.; Jiang, Y.; Su, F.; Zhang, X.; Nie, M.; Zhang, M.; Sun, H.
Detection and characterization of phenoloxidase in the freshwater planarian Dugesia japonica
Comp. Biochem. Physiol. B
157
54-58
2010
Dugesia japonica
Shuster Ben-Yosef, V.; Sendovski, M.; Fishman, A.
Directed evolution of tyrosinase for enhanced monophenolase/diphenolase activity ratio
Enzyme Microb. Technol.
47
372-376
2010
Priestia megaterium
-
Oezel, A.; Colak, A.; Arslan, O.; Yildirim, M.
Purification and characterisation of a polyphenol oxidase from Boletus erythropus and investigation of its catalytic efficiency in selected organic solvents
Food Chem.
119
1044-1049
2010
Neoboletus erythropus
Lin, M.; Ke, L.; Han, P.; Qiu, L.; Chen, Q.; Lin, H.; Wang, Q.
Inhibitory effects of p-alkylbenzoic acids on the activity of polyphenol oxidase from potato (Solanum tuberosum)
Food Chem.
119
660-663
2010
Solanum tuberosum
Sun, Y.; He, Z.; Ma, W.; Xia, X.
Alternative splicing in the coding region of Ppo-A1 directly influences the polyphenol oxidase activity in common wheat (Triticum aestivum L.)
Funct. Integr. Genomics
11
85-93
2011
Triticum aestivum
Li, Z.C.; Chen, L.H.; Yu, X.J.; Hu, Y.H.; Song, K.K.; Zhou, X.W.; Chen, Q.X.
Inhibition kinetics of chlorobenzaldehyde thiosemicarbazones on mushroom tyrosinase
J. Agric. Food Chem.
58
12537-12540
2010
Agaricus bisporus
Marita, J.M.; Hatfield, R.D.; Brink, G.
In vitro proteolytic inhibition, polyphenol oxidase activity, and soluble o-diphenols in grasses and cereals
J. Agric. Food Chem.
58
959-966
2010
Avena sativa, Bromus inermis, Dactylis glomerata, Elymus repens, Lolium arundinaceum, Lolium sp., Poa pratensis, Secale cereale, Triticum aestivum, Phleum pratense, Festuca pratensis, Phalaris arundinacea, Festuca sp.
Xu, D.Y.; Yang, Y.; Yang, Z.
Activity and stability of cross-linked tyrosinase aggregates in aqueous and nonaqueous media
J. Biotechnol.
152
30-36
2011
Agaricus bisporus
Amin, E.; Saboury, A.; Mansuri-Torshizi, H.; Moosavi-Movahedi, A.
Potent inhibitory effects of benzyl and p-xylidine-bis dithiocarbamate sodium salts on activities of mushroom tyrosinase
J. Enzyme Inhib. Med. Chem.
25
272-281
2010
Agaricus bisporus
Zhu, Z.; Zhan, L.
Characterization of polyphenol oxidase from water caltrop (Trapa acornis Nakano) fruits
J. Food Biochem.
34
1125-1140
2010
Trapa acornis
Ni Eidhin, D.; Degn, P.; Obeirne, D.
Characterization of polyphenol oxidase from rooster potato (Solanum tuberosum cv Rooster)
J. Food Biochem.
34
13-30
2010
Solanum tuberosum
Genta, F.A.; Souza, R.S.; Garcia, E.S.; Azambuja, P.
Phenol oxidases from Rhodnius prolixus: temporal and tissue expression pattern and regulation by ecdysone
J. Insect Physiol.
56
1253-1259
2010
Rhodnius prolixus
Sendovski, M.; Kanteev, M.; Ben-Yosef, V.S.; Adir, N.; Fishman, A.
First structures of an active bacterial tyrosinase reveal copper plasticity
J. Mol. Biol.
405
227-237
2011
Priestia megaterium (B2ZB02), Priestia megaterium
Chatzistathis, T.; Therios, I.; Diamantidis, G.
Polyphenol oxidase activity of two olive (Olea europaea L.) cultivars as an early criterion of Mn toxicity
J. Sci. Food Agric.
90
676-682
2010
Olea europaea
Newman, S.M.; Tantasawat, P.; Steffens, J.C.
Tomato polyphenol oxidase B is spatially and temporally regulated during development and in response to ethylene
Molecules
16
493-517
2011
Solanum lycopersicum
Takahashi, T.; Miyazawa, M.
Tyrosinase inhibitory activities of cinnamic acid analogues
Pharmazie
65
913-918
2010
Agaricus bisporus
Shimizu, M.M.; Melo, G.A.; Brombini Dos Santos, A.; Bottcher, A.; Cesarino, I.; Araujo, P.; Magalhaes Silva Moura, J.C.; Mazzafera, P.
Enzyme characterisation, isolation and cDNA cloning of polyphenol oxidase in the hearts of palm of three commercially important species
Plant Physiol. Biochem.
49
970-977
2011
Bactris gasipaes, Euterpe oleracea (Q3YJ63), Euterpe oleracea, Euterpe edulis (Q45NF5), Euterpe edulis
Diwakar, S.K.; Mishra, S.K.
Purification and biochemical characterization of ionically unbound polyphenol oxidase from Musa paradisiaca leaf
Prep. Biochem. Biotechnol.
41
187-200
2011
Musa x paradisiaca
Goldfeder, M.; Egozy, M.; Shuster Ben-Yosef, V.; Adir, N.; Fishman, A.
Changes in tyrosinase specificity by ionic liquids and sodium dodecyl sulfate
Appl. Microbiol. Biotechnol.
97
1953-1961
2013
Priestia megaterium (B2ZB02), Priestia megaterium
Munoz-Munoz, J.L.; Berna, J.; Garcia-Molina, M.d.e.l..M.; Garcia-Molina, F.; Garcia-Ruiz, P.A.; Varon, R.; Rodriguez-Lopez, J.N.; Garcia-Canovas, F.
Hydroxylation of p-substituted phenols by tyrosinase: further insight into the mechanism of tyrosinase activity
Biochem. Biophys. Res. Commun.
424
228-233
2012
Agaricus bisporus
Connor, K.L.; Colabroy, K.L.; Gerratana, B.
A heme peroxidase with a functional role as an L-tyrosine hydroxylase in the biosynthesis of anthramycin
Biochemistry
50
8926-8936
2011
Streptomyces refuineus
Goldfeder, M.; Kanteev, M.; Adir, N.; Fishman, A.
Influencing the monophenolase/diphenolase activity ratio in tyrosinase
Biochim. Biophys. Acta
1834
629-633
2013
Priestia megaterium (B2ZB02), Priestia megaterium
Wang, Y.; Curtis-Long, M.; Lee, B.; Yuk, H.; Kim, D.; Tan, X.; Park, K.
Inhibition of tyrosinase activity by polyphenol compounds from Flemingia philippinensis roots
Bioorg. Med. Chem.
22
1115-1120
2014
Agaricus bisporus
Molloy, S.; Nikodinovic-Runic, J.; Martin, L.B.; Hartmann, H.; Solano, F.; Decker, H.; OConnor, K.E.
Engineering of a bacterial tyrosinase for improved catalytic efficiency towards D-tyrosine using random and site directed mutagenesis approaches
Biotechnol. Bioeng.
110
1849-1857
2013
Ralstonia solanacearum (Q8Y2J8), Ralstonia solanacearum
Hamann, J.N.; Tuczek, F.
New catalytic model systems of tyrosinase: fine tuning of the reactivity with pyrazole-based N-donor ligands
Chem. Commun. (Camb. )
50
2298-2300
2014
Streptomyces castaneoglobisporus
Kolcuoglu, Y.
Purification and comparative characterization of monophenolase and diphenolase activities from a wild edible mushroom (Macrolepiota gracilenta)
Process Biochem.
47
2449-2454
2012
Macrolepiota gracilenta
-
Lai, X.; Soler-Lopez, M.; Ismaya, W.; Wichers, H.; Dijkstra, B.
Crystal structure of recombinant tyrosinase-binding protein MtaL at 1.35% resolution
Acta Crystallogr. Sect. F
72
244-250
2016
Agaricus bisporus (C7FF04), Agaricus bisporus
Kampatsikas, I.; Bijelic, A.; Pretzler, M.; Rompel, A.
In crystallo activity tests with latent apple tyrosinase and two mutants reveal the importance of the mutated sites for polyphenol oxidase activity
Acta Crystallogr. Sect. F
73
491-499
2017
Malus domestica (P43309), Malus domestica
Liu, D.M.; Yang, J.L.; Ha, W.; Chen, J.; Shi, Y.P.
Kinetics and inhibition study of tyrosinase by pressure mediated microanalysis
Anal. Biochem.
525
54-59
2017
Agaricus bisporus
Hu, J.J.; Bai, X.L.; Liu, Y.M.; Liao, X.
Functionalized carbon quantum dots with dopamine for tyrosinase activity analysis
Anal. Chim. Acta
995
99-105
2017
Agaricus bisporus
Bijelic, A.; Pretzler, M.; Molitor, C.; Zekiri, F.; Rompel, A.
The structure of a plant tyrosinase from walnut leaves reveals the importance of substrate-guiding residues for enzymatic specificity
Angew. Chem. Int. Ed. Engl.
54
14677-14680
2015
Juglans regia
Agarwal, P.; Singh, J.; Singh, R.P.
Molecular cloning and characteristic features of a novel extracellular tyrosinase from Aspergillus niger PA2
Appl. Biochem. Biotechnol.
182
1-15
2017
Aspergillus niger (A0A140CTD1), Aspergillus niger, Aspergillus niger PA2 (A0A140CTD1)
Jantakee, K.; Tragoolpua, Y.
Activities of different types of Thai honey on pathogenic bacteria causing skin diseases, tyrosinase enzyme and generating free radicals
Biol. Res.
48
4-4
2015
Agaricus bisporus
Ramsden, C.A.; Riley, P.A.
Tyrosinase the four oxidation states of the active site and their relevance to enzymatic activation, oxidation and inactivation
Bioorg. Med. Chem.
22
2388-2395
2014
Agaricus bisporus
Ortiz-Ruiz, C.V.; Berna, J.; Garcia-Molina, M.d.e.l. .M.; Tudela, J.; Tomas, V.; Garcia-Canovas, F.
Identification of p-hydroxybenzyl alcohol, tyrosol, phloretin and its derivate phloridzin as tyrosinase substrates
Bioorg. Med. Chem.
23
3738-3746
2015
Agaricus bisporus
Ashraf, Z.; Rafiq, M.; Seo, S.Y.; Babar, M.M.; Zaidi, N.U.
Synthesis, kinetic mechanism and docking studies of vanillin derivatives as inhibitors of mushroom tyrosinase
Bioorg. Med. Chem.
23
5870-5880
2015
Agaricus bisporus
Garcia-Jimenez, A.; Teruel-Puche, J.A.; Berna, J.; Rodriguez-Lopez, J.N.; Tudela, J.; Garcia-Ruiz, P.A.; Garcia-Canovas, F.
Characterization of the action of tyrosinase on resorcinols
Bioorg. Med. Chem.
24
4434-4443
2016
Agaricus bisporus
Wang, R.; Chai, W.M.; Yang, Q.; Wei, M.K.; Peng, Y.
2-(4-Fluorophenyl)-quinazolin-4(3H)-one as a novel tyrosinase inhibitor Synthesis, inhibitory activity, and mechanism
Bioorg. Med. Chem.
24
4620-4625
2016
Agaricus bisporus
Channar, P.A.; Saeed, A.; Larik, F.A.; Rafiq, M.; Ashraf, Z.; Jabeen, F.; Fattah, T.A.
Synthesis, computational studies and enzyme inhibitory kinetics of substituted methyl[(2-(4-dimethylamino-benzylidene)-hydrazono)-4-oxo-thiazolidin-5-ylidene]acetates as mushroom tyrosinase inhibitors
Bioorg. Med. Chem.
25
5929-5938
2017
Agaricus bisporus
Oyama, T.; Yoshimori, A.; Takahashi, S.; Yamamoto, T.; Sato, A.; Kamiya, T.; Abe, H.; Abe, T.; Tanuma, S.I.
Structural insight into the active site of mushroom tyrosinase using phenylbenzoic acid derivatives
Bioorg. Med. Chem. Lett.
27
2868-2872
2017
Agaricus bisporus
Radhakrishnan, S.K.; Shimmon, R.G.; Conn, C.; Baker, A.T.
Inhibitory kinetics of azachalcones and their oximes on mushroom tyrosinase a facile solid-state synthesis
Chem. Biodivers.
13
531-538
2016
Agaricus bisporus
Abbas, Q.; Raza, H.; Hassan, M.; Phull, A.R.; Kim, S.J.; Seo, S.Y.
Acetazolamide inhibits the level of tyrosinase and melanin an enzyme kinetic, in vitro, in vivo, and in silico studies
Chem. Biodivers.
14
e1700117
2017
Agaricus bisporus, Danio rerio, Homo sapiens
Brasil, E.M.; Canavieira, L.M.; Cardoso, E.T.C.; Silva, E.O.; Lameira, J.; Nascimento, J.L.M.; Eifler-Lima, V.L.; Macchi, B.M.; Sriram, D.; Bernhardt, P.V.; Silva, J.R.A.; Williams, C.M.; Alves, C.N.
Inhibition of tyrosinase by 4H-chromene analogs Synthesis, kinetic studies, and computational analysis
Chem. Biol. Drug Des.
90
804-810
2017
Agaricus bisporus
Dolinska, M.B.; Wingfield, P.T.; Sergeev, Y.V.
Purification of recombinant human tyrosinase from insect larvae infected with the baculovirus vector
Curr. Protoc. Protein Sci.
89
15.1-6.15.12
2017
Homo sapiens (P14679), Homo sapiens
Zaidi, K.U.; Ali, A.S.; Ali, S.A.
Purification and characterization of melanogenic enzyme tyrosinase from button mushroom
Enzyme Res.
2014
120739
2014
Agaricus bisporus
Nokinsee, D.; Shank, L.; Lee, V.S.; Nimmanpipug, P.
Estimation of inhibitory effect against tyrosinase activity through homology modeling and molecular docking
Enzyme Res.
2015
262364
2015
Agaricus bisporus, Homo sapiens (P14679), Homo sapiens
Uemit Uenal, M.; Sener, A.
Effect of harvest year on biochemical properties of Narince grape (Vitis vinifera l. cv. Narince) polyphenol oxidase
Eur. Food Res. Technol.
238
613-619
2014
Vitis vinifera
-
Larik, F.A.; Saeed, A.; Channar, P.A.; Muqadar, U.; Abbas, Q.; Hassan, M.; Seo, S.Y.; Bolte, M.
Design, synthesis, kinetic mechanism and molecular docking studies of novel 1-pentanoyl-3-arylthioureas as inhibitors of mushroom tyrosinase and free radical scavengers
Eur. J. Med. Chem.
141
273-281
2017
Agaricus bisporus
Fronk, P.; Hartmann, H.; Bauer, M.; Solem, E.; Jaenicke, E.; Tenzer, S.; Decker, H.
Polyphenoloxidase from Riesling and Dornfelder wine grapes (Vitis vinifera) is a tyrosinase
Food Chem.
183
49-57
2015
Vitis vinifera
Sullivan, M.
Beyond brown polyphenol oxidases as enzymes of plant specialized metabolism
Front. Plant Sci.
5
1-7
2015
Antirrhinum majus (Q9FRX6), Beta vulgaris, Coreopsis grandiflora (A0A075BX21), Juglans regia, Larrea tridentata (Q6UIL3), no activity in Arabidopsis thaliana
Gou, L.; Lee, J.; Hao, H.; Park, Y.D.; Zhan, Y.; Lue, Z.R.
The effect of oxaloacetic acid on tyrosinase activity and structure Integration of inhibition kinetics with docking simulation
Int. J. Biol. Macromol.
101
59-66
2017
Agaricus bisporus
Hu, Y.H.; Chen, Q.X.; Cui, Y.; Gao, H.J.; Xu, L.; Yu, X.Y.; Wang, Y.; Yan, C.L.; Wang, Q.
4-Hydroxy cinnamic acid as mushroom preservation anti-tyrosinase activity kinetics and application
Int. J. Biol. Macromol.
86
489-495
2016
Agaricus bisporus
Cai, X.; Hong, Y.; Wang, S.; Zhao, L.; Rao, P.
Purification and enzymatic characteristics of a novel polyphenol oxidase from lotus seed (Nelumbo nucifera Gaertn.)
Int. J. Food Sci. Technol.
50
1026-1032
2015
Nelumbo nucifera (A0A1U7Z3Y9)
-
del Mar Garcia-Molina, M.; Munoz-Munoz, J.L.; Berna, J.; Garcia-Ruiz, P.A.; Rodriguez-Lopez, J.N.; Garcia-Canovas, F.
Catalysis and inactivation of tyrosinase in its action on hydroxyhydroquinone
IUBMB Life
66
122-127
2014
Agaricus bisporus
Ortiz-Ruiz, C.V.; Maria-Solano, M.A.; Garcia-Molina, M.d.e.l. .M.; Varon, R.; Tudela, J.; Tomas, V.; Garcia-Canovas, F.
Kinetic characterization of substrate-analogous inhibitors of tyrosinase
IUBMB Life
67
757-767
2015
Agaricus bisporus
Ortiz-Ruiz, C.V.; Ballesta de Los Santos, M.; Berna, J.; Fenoll, J.; Garcia-Ruiz, P.A.; Tudela, J.; Garcia-Canovas, F.
Kinetic characterization of oxyresveratrol as a tyrosinase substrate
IUBMB Life
67
828-836
2015
Agaricus bisporus
Patil, S.; Sistla, S.; Jadhav, J.
Screening of inhibitors for mushroom tyrosinase using surface plasmon resonance
J. Agric. Food Chem.
62
11594-11601
2014
Agaricus bisporus
Palma-Orozco, G.; Marrufo-Hernandez, N.A.; Sampedro, J.G.; Najera, H.
Purification and partial biochemical characterization of polyphenol oxidase from mango (Mangifera indica cv. Manila)
J. Agric. Food Chem.
62
9832-9840
2014
Mangifera indica
Asthana, S.; Zucca, P.; Vargiu, A.V.; Sanjust, E.; Ruggerone, P.; Rescigno, A.
Structure-activity relationship study of hydroxycoumarins and mushroom tyrosinase
J. Agric. Food Chem.
63
7236-7244
2015
Agaricus bisporus
Chai, W.M.; Wei, M.K.; Wang, R.; Deng, R.G.; Zou, Z.R.; Peng, Y.Y.
Avocado proanthocyanidins as a source of tyrosinase inhibitors structure characterization, inhibitory activity, and mechanism
J. Agric. Food Chem.
63
7381-7387
2015
Agaricus bisporus
Liu, X.; Jia, Y.L.; Chen, J.W.; Liang, G.; Guo, H.Y.; Hu, Y.H.; Shi, Y.; Zhou, H.T.; Chen, Q.X.
Inhibition effects of benzylideneacetone, benzylacetone, and 4-phenyl-2-butanol on the activity of mushroom tyrosinase
J. Biosci. Bioeng.
119
275-279
2015
Agaricus bisporus
Harir, M.; Bellahcene, M.; Baratto, M.C.; Pollini, S.; Rossolini, G.M.; Trabalzini, L.; Fatarella, E.; Pogni, R.
Isolation and characterization of a novel tyrosinase produced by Sahara soil actinobacteria and immobilization on nylon nanofiber membranes
J. Biotechnol.
265
54-64
2017
uncultured bacterium, Streptomyces cyaneofuscatus, Streptomyces cyaneofuscatus (A0A2H4QH72), Streptomyces cyaneofuscatus Ms1, Streptomyces cyaneofuscatus NRRL B-2570 (A0A2H4QH72)
Feng, X.; Liu, F.; Lin, C.; Lin, X.; Liu, N.; Wang, X.
Purification and characterization of polyphenol oxidase from the bud of Lonicera confusa
J. Food Biochem.
38
533-541
2014
Lonicera confusa
-
Li, R.; Li, N.; Wang, Z.; Wang, X.; Liu, W.
Characterization of polyphenol oxidase from Jipicao Yam
J. Food Biochem.
39
173-178
2015
Dioscorea polystachya
-
Batista, K.; Batista, G.; Alves, G.; Fernandes, K.
Extraction, partial purification and characterization of polyphenol oxidase from Solanum lycocarpum fruits
J. Mol. Catal. B
102
211-217
2014
Solanum lycocarpum
-
Ilesanmi, O.; Ojopagogo, Y.; Adewale, I.
Kinetic characteristics of purified tyrosinase from different species of Dioscorea (YAM) in aqueous and non-aqueous systems
J. Mol. Catal. B
108
111-117
2014
Dioscorea cayenensis subsp. rotundata, Colocasia esculenta, Dioscorea praehensilis, Dioscorea alata
-
Le Roes-Hill, M.; Palmer, Z.; Rohland, J.; Kirby, B.; Burton, S.
Partial purification and characterisation of two actinomycete tyrosinases and their application in cross-linking reactions
J. Mol. Catal. B
122
353-364
2015
Streptomyces pharetrae, Streptomyces polyantibioticus, Streptomyces polyantibioticus SPR, Streptomyces pharetrae CZA14
-
Teng, J.; Gong, Z.; Deng, Y.; Chen, L.; Li, Q.; Shao, Y.; Lin, L.; Xiao, W.
Purification, characterization and enzymatic synthesis of theaflavins of polyphenol oxidase isozymes from tea leaf (Camellia sinensis)
LWT-Food Sci. Technol.
84
263-270
2017
Camellia sinensis (C0L3S4), Camellia sinensis (Q68NI4)
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Fogal, S.; Carotti, M.; Giaretta, L.; Lanciai, F.; Nogara, L.; Bubacco, L.; Bergantino, E.
Human tyrosinase produced in insect cells a landmark for the screening of new drugs addressing its activity
Mol. Biotechnol.
57
45-57
2015
Streptomyces antibioticus (P07524), Homo sapiens (P14679), Homo sapiens
Lima, C.R.; Silva, J.R.; de Tassia Carvalho Cardoso, E.; Silva, E.O.; Lameira, J.; do Nascimento, J.L.; do Socorro Barros Brasil, D.; Alves, C.N.
Combined kinetic studies and computational analysis on kojic acid analogous as tyrosinase inhibitors
Molecules
19
9591-9605
2014
Agaricus bisporus
Goldfeder, M.; Kanteev, M.; Isaschar-Ovdat, S.; Adir, N.; Fishman, A.
Determination of tyrosinase substrate-binding modes reveals mechanistic differences between type-3 copper proteins
Nat. Commun.
5
4505
2014
Priestia megaterium
Zekiri, F.; Molitor, C.; Mauracher, S.G.; Michael, C.; Mayer, R.L.; Gerner, C.; Rompel, A.
Purification and characterization of tyrosinase from walnut leaves (Juglans regia)
Phytochemistry
101
5-15
2014
Juglans regia (C0LU17)
Bin, B.H.; Bhin, J.; Yang, S.H.; Shin, M.; Nam, Y.J.; Choi, D.H.; Shin, D.W.; Lee, A.Y.; Hwang, D.; Cho, E.G.; Lee, T.R.
Membrane-associated transporter protein (MATP) regulates melanosomal pH and influences tyrosinase activity
PLoS ONE
10
e0129273
2015
Homo sapiens
Chai, W.M.; Wang, R.; Wei, M.K.; Zou, Z.R.; Deng, R.G.; Liu, W.S.; Peng, Y.Y.
Proanthocyanidins extracted from Rhododendron pulchrum leaves as source of tyrosinase inhibitors structure, activity, and mechanism
PLoS ONE
10
e0145483
2015
Agaricus bisporus
Garcia-Jimenez, A.; Teruel-Puche, J.A.; Berna, J.; Rodriguez-Lopez, J.N.; Tudela, J.; Garcia-Canovas, F.
Action of tyrosinase on alpha and beta-arbutin A kinetic study
PLoS ONE
12
e0177330
2017
Agaricus bisporus
Ashraf, Z.; Rafiq, M.; Nadeem, H.; Hassan, M.; Afzal, S.; Waseem, M.; Afzal, K.; Latip, J.
Carvacrol derivatives as mushroom tyrosinase inhibitors; synthesis, kinetics mechanism and molecular docking studies
PLoS ONE
12
e0178069
2017
Agaricus bisporus (C7FF04)
Garcia-Jimenez, A.; Teruel-Puche, J.A.; Garcia-Ruiz, P.A.; Saura-Sanmartin, A.; Berna, J.; Garcia-Canovas, F.; Rodriguez-Lopez, J.N.
Structural and kinetic considerations on the catalysis of deoxyarbutin by tyrosinase
PLoS ONE
12
e0187845
2017
Agaricus bisporus (C7FF04)
Gomes, M.; Vieira, T.; Fundo, J.; Almeida, D.
Polyphenoloxidase activity and browning in fresh-cut Rocha pear as affected by pH, phenolic substrates, and antibrowning additives
Postharvest Biol. Technol.
91
32-38
2014
Pyrus communis subsp. caucasica (A7J0M6)
-
Ionita, E.; Gurgu, L.; Aprodu, I.; Stanciuc, N.; Dalmadi, I.; Bahrim, G.; Rapeanu, G.
Characterization, purification, and temperature/pressure stability of polyphenol oxidase extracted from plums (Prunus domestica)
Process Biochem.
56
177-185
2017
Prunus domestica
-
Singh, S.; Singh, D.; Kumar, S.
Expression and biochemical analysis of codon-optimized polyphenol oxidase from Camellia sinensis (L.) O. Kuntze in E. coli
Process Biochem.
59
180-186
2016
Camellia sinensis (C0L3S4)
-
Zheng, J.; Zhang, R.; Chen, Y.; Ye, X.; Chen, Q.; Shen, D.; Wang, Q.
Synthesis of caffeic acid ester morpholines and their activation effects on tyrosinase
Process Biochem.
62
91-98
2017
Agaricus bisporus, Homo sapiens (P14679)
-
Pretzler, M.; Bijelic, A.; Rompel, A.
Heterologous expression and characterization of functional mushroom tyrosinase (AbPPO4)
Sci. Rep.
7
1810
2017
Agaricus bisporus (C7FF05), Agaricus bisporus
Lien, C.Y.; Chen, C.Y.; Lai, S.T.; Chan, C.F.
Kinetics of mushroom tyrosinase and melanogenesis inhibition by N-acetyl-pentapeptides
ScientificWorldJournal
2014
409783
2014
Agaricus bisporus
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