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Information on EC 1.14.13.84 - 4-hydroxyacetophenone monooxygenase

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IUBMB Comments
Contains FAD. The enzyme from Pseudomonas fluorescens ACB catalyses the conversion of a wide range of acetophenone derivatives. Highest activity occurs with compounds bearing an electron-donating substituent at the para position of the aromatic ring . In the absence of substrate, the enzyme can act as an NAD(P)H oxidase (EC 1.6.3.1).
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
hapmo, 4-hydroxyacetophenone monooxygenase, arylketone monooxygenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(4-hydroxyphenyl)ethan-1-one + NADPH + H+ + O2 = 4-hydroxyphenyl acetate + NADP+ + H2O
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