Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.7.7.8: polyribonucleotide nucleotidyltransferase

This is an abbreviated version!
For detailed information about polyribonucleotide nucleotidyltransferase, go to the full flat file.

Word Map on EC 2.7.7.8

Reaction

RNAn+1
+
phosphate
=
RNAn
 +
a nucleoside diphosphate

Synonyms

AtcpPNPase, AtmtPNPase, chloroplast PNPase, cpPNPase, hPNPase(old-35), hPNPaseold-35, nucleoside diphosphate:polynucleotidyl transferase, nucleotidyltransferase, polyribonucleotide, PNP, PNPase, PNPT1, polynucleotide phosphorylase, polyribonucleotide phosphorylase, RNase PH

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.8 polyribonucleotide nucleotidyltransferase

Substrates Products

Substrates Products on EC 2.7.7.8 - polyribonucleotide nucleotidyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2',3'-cyclic RNAn + phosphate
RNA(n-1) + a nucleotide diphosphate
show the reaction diagram
-
-
-
?
24-nucleotide RNA molecule + ADP
25-nucleotide RNA molecule + phosphate
show the reaction diagram
-
when both ADP and phosphate are present at the reaction mixture, the direction of activity, either polyadenylation or degradation, is dependent on their relative concentrations
-
-
r
24-nucleotide RNA molecule + phosphate
23-nucleotide RNA molecule + nucleoside diphosphate
show the reaction diagram
-
when both ADP and phosphate are present at the reaction mixture, the direction of activity, either polyadenylation or degradation, is dependent on their relative concentrations
-
-
r
3'-phosphorylated RNA(n) + phosphate
RNA(n-1) + a nucleotide diphosphate
show the reaction diagram
-
enzyme inefficiently degrades 3'-phosphorylated RNA
-
?
ADP + globin mRNAn
globin mRNAn+1 + phosphate
show the reaction diagram
-
-
-
-
?
microR-221 RNAn+1 + phosphate
microR-221 RNAn + ADP
show the reaction diagram
-
recombinantly expressed microRNAs miR-let7a, miR-106b, miR-25, miR-221, miR-222, and miR-184 as substrates, the recombinant enzyme selectively and preferentially degrades microRNA-221 in human melanoma cells
-
-
r
microRNAn+1 + phosphate
microRNAn + ADP
show the reaction diagram
-
recombinantly expressed microRNAs miR-let7a, miR-106b, miR-25, miR-221, miR-222, and miR-184
-
-
r
pJFD4 HpaI RNA+1 + phosphate
pJFD4 HpaI RNA + nucleoside diphosphate
show the reaction diagram
-
derivative of SP82 phage RNA, arsenate can replace phosphate
-
?
poly(A) + ADP
poly(A)+1 + phosphate
show the reaction diagram
poly(A)(n-1) + ADP
poly(A)n + phosphate
show the reaction diagram
poly(A)+1 + phosphate
poly(A) + ADP
show the reaction diagram
poly(A)n + phosphate
poly(A)(n-1) + ADP
show the reaction diagram
poly(C) + CDP
poly(C)+1 + phosphate
show the reaction diagram
poly(C)+1 + phosphate
poly(C) + ADP
show the reaction diagram
poly(G) + GDP
poly(G)+1 + phosphate
show the reaction diagram
poly(I) + IDP
poly(I)+1 + phosphate
show the reaction diagram
poly(U)+ UDP
poly(U)+1 + phosphate
show the reaction diagram
poly(U)+1 + phosphate
poly(U) + ADP
show the reaction diagram
polyadenylic acid + phosphate
? + ADP
show the reaction diagram
-
-
-
-
?
polycytidylic acid + phosphate
? + CDP
show the reaction diagram
-
-
-
-
?
polyguanylic acid + phosphate
? + GDP
show the reaction diagram
-
-
-
-
?
polyuridylic acid + phosphate
? + UDP
show the reaction diagram
-
-
-
-
?
rabbit globin mRNAn+1 + phosphate
ADP + rabbit globin mRNAn
show the reaction diagram
-
only the poly(A) tail of the mRNA is removed
-
?
ribonucleoside 5'-diphosphate + phosphate
ribonucleoside 5'-diphosphate + phosphate
show the reaction diagram
RNA + ATP
RNA+1 + diphosphate
show the reaction diagram
-
polymerization in the absence of phosphate
-
r
RNA + CTP
RNA+1 + diphosphate
show the reaction diagram
-
polymerization in the absence of phosphate
-
r
RNA + GTP
RNA+1 + diphosphate
show the reaction diagram
-
polymerization in the absence of phosphate
-
r
RNA + UTP
RNA+1 + diphosphate
show the reaction diagram
-
polymerization in the absence of phosphate
-
r
RNA(n) + phosphate
RNA(n-1) + a nucleotide diphosphate
show the reaction diagram
-
-
-
?
RNAn + a nucleoside diphosphate
RNAn+1 + phosphate
show the reaction diagram
RNAn + UDP
RNAn+1 + phosphate
show the reaction diagram
RNAn+1 + phosphate
RNAn + a nucleoside diphosphate
show the reaction diagram
yeast RNA+1 + phosphate
yeast RNA + nucleoside diphosphate
show the reaction diagram
-
2% of activity with poly(U)
-
?
additional information
?
-