Disease on EC 1.1.1.43 - phosphogluconate 2-dehydrogenase
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Abortion, Spontaneous
[Role of disorders of pentosephosphate pathway of glucose oxidation in the pathogenesis of the arrest of fetal development in miscarriage]
Acidosis
Stimulation of rat-kidney hexose monophosphate shunt dehydrogenase activity by chronic metabolic acidosis.
Acquired Immunodeficiency Syndrome
Escherichia coli 6-phosphogluconate dehydrogenase aids in tellurite resistance by reducing the toxicant in a NADPH-dependent manner.
Acquired Immunodeficiency Syndrome
Slow-binding inhibition of 6-phosphogluconate dehydrogenase by zinc ion.
Alzheimer Disease
Crystal structure of Saccharomyces cerevisiae 6-phosphogluconate dehydrogenase Gnd1.
Alzheimer Disease
Increased cerebral glucose-6-phosphate dehydrogenase activity in Alzheimer's disease may reflect oxidative stress.
Anemia
The relationship between red cell aging and enzyme activities in experimental animals.
Anemia, Hemolytic
Congenital 6-phosphogluconate dehydrogenase (6PGD) deficiency associated with chronic hemolytic anemia in a Spanish family.
Anemia, Hemolytic
[6 cases of inherited nonspherocytic hemolytic anemia associated with a deficit of 6-phosphogluconate dehydrogenase in the erythrocytes]
Anemia, Hemolytic
[Congenital nonspherocytic hemolytic anemia with incomplete deficiency of 6-phosphogluconate dehydrogenase]
Anemia, Hemolytic, Congenital
[Hereditary hemolytic anemia associated with insufficient activity of 6-phosphogluconate dehydrogenase of erythrocytes with hemoglobinuria following administration of drugs]
Anemia, Hemolytic, Congenital Nonspherocytic
[Congenital nonspherocytic hemolytic anemia with incomplete deficiency of 6-phosphogluconate dehydrogenase]
Anemia, Iron-Deficiency
The investigation of plasma glucose-6-phosphate dehydrogenase, 6-phoshogluconate dehydrogenase, glutathione reductase in premenauposal patients with iron deficiency anemia.
Arsenic Poisoning
[Glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase activity in arsenic poisoning and in hypoxemia caused by sodium nitrite.]
Ascorbic Acid Deficiency
Phagocytosis and leukocyte enzymes in ascorbic acid deficient guinea pigs.
Avitaminosis
[Limited-time feeding ("meal-feeding") and avitaminosis A : respiratory exchange and metabolic adaptation in rats]
beta-Thalassemia
[Study of the enzymatic activities in the erythrocytes and platelets of subjects with Mediterranean anemia. V. Glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase activities of thalassemic platelets]
Breast Neoplasms
Effects of opiates and naloxone on certain enzymes of carbohydrate metabolism in human breast carcinomas.
Breast Neoplasms
Inhibiting 6-phosphogluconate dehydrogenase selectively targets breast cancer through AMPK activation.
Breast Neoplasms
Oxidative Pentose Phosphate Pathway Enzyme 6-Phosphogluconate Dehydrogenase Plays a Key Role in Breast Cancer Metabolism.
Breast Neoplasms
The effects of the administration of tamoxifen, ethynyloestradiol, and prednisolone on the activities of certain enzymes of carbohydrate metabolism in primary human breast carcinomas in vivo.
Breast Neoplasms
The value of 6-phosphogluconate dehydrogenase (6-PGDH) activity as a marker of tumour cellularity and prognostic indicator in primary breast cancer.
Carcinogenesis
6-Phosphogluconate dehydrogenase fuels multiple aspects of cancer cells: From cancer initiation to metastasis and chemoresistance.
Carcinogenesis
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Carcinoma
A randomized clinical trial to investigate the usefulness of the addition of prednisolone to tamoxifen as adjuvants to mastectomy in primary breast cancer patients with a high risk of recurrence: a preliminary report.
Carcinoma
Determination of 6-PGDH in the vaginal secretions of patients with carcinoma of the cervix. A new method of collection of vaginal secretions.
Carcinoma
Evaluation of 6-phosphogluconate dehydrogenase in carcinoma in situ of the cervix.
Carcinoma
The early diagnosis of carcinoma of the female genital tract. I. 6-phosphogluconate dehydrogenase activity and carcinoma of the female genital tract.
Carcinoma
The early diagnosis of carcinoma of the female genital tract. II. Vaginal fluid 6-phosphogluconate dehydrogenase activity as a test for carcinoma of the cervix.
Carcinoma
The effects of the administration of tamoxifen, ethynyloestradiol, and prednisolone on the activities of certain enzymes of carbohydrate metabolism in primary human breast carcinomas in vivo.
Carcinoma
USE OF 6-PHOSPHOGLUCONATE DEHYDROGENASE AS A SCREEN TEST FOR CERVICAL CARCINOMA IN NORMAL WOMEN.
Carcinoma
[Histoenzymatic studies of cervical carcinoma. II. Glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, TPN diaphorase and DPN diaphorase]
Carcinoma
[Is a diagnosis of genital carcinomas by determination of the 6-phosphogluconate dehydrogenase activity of vaginal secretion possible?]
Carcinoma
[Our experience with the glucose-6-phosphate and 6-phosphogluconate dehydrogenase tests in the diagnosis of gynecologic carcinoma]
Carcinoma in Situ
Evaluation of 6-phosphogluconate dehydrogenase in carcinoma in situ of the cervix.
Carcinoma, Hepatocellular
Control of the NADPH supply for oxidative stress handling in cancer cells.
Carcinoma, Hepatocellular
Post-translational regulation of glucose-6-phosphate dehydrogenase activity in (pre)neoplastic lesions in rat liver.
Carcinoma, Hepatocellular
The positive feedback loop between Nrf2 and phosphogluconate dehydrogenase stimulates proliferation and clonogenicity of human hepatoma cells.
Carcinoma, Hepatocellular
Uridine and cytidine nucleotide synthesis in renal hypertrophy: biochemical differences in response to the growth stimulus of diabetes and unilateral nephrectomy.
Carcinoma, Hepatocellular
[Activities of dehydrogenases of the pentose phosphate pathway and transketolase in transplanted mouse hepatomas with different growth rates and in organs of tumor carriers]
Cervical Intraepithelial Neoplasia
Increased activity of 6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase in purified cell suspensions and single cells from the uterine cervix in cervical intraepithelial neoplasia.
Chagas Disease
The 6-phosphogluconate dehydrogenase from Trypanosoma cruzi: the absence of two inter-subunit salt bridges as a reason for enzyme instability.
Chemical and Drug Induced Liver Injury
[Catalytic properties of 6-phosphogluconate dehydrogenase from rat liver in normal state and during toxic hepatitis]
Cysts
A full set of monosomic addition lines in Beta vulgaris from Beta webbiana: morphology and isozyme markers.
Cysts
Some glucose metabolic enzymes in various fractions of sarcocysts of Sarcocystis fusiformis of buffalo (Bubalus bubalis).
Dermatitis, Contact
[Enzymatic activity of the pentosephosphate pathway of carbohydrate conversion in the experimental therapy of dermatitis in rats]
Duodenal Ulcer
[Characteristics of the pentose phosphate pathway of carbohydrate metabolism in the gastric mucosa of persons with peptic ulcer]
Gastrointestinal Stromal Tumors
HIF-1? regulates cellular metabolism, and Imatinib resistance by targeting phosphogluconate dehydrogenase in gastrointestinal stromal tumors.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
Canine malignant hyperthermia susceptibility: erythrocytic defects--osmotic fragility, glucose-6-phosphate dehydrogenase deficiency and abnormal Ca2+ homeostasis.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
The detection of glucose-6-phosphate dehydrogenase deficiency in mediterraneans by comparative quantitative enzyme electrophoresis.
glucose-6-phosphate dehydrogenase (nadp+) deficiency
The Thai variant and the distribution of alleles of 6-phosphogluconate dehydrogenase and the distribution of glucose 6-phosphate dehydrogenase deficiency in Thailand.
Glucosephosphate Dehydrogenase Deficiency
Canine malignant hyperthermia susceptibility: erythrocytic defects--osmotic fragility, glucose-6-phosphate dehydrogenase deficiency and abnormal Ca2+ homeostasis.
Glucosephosphate Dehydrogenase Deficiency
The detection of glucose-6-phosphate dehydrogenase deficiency in mediterraneans by comparative quantitative enzyme electrophoresis.
glutathione-disulfide reductase deficiency
Visual test for erythrocytic glucose-6-phosphate dehydrogenase, 6-phosphogluconic dehydrogenase, and glutathione reductase deficiencies.
Hemoglobinuria
[Hereditary hemolytic anemia associated with insufficient activity of 6-phosphogluconate dehydrogenase of erythrocytes with hemoglobinuria following administration of drugs]
Infections
Cloning, expression and characterization of a cell wall surface protein, 6-phosphogluconate dehydrogenase, of Haemophilus parasuis.
Infections
Cloning, expression and characterization of a cell wall surface protein, 6-phosphogluconate-dehydrogenase, of Streptococcus suis serotype 2.
Infections
Effect of schistosomal infection and its treatment on some key enzymes of glucose metabolism in mice livers.
Infections
Effects of 5,8-dimethylthieno[2,3-b]quinoline-2-carboxylic acid on the antioxidative defense and lipid membranes in Plasmodium berghei-infected erythrocytes.
Infections
Evidence for dimer/tetramer equilibrium in Trypanosoma brucei 6-phosphogluconate dehydrogenase.
Infections
[Glycolysis and pentose-phosphate pathway ratio in staphylococcus from the female genitalia in norm and dysbiosis]
Insulin Resistance
Blunted Reducing Power Generation in Erythrocytes Contributes to Oxidative Stress in Prepubertal Obese Children with Insulin Resistance.
Iron Overload
In vitro and in vivo effects of iron on the expression and activity of glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, and glutathione reductase in rat spleen.
Ketosis
[Glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase activity in animals with experimental ketosis]
Laryngeal Neoplasms
[Activity of the enzymatic antioxidant system depends on the clinical stage of laryngeal cancer ]
Leishmaniasis, Cutaneous
Isoenzyme characterization of Leishmania isolated from human cases with localized cutaneous leishmaniasis from the State of Campeche, Yucatan Peninsula, Mexico.
Leishmaniasis, Cutaneous
[Leishmania infantum Nicolle, 1908, the agent of the autochthonous oriental sore. Apropos of the biochemical identification of 2 strains isolated in the eastern Pyrenees]
Leprosy
Genetic markers and leprosy in South African negroes: Part II. Erythrocyte enzyme polymorphisms.
Leukemia
6-phosphogluconate dehydrogenase: hemizygous manifestation in a patient with leukemia.
Leukemia
Enzyme activities of NADPH-forming metabolic pathways in normal and leukemic leukocytes.
Leukemia
Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin.
Leukemia, Myeloid, Acute
Acute myeloid leukemia cells require 6-phosphogluconate dehydrogenase for cell growth and NADPH-dependent metabolic reprogramming.
Leukemia, Myeloid, Acute
Enzyme activities of NADPH-forming metabolic pathways in normal and leukemic leukocytes.
Lung Neoplasms
Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence.
Lung Neoplasms
Inhibition of 6-phosphogluconate Dehydrogenase Reverses Cisplatin Resistance in Ovarian and Lung Cancer.
Lung Neoplasms
Investigation of the combined action of cisplatin and 6-phosphogluconate dehydrogenase inhibitor on pancreatic and lung cancer cell lines.
Lung Neoplasms
One-step purification of soluble recombinant human 6-phosphogluconate dehydrogenase from Escherichia coli.
Lung Neoplasms
YTH domain family 2 promotes lung cancer cell growth by facilitating 6-phosphogluconate dehydrogenase mRNA translation.
Malaria
An electron cytochemical study of 6-phosphogluconate dehydrogenase activity in infected erythrocytes during malaria.
Malaria
Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target.
Malaria
Studies on enzyme variation in the murine malaria parasites Plasmodium berghei, P. yoelii, P. vinckei and P. chabaudi by starch gel electrophoresis.
Muscular Atrophy
Activities of some antioxidative and hexose monophosphate shunt enzymes of skeletal muscle in neuromuscular diseases.
Muscular Diseases
The inhibitory effect of actinomycin D and cycloheximide on the increase in activity of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in experimentally induced diseased skeletal muscles.
Muscular Diseases
[The activity of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in skeletal muscle tissues of patients with muscular diseases]
Muscular Dystrophy, Duchenne
Changes in some cytoplasmic enzymes from red cells fractionated into age groups by centrifugation in Ficoll/Triosil gradients. Comparison of normal humans and patients with Duchenne muscular dystrophy.
Neoplasm Metastasis
6-Phosphogluconate dehydrogenase fuels multiple aspects of cancer cells: From cancer initiation to metastasis and chemoresistance.
Neoplasm Metastasis
Experimentally induced colon cancer metastases in rat liver increase the proliferation rate and capacity for purine catabolism in liver cells.
Neoplasm Metastasis
Pentose conversions support the tumorigenesis of pancreatic cancer distant metastases.
Neoplasms
1-Hydroxy-8-methoxy-anthraquinon Reverses Cisplatin Resistance by Inhibiting 6PGD in Cancer Cells.
Neoplasms
6-PHOSPHOGLUCONATE DEHYDROGENASE ACTIVITY IN VAGINAL FLUID: LIMITATIONS AS A SCREENING TEST FOR GENITAL CANCER.
Neoplasms
6-Phosphogluconate dehydrogenase fuels multiple aspects of cancer cells: From cancer initiation to metastasis and chemoresistance.
Neoplasms
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Neoplasms
6-Phosphogluconate dehydrogenase regulates tumor cell migration in vitro by regulating receptor tyrosine kinase c-Met.
Neoplasms
6-phosphogluconate dehydrogenase, glucose-6-phosphate dehydrogenase, glucose-6-phosphate isomerase, and hexokinase activity ratios in some human tumor cytosols.
Neoplasms
6PGD Upregulation is Associated with Chemo- and Immuno-Resistance of Renal Cell Carcinoma via AMPK Signaling-Dependent NADPH-Mediated Metabolic Reprograming.
Neoplasms
A modified assay for 6-phosphogluconate dehydrogenase in samples of vaginal fluid from women with and without gynecologic cancer.
Neoplasms
A new enzyme test for gynaecological cancer. 6-Phosphogluconate dehydrogenase activity in vaginal fluid.
Neoplasms
A NEW TEST FOR THE DIAGNOSIS OF GYNAECOLOGICAL CANCER, 6-PHOSPHOGLUCONATE DEHYDROGENASE ACTIVITY IN VAGINAL FLUID.
Neoplasms
Activities of enzymes of the hexose monophosphate pathway in nervous system tumors induced by ethylnitrosourea.
Neoplasms
Calcium Fructoborate Prevents Skin Cancer Development in Balb-c Mice: Next Part, Reverse Inflammation, and Metabolic Alteration.
Neoplasms
Crystal structure of Saccharomyces cerevisiae 6-phosphogluconate dehydrogenase Gnd1.
Neoplasms
Detection of preinvasive and early invasive cancer by 6-phosphogluconate dehydrogenase determinations.
Neoplasms
Enhanced susceptibility to a chemical carcinogen in rats carrying MHC-linked genes influencing development (GRC).
Neoplasms
Evidence for dimer/tetramer equilibrium in Trypanosoma brucei 6-phosphogluconate dehydrogenase.
Neoplasms
Ferroptosis-Related Genes in Lung Adenocarcinoma: Prognostic Signature and Immune, Drug Resistance, Mutation Analysis.
Neoplasms
Fine-needle aspiration of thyroid nodules: proteomic analysis to identify cancer biomarkers.
Neoplasms
Glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase activities in normal canine mammary gland and in mammary tumours and their correlation with oestrogen receptors.
Neoplasms
Glutathione levels and sensitivity to apoptosis are regulated by changes in transaldolase expression.
Neoplasms
Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence.
Neoplasms
HIF-1? regulates cellular metabolism, and Imatinib resistance by targeting phosphogluconate dehydrogenase in gastrointestinal stromal tumors.
Neoplasms
Increased activity of 6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase in purified cell suspensions and single cells from the uterine cervix in cervical intraepithelial neoplasia.
Neoplasms
Influence of insulin on estrogen-induced responses in the r3230ac mammary carcinoma.
Neoplasms
Inhibiting 6-phosphogluconate dehydrogenase selectively targets breast cancer through AMPK activation.
Neoplasms
Inhibition of 6-phosphogluconate dehydrogenase by glucose 1,6-diphosphate in human normal and malignant colon extracts.
Neoplasms
Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth.
Neoplasms
Mitochondrial glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase abrogate p53 induced apoptosis in a yeast model: Possible implications for apoptosis resistance in cancer cells.
Neoplasms
Potential antitumour and pro-oxidative effects of (E)-methyl 2-(7-chloroquinolin-4-ylthio)-3-(4-hydroxyphenyl) acrylate (QNACR).
Neoplasms
The value of 6-phosphogluconate dehydrogenase (6-PGDH) activity as a marker of tumour cellularity and prognostic indicator in primary breast cancer.
Neoplasms
Trial of a simplified vaginal fluid 6-phosphogluconic dehydrogenase assay method in screening for cancer.
Neoplasms
Tyrosine phosphorylation activates 6-phosphogluconate dehydrogenase and promotes tumor growth and radiation resistance.
Neoplasms
Uridine and cytidine nucleotide synthesis in renal hypertrophy: biochemical differences in response to the growth stimulus of diabetes and unilateral nephrectomy.
Neoplasms
Vaginal fluid 6-phosphogluconic dehydrogenase activity in relation to uterine malignancy.
Neoplasms
YTH domain family 2 promotes lung cancer cell growth by facilitating 6-phosphogluconate dehydrogenase mRNA translation.
Neoplasms
[Activities of dehydrogenases of the pentose phosphate pathway and transketolase in transplanted mouse hepatomas with different growth rates and in organs of tumor carriers]
Neuromuscular Diseases
Elevated activity of several antioxidant enzymes in neuromuscular diseases. A histochemical and biochemical study.
Obesity
Dietary soy protein induces hepatic lipogenic enzyme gene expression while suppressing hepatosteatosis in obese female Zucker rats bearing DMBA-initiated mammary tumors.
Osteolysis
Differential proteomic analysis of synovial fluid from hip arthroplasty patients with a pseudotumor vs. Periprosthetic osteolysis?.
Pancreatic Neoplasms
Pancreatic cancers suppress negative feedback of glucose transport to reprogram chromatin for metastasis.
phosphogluconate 2-dehydrogenase deficiency
6-Phosphogluconate dehydrogenase deficiency in an Italian family.
phosphogluconate 2-dehydrogenase deficiency
A NEW INHERITED ENZYMATIC DEFICIENCY OF HUMAN ERYTHROCYTES: 6-PHOSPHOGLUCONATE DEHYDROGENASE DEFICIENCY.
phosphogluconate 2-dehydrogenase deficiency
Erythrocytic glutathione reductase, glucose-6-phosphate dehydrogenase, and 6-phosphogluconic dehydrogenase deficiencies in populations of the United States, South Vietnam, Iran, and Ethiopia.
Primary Myelofibrosis
Blood leucocyte enzymes. II. Activities at 8-9 a.m. in cells of normal subjects, chronic lymphatic leukaemia and chronic myeloid leukaemia patients.
Psoriasis
[Evaluation of the activities of several erythrocyte enzymes (G6PDH, 6PGDH, PHI, aldolase and LDH) in psoriasis]
Starvation
Antimicrobial activity of apple cider vinegar against Escherichia coli, Staphylococcus aureus and Candida albicans; downregulating cytokine and microbial protein expression.
Starvation
Dietary induction of hepatic glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, and malic enzyme in lean and obese female Zucker rats.
Starvation
Expression of glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase isoform genes in suspension-cultured Arabidopsis thaliana cells.
Starvation
Gm6PGDH1, a Cytosolic 6-Phosphogluconate Dehydrogenase, Enhanced Tolerance to Phosphate Starvation by Improving Root System Development and Modifying the Antioxidant System in Soybean.
Starvation
[Intensity of pentose phosphate metabolism of carbohydrates in various brain areas in normal and starved animals]
Stomach Ulcer
[Characteristics of the pentose phosphate pathway of carbohydrate metabolism in the gastric mucosa of persons with peptic ulcer]
Thyroid Carcinoma, Anaplastic
Inhibiting 6-phosphogluconate dehydrogenase reverses doxorubicin resistance in anaplastic thyroid cancer via inhibiting NADPH-dependent metabolic reprogramming.
Trypanosomiasis, African
Aryl phosphoramidates of 5-phospho erythronohydroxamic acid, a new class of potent trypanocidal compounds.
Trypanosomiasis, African
Evidence for dimer/tetramer equilibrium in Trypanosoma brucei 6-phosphogluconate dehydrogenase.
Trypanosomiasis, African
Synthesis and Biological Evaluation of Phosphate Prodrugs of 4-Phospho-D -erythronohydroxamic Acid, an Inhibitor of 6-Phosphogluconate Dehydrogenase.
Trypanosomiasis, African
Synthesis and biological evaluation of substrate-based inhibitors of 6-phosphogluconate dehydrogenase as potential drugs against African trypanosomiasis.
Trypanosomiasis, African
The 6-phosphogluconate dehydrogenase from Trypanosoma cruzi: the absence of two inter-subunit salt bridges as a reason for enzyme instability.
Trypanosomiasis, African
Thermodynamic characterization of substrate and inhibitor binding to Trypanosoma brucei 6-phosphogluconate dehydrogenase.
Trypanosomiasis, African
Virtual fragment screening for novel inhibitors of 6-phosphogluconate dehydrogenase.
Tuberous Sclerosis
Serum and tissue proteins in tuberous sclerosis. I. Serum and red-cell polymorphic systems.
Uterine Cervical Neoplasms
6-PHOSPHOGLUCONATE DEHYDROGENASE ESTIMATION IN VAGINAL FLUID IN THE DIAGNOSIS OF CERVICAL CANCER.
Uterine Cervical Neoplasms
Inhibiting 6-phosphogluconate dehydrogenase enhances chemotherapy efficacy in cervical cancer via AMPK-independent inhibition of RhoA and Rac1.
Uterine Neoplasms
Isoenzymes of hexokinase, 6-phosphogluconate dehydrogenase, phosphoglucomutase and lactate dehydrogenase in uterine cancer.
Uterine Neoplasms
The alleged usefulness of 6-phosphogluconate dehydrogenase determinations in screening for uterine cancer.
Yersinia pseudotuberculosis Infections
GLUCOSE-6-PHOSPHATE DEHYDROGENASE AND 6-PHOSPHOGLUCONATE DEHYDROGENASE ACTIVITIES OF PASTEURELLA PESTIS AND PASTEURELLA PSEUDOTUBERCULOSIS.
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