2.7.7.9: UTP-glucose-1-phosphate uridylyltransferase

This is an abbreviated version!
For detailed information about UTP-glucose-1-phosphate uridylyltransferase, go to the full flat file.

Reaction

Synonyms

All3274, CugP, cyanobacterial UDP-Glc PPase, ExoN, GalU, gfugp, Glc-1-P UTase, GlcNAc-1-P UTase, glucose 1-phosphate uridylyltransferase, glucose-1-phosphate urididyltransferase, glucose-1-phosphate uridyltransferase, glucose-1-phosphate uridylyltransferase, KF278717, plastid UDP-glucose pyrophosphorylase, rml-1, ScUGPase-1, sll1558, ST0452, ST0452 protein, STK_04520, sugar-1-P NTase, sugar-1-phosphate nucleotidylyltransferase, TaGalU, UDP glucose pyrophosphorylase, UDP-Glc pyrophosphorylase, UDP-GlcPPase, UDP-glucose pyrophosphorylase, UDP-glucose pyrophosphorylase 1, UDP-glucose pyrophosphorylase isoenzyme UGP5, UDP-glucose pyrophosphorylase UGP1, UDP-glucose pyrophosphorylase UGP2, UDP-glucose pyrophosphorylase UGP3, UDPG phosphorylase, UDPG pyrophosphorylase, UDPG-pyrophosphorylase, UDPglucose pyrophosphorylase, UDPGP, UGP, ugp-1, UGP1, UGP3, UgpA, UGPase, UGPase1, UGPase2, UGPG-PPase, UPD1, uridine 5'-diphosphoglucose pyrophosphorylase, uridine diphosphate-D-glucose pyrophosphorylase, uridine diphosphate-glucose pyrophosphorylase, uridine diphosphoglucose pyrophosphorylase, uridine-diphosphate glucose pyrophosphorylase, uridylyltransferase, glucose 1-phosphate, UTP/dTTP-glucose-1-phosphate uridylyl/thymidylyl transferase, UTP:alpha-D-glucose uridylyltransferase, UTP:glucose-1-phosphate uridylyltransferase, VldB

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.7 Nucleotidyltransferases

                2.7.7.9 UTP-glucose-1-phosphate uridylyltransferase

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Results	in table
30	Activating Compound
44477	AA Sequence
7	Application
1	CAS Registry Number
60	Cloned(Commentary)
22	Crystallization (Commentary)
44	Disease/ Diagnostics
6	Expression
56	General Information
10	General Stability
124	Inhibitors
42	kcat/KM [mM/s]
48	Ki Value [mM]
227	KM Value [mM]
42	Localization
173	Metals/Ions
73	Molecular Weight [Da]
64	Natural Substrates/ Products (Substrates)
223	Organism
17	Pathway
87	PDB ID
57	pH Optimum
6	pH Range
9	pH Stability
25	pI Value
3	Posttranslational Modification
122	Protein Variants
73	Purification (Commentary)
25	Reaction
1	Reaction Type
166	Reference
165	Source Tissue
76	Specific Activity [micromol/min/mg]
10	Storage Stability
287	Substrates and Products (Substrate)
69	Subunits
153	Synonyms
1	Systematic Name
33	Temperature Optimum [°C]
3	Temperature Range [°C]
21	Temperature Stability [°C]
72	Turnover Number [1/s]

pH Stability

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pH Stability on EC 2.7.7.9 - UTP-glucose-1-phosphate uridylyltransferase

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pH STABILITY

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

3

Bos taurus

-

4°C, 80% loss of activity immediately

643730

4

Bos taurus

-

4°C, t1/2: 2 days

643730

5

Bos taurus

-

86 days, 4°C, 70% loss of activity

643730

5.8

Oryctolagus cuniculus

-

stable

643733

6 - 8.5

Hordeum vulgare subsp. vulgare

-

47 h, 25°C, 0.1 mg/ml bovine serum albumin, 5% loss of activity. Without bovine serum albumin: 80% or 60% loss of activity within 30 h at pH 6 or pH 6.5, respectively, t1/2: 30 h at pH 7.5 and pH 8.5

643739

6.5 - 7.5

Bos taurus

-

86 days, 4°C, stable

643730

7.5 - 9

Bos taurus

-

30 min, stable at 50°C, in 0.25 M potassium phosphate buffer

643730

7.8

Oryctolagus cuniculus

-

rapid inactivation above

643733

8

Sphingomonas sp. WG

A0A0W1QGK2

the protein remains stable after 1 h at pH 8.0. When the enzyme is incubated in buffer at pH 9.0, more than 50% of the maximum activity is lost

757281