Information on EC 1.1.1.241 - 6-endo-hydroxycineole dehydrogenase

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The expected taxonomic range for this enzyme is: Rhodococcus

EC NUMBER
COMMENTARY hide
1.1.1.241
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RECOMMENDED NAME
GeneOntology No.
6-endo-hydroxycineole dehydrogenase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
6-endo-hydroxycineole + NAD+ = 6-oxocineole + NADH + H+
show the reaction diagram
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
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-
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redox reaction
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-
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reduction
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
1,8-cineole degradation
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Biosynthesis of secondary metabolites
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Monoterpenoid biosynthesis
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SYSTEMATIC NAME
IUBMB Comments
6-endo-hydroxycineole:NAD+ 6-oxidoreductase
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CAS REGISTRY NUMBER
COMMENTARY hide
122933-68-0
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
strain C1
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Manually annotated by BRENDA team
strain C1
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Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
6-endo-hydroxycineole + NAD(P)+
6-oxocineole + NAD(P)H
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
6-endo-hydroxycineole + NAD(P)+
6-oxocineole + NAD(P)H
show the reaction diagram
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
NAD+
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NADH in reverse reaction
NADP+
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NADPH in reverse reaction, 10% of activity over NADH
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.62
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6-endo-hydroxycineole
1.08
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6-oxocineole
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
7.5
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NADH oxidation
10.5
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NAD+ reduction
STORAGE STABILITY
ORGANISM
UNIPROT
LITERATURE
-20°C, after dialysis against 1 mM KH2PO4/Na2HPO4 buffer, pH 7.1
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