Reference on EC 1.13.11.71 - carotenoid-9',10'-cleaving dioxygenase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Vage, D.I.; Boman, I.A.
A nonsense mutation in the beta-carotene oxygenase 2 (BCO2) gene is tightly associated with accumulation of carotenoids in adipose tissue in sheep (Ovis aries)
BMC Genet.
11
10
2010
Ovis aries (C1L3B1)
Kim, Y.; Yeom, S.; Oh, D.
Production of beta-apo-10'-carotenal from beta-carotene by human beta-carotene-9',10'-oxygenase expressed in E. coli
Biotechnol. Lett.
33
1195-1200
2011
Homo sapiens (Q9BYV7)
Amengual, J.; Lobo, G.; Golczak, M.; Li, H.; Klimova, T.; Hoppel, C.; Wyss, A.; Palczewski, K.; Von Lintig, J.
A mitochondrial enzyme degrades Carotenoids and protects against oxidative stress
FASEB J.
25
948-959
2011
Mus musculus (Q99NF1)
Kiefer, C.; Hessel, S.; Lampert, J.; Vogt, K.; Lederer, M.; Breithaupt, D.; Von Lintig, J.
Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A
J. Biol. Chem.
276
14110-14116
2001
Mus musculus (Q99NF1), Homo sapiens (Q9BYV7)
Schwartz, S.H.; Qin, X.; Loewen, M.C.
The biochemical characterization of two carotenoid cleavage enzymes from Arabidopsis indicates that a carotenoid-derived compound inhibits lateral branching
J. Biol. Chem.
279
46940-46945
2004
Arabidopsis thaliana (Q7XJM2)
Lindqvist, A.; He, Y.G.; Andersson, S.
Cell type-specific expression of beta-carotene 9',10'-monooxygenase in human tissues
J. Histochem. Cytochem.
53
1403-1412
2005
Homo sapiens (Q9BYV7)
Ledger, S.E.; Janssen, B.J.; Karunairetnam, S.; Wang, T.; Snowden, K.C.
Modified CAROTENOID CLEAVAGE DIOXYGENASE8 expression correlates with altered branching in kiwifruit (Actinidia chinensis)
New Phytol.
188
803-813
2010
Actinidia chinensis (E3T3A3)
Auldridge, M.E.; Block, A.; Vogel, J.T.; Dabney-Smith, C.; Mila, I.; Bouzayen, M.; Magallanes-Lundback, M.; DellaPenna, D.; McCarty, D.R.; Klee, H.J.
Characterization of three members of the Arabidopsis carotenoid cleavage dioxygenase family demonstrates the divergent roles of this multifunctional enzyme family
Plant J.
45
982-993
2006
Arabidopsis thaliana (Q7XJM2)
Lobo, G.P.; Isken, A.; Hoff, S.; Babino, D.; von Lintig, J.
BCDO2 acts as a carotenoid scavenger and gatekeeper for the mitochondrial apoptotic pathway
Development
139
2966-2977
2012
Danio rerio, Homo sapiens
Amengual, J.; Widjaja-Adhi, M.A.; Rodriguez-Santiago, S.; Hessel, S.; Golczak, M.; Palczewski, K.; von Lintig, J.
Two carotenoid-oxygenases contribute to mammalian pro-vitamin A metabolism
J. Biol. Chem.
288
34081-34096
2013
Mus musculus
Liu, J.; Novero, M.; Charnikhova, T.; Ferrandino, A.; Schubert, A.; Ruyter-Spira, C.; Bonfante, P.; Lovisolo, C.; Bouwmeester, H.J.; Cardinale, F.
Carotenoid cleavage dioxygenase 7 modulates plant growth, reproduction, senescence, and determinate nodulation in the model legume Lotus japonicus
J. Exp. Bot.
64
1967-1981
2013
Lotus japonicus
Amengual, J.; Gouranton, E.; van Helden, Y.G.; Hessel, S.; Ribot, J.; Kramer, E.; Kiec-Wilk, B.; Razny, U.; Lietz, G.; Wyss, A.; Dembinska-Kiec, A.; Palou, A.; Keijer, J.; Landrier, J.F.; Bonet, M.L.; von Lintig, J.
Beta-carotene reduces body adiposity of mice via BCMO1
PLoS ONE
6
e20644
2011
Mus musculus
Kim, Y.K.; Zuccaro, M.V.; Costabile, B.K.; Rodas, R.; Quadro, L.
Tissue- and sex-specific effects of beta-carotene 15,15' oxygenase (BCO1) on retinoid and lipid metabolism in adult and developing mice
Arch. Biochem. Biophys.
572
11-18
2015
Mus musculus (Q99NF1), Mus musculus C57BL/6 (Q99NF1)
Raghuvanshi, S.; Reed, V.; Blaner, W.S.; Harrison, E.H.
Cellular localization of ?-carotene 15,15 oxygenase-1 (BCO1) and beta-carotene 9,10 oxygenase-2 (BCO2) in rat liver and intestine
Arch. Biochem. Biophys.
572
19-27
2015
Rattus norvegicus (A3KN98)
Wei, T.; Jia, B.; Huang, S.; Yang, K.; Jia, C.; Mao, D.
Purification and characterization of a novel beta-carotene-9',10'-oxygenase from Saccharomyces cerevisiae ULI3
Biotechnol. Lett.
37
1993-1998
2015
Saccharomyces cerevisiae, Saccharomyces cerevisiae ULI3
Jlali, M.; Graulet, B.; Chauveau-Duriot, B.; Godet, E.; Praud, C.; Nunes, C.S.; Le Bihan-Duval, E.; Berri, C.; Duclos, M.J.
Nutrigenetics of carotenoid metabolism in the chicken a polymorphism at the beta,beta-carotene 15,15'-mono-oxygenase 1 (BCMO1) locus affects the response to dietary beta-carotene
Br. J. Nutr.
111
2079-2088
2014
Gallus gallus
Dela Sena, C.; Sun, J.; Narayanasamy, S.; Riedl, K.M.; Yuan, Y.; Curley, R.W.; Schwartz, S.J.; Harrison, E.H.
Substrate specificity of purified recombinant chicken beta-carotene 9',10'-oxygenase (BCO2)
J. Biol. Chem.
291
14609-14619
2016
Homo sapiens (B2RCV8), Gallus gallus (E1C8E0)
Guo, X.; Wu, L.; Lyu, Y.; Chowanadisai, W.; Clarke, S.L.; Lucas, E.A.; Smith, B.J.; He, H.; Wang, W.; Medeiros, D.M.; Lin, D.
Ablation of beta,beta-carotene-9,10-oxygenase 2 remodels the hypothalamic metabolome leading to metabolic disorders in mice
J. Nutr. Biochem.
46
74-82
2017
Mus musculus (Q99NF1)
Gong, X.; Marisiddaiah, R.; Zaripheh, S.; Wiener, D.; Rubin, L.P.
Mitochondrial beta-carotene 9',10' oxygenase modulates prostate cancer growth via NF-kappaB inhibition a lycopene-independent function
Mol. Cancer Res.
14
966-975
2016
Homo sapiens (Q9BYV7)
Li, B.; Vachali, P.P.; Gorusupudi, A.; Shen, Z.; Sharifzadeh, H.; Besch, B.M.; Nelson, K.; Horvath, M.M.; Frederick, J.M.; Baehr, W.; Bernstein, P.S.
Inactivity of human beta,beta-carotene-9',10'-dioxygenase (BCO2) underlies retinal accumulation of the human macular carotenoid pigment
Proc. Natl. Acad. Sci. USA
111
10173-10178
2014
Mus musculus (Q99NF1), Mus musculus, Homo sapiens (Q9BYV7), Homo sapiens, Mus musculus C57/BL6 (Q99NF1)
Meng, N.; Yan, G.L.; Zhang, D.; Li, X.Y.; Duan, C.Q.; Pan, Q.H.
Characterization of two Vitis vinifera carotenoid cleavage dioxygenases by heterologous expression in Saccharomyces cerevisiae
Mol. Biol. Rep.
46
6311-6323
2019
Vitis vinifera (U3M7F6), Vitis vinifera (U3M7R9)
Wu, L.; Guo, X.; Hartson, S.D.; Davis, M.A.; He, H.; Medeiros, D.M.; Wang, W.; Clarke, S.L.; Lucas, E.A.; Smith, B.J.; von Lintig, J.; Lin, D.
Lack of beta, beta-carotene-9',10'-oxygenase 2 leads to hepatic mitochondrial dysfunction and cellular oxidative stress in mice
Mol. Nutr. Food Res.
61
10
2017
Mus musculus (Q99NF1)
html completed
