Information on EC 1.1.1.167 - hydroxymalonate dehydrogenase

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The expected taxonomic range for this enzyme is: Bombyx mori

EC NUMBER
COMMENTARY hide
1.1.1.167
-
RECOMMENDED NAME
GeneOntology No.
hydroxymalonate dehydrogenase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
hydroxymalonate + NAD+ = oxomalonate + NADH + H+
show the reaction diagram
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
-
-
-
-
redox reaction
-
-
-
-
reduction
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
hydroxymalonate:NAD+ oxidoreductase
-
CAS REGISTRY NUMBER
COMMENTARY hide
58693-60-0
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
silk worm
-
-
Manually annotated by BRENDA team
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
hydroxymalonate + NAD+
oxomalonate + NADH
show the reaction diagram
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
hydroxymalonate + NAD+
oxomalonate + NADH
show the reaction diagram
-
direct correlation between high productive and low productive strains of silk and the amino acid metabolism
-
?
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
NAD+
-
-
SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
high activity
Manually annotated by BRENDA team
-
high activity in fibroin section, lower level of activity in the sericin section
Manually annotated by BRENDA team