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Information on EC 1.1.1.299 - malate dehydrogenase [NAD(P)+]

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IUBMB Comments
This enzyme, which was characterized from the methanogenic archaeon Methanobacterium thermoautotrophicum, catalyses only the reduction of oxaloacetate, and can use NAD+ and NADP+ with similar specific activity . Different from EC 1.1.1.37 (malate dehydrogenase (NAD+)), EC 1.1.1.82 (malate dehydrogenase (NADP+)) and EC 1.1.5.4 (malate dehydrogenase (quinone)).
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Word Map
The expected taxonomic range for this enzyme is: Archaea, Bacteria
Synonyms
ldh-like maldh, mdh ii, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(S)-malate + NAD(P)+ = oxaloacetate + NAD(P)H + H+
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PATHWAY SOURCE
PATHWAYS
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