Information on EC 1.14.13.174 - averantin hydroxylase

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The expected taxonomic range for this enzyme is: Aspergillus parasiticus

EC NUMBER
COMMENTARY hide
1.14.13.174
-
RECOMMENDED NAME
GeneOntology No.
averantin hydroxylase
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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(1'S)-averantin + NADPH + H+ + O2 = (1'S,5'R)-5'-hydroxyaverantin + NADP+ + H2O
show the reaction diagram
(2)
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-
-
(1'S)-averantin + NADPH + H+ + O2 = (1'S,5'S)-5'-hydroxyaverantin + NADP+ + H2O
show the reaction diagram
(1)
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-
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
(1'S,5'S)-averufin biosynthesis
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-
Aflatoxin biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
(1'S)-averantin,NADPH:O2 oxidoreductase (5'-hydroxylating)
A heme-thiolate (P-450) monooxygenase isolated from Aspergillus parasiticus. There is no reaction with (1'R)-averantin. Involved in aflatoxin biosynthesis.
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
metabolism
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(1'S)-averantin + NADPH + H+ + O2
(1'S,5'R)-5'-hydroxyaverantin + NADP+ + H2O
show the reaction diagram
(1'S)-averantin + NADPH + H+ + O2
(1'S,5'S)-5'-hydroxyaverantin + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
averantin + NADPH + H+ + O2
5'-hydroxyaverantin + NADP+ + H2O
show the reaction diagram
additional information
?
-
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(1'S)-averantin + NADPH + H+ + O2
(1'S,5'R)-5'-hydroxyaverantin + NADP+ + H2O
show the reaction diagram
(1'S)-averantin + NADPH + H+ + O2
(1'S,5'S)-5'-hydroxyaverantin + NADP+ + H2O
show the reaction diagram
-
-
-
-
?
averantin + NADPH + H+ + O2
5'-hydroxyaverantin + NADP+ + H2O
show the reaction diagram
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
56300
-
x * 56300, calculated from amino acid sequence
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE