Information on EC 1.1.4.B1 - prostamide synthase

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The enzyme appears in viruses and cellular organisms

EC NUMBER
COMMENTARY hide
1.1.4.B1
preliminary BRENDA-supplied EC number
RECOMMENDED NAME
GeneOntology No.
prostamide synthase
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SYSTEMATIC NAME
IUBMB Comments
prostamide F2alpha:oxidized thioredoxin oxidoreductase
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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
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prostaglandin ethanolamide, i.e. prostamide, F2alpha is a COX-2-catalyzed metabolite of arachidonoyl ethanolamide (anandamide) that induces pharmacological actions in ocular tissues. Prostamide/PGF synthase catalyzes the reductions of prostamide H2 to prostamide F2alpha and PGH2 to PGF2alpha, chiefly in the central nervous system