2.7.7.53: ATP adenylyltransferase

This is an abbreviated version!
For detailed information about ATP adenylyltransferase, go to the full flat file.

Reaction

Synonyms

5',5'''-P1,P4-tetraphosphate phosphorylase, adenine triphosphate adenylyltransferase, adenylyltransferase, adenine triphosphate, AP-4-A phosphorylase, Ap3A/Ap4A phosphorylase, Ap4A phosphorylase, bis(5'-nucleosyl)-tetraphosphate phosphorylase (NDP-forming), diadenosine 5',5'''-P1,P4-tetraphosphate alpha,beta-phosphorylase, diadenosine 5',5'''-P1,P4-tetraphosphate alpha,beta-phosphorylase (ADP-forming), diadenosine 5',5'''-P1,P4-tetraphosphate alphabeta-phosphorylase (ADP-forming), diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase, diadenosinetetraphosphate alpha,beta-phosphorylase, diadenosinetetraphosphate alphabeta-phosphorylase, dinucleoside oligophosphate alphabeta-phosphorylase, MAV_3489, MEG_2932, Rv2613c

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.7 Nucleotidyltransferases

                2.7.7.53 ATP adenylyltransferase

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Results	in table
908	AA Sequence
1	CAS Registry Number
4	Cloned(Commentary)
1	Crystallization (Commentary)
3	General Information
4	General Stability
21	IC50 Value
62	Inhibitors
5	kcat/KM [mM/s]
3	Ki Value [mM]
32	KM Value [mM]
50	Metals/Ions
12	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
42	Organism
2	Pathway
10	PDB ID
17	pH Optimum
3	pH Range
15	Protein Variants
7	Purification (Commentary)
1	Reaction
1	Reaction Type
30	Reference
10	Specific Activity [micromol/min/mg]
1	Storage Stability
158	Substrates and Products (Substrate)
9	Subunits
32	Synonyms
1	Systematic Name
11	Temperature Optimum [°C]
1	Temperature Stability [°C]
6	Turnover Number [1/s]

KM Value

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KM Value on EC 2.7.7.53 - ATP adenylyltransferase

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KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.31 - 0.7

ADP

2 entries

0.13 - 3

arsenate

2 entries

5.7

ATP

Saccharomyces cerevisiae

-

pH 5.9, 37°C

643508

0.52

chromate

Tetradesmus obliquus

-

P1,P4-bis(5'-adenosyl) tetraphosphate-phosphorolysis, pH 8.0, 25°C

209909

0.7

GDP

Saccharomyces cerevisiae

-

ADP/phosphate-exchange, pH 7.0, 37°C

643510

0.45

molybdate

Tetradesmus obliquus

-

P1,P4-bis(5'-adenosyl) tetraphosphate-phosphorolysis, pH 8.0, 25°C

209909

0.009 - 0.025

P1,P3-bis(5'-adenosyl) triphosphate

2 entries

0.004

P1,P3-bis(5'-adenosyl) triphosphate with CF2-bridge between P1 and P2

Acanthamoeba castellanii

-

pH 8.0, 30°C

289064

0.012

P1,P3-bis(5'-adenosyl) triphosphate with CH2-bridge between P1 and P2

Acanthamoeba castellanii

-

pH 8.0, 30°C

289064

0.0035

P1,P3-bis(5'-adenosyl) triphosphate with CHF-bridge between P1 and P2

Acanthamoeba castellanii

-

pH 8.0, 30°C

289064

0.0053 - 0.11

P1,P4-bis(5'-adenosyl) tetraphosphate

10 entries

0.16 - 2

phosphate

5 entries

1.75

tungstate

Tetradesmus obliquus

-

P1,P4-bis(5'-adenosyl) tetraphosphate-phosphorolysis, pH 8.0, 25°C

209909

0.07

vanadate

Tetradesmus obliquus

-

P1,P4-bis(5'-adenosyl) tetraphosphate-phosphorolysis, pH 8.0, 25°C

209909

additional information

additional information

2 entries

-

0.31

ADP

Saccharomyces cerevisiae

-

pH 5.9, 37°C

643508

0.7

ADP

Saccharomyces cerevisiae

-

ADP/phosphate-exchange, pH 7.0, 37°C

643510

0.13

arsenate

Tetradesmus obliquus

-

P1,P4-bis(5'-adenosyl) tetraphosphate-arsenolysis, pH 7.4, 25°C

209909

3

arsenate

Saccharomyces cerevisiae

-

pH 8.2, 37°C

643507

0.009

P1,P3-bis(5'-adenosyl) triphosphate

Acanthamoeba castellanii

-

pH 8.0, 30°C

289064

0.025

P1,P3-bis(5'-adenosyl) triphosphate

Euglena gracilis

-

-

643513

0.0053

P1,P4-bis(5'-adenosyl) tetraphosphate

Tetradesmus obliquus

-

P1,P4-bis(5'-adenosyl) tetraphosphate-phosphorolysis, pH 8.0, 25°C

209909

0.006

P1,P4-bis(5'-adenosyl) tetraphosphate

Dolichospermum flos-aquae

-

pH 9.5

643515

0.027

P1,P4-bis(5'-adenosyl) tetraphosphate

Euglena gracilis

-

-

643513

0.06

P1,P4-bis(5'-adenosyl) tetraphosphate

Saccharomyces cerevisiae

-

pH 8.2, 37°C

643507

0.07

P1,P4-bis(5'-adenosyl) tetraphosphate

Mycobacterium tuberculosis

P9WMK9

mutant S147A, pH 7.6, 37°C

722980

0.08

P1,P4-bis(5'-adenosyl) tetraphosphate

Mycobacterium tuberculosis

P9WMK9

mutant G146Q, pH 7.6, 37°C

722980

0.08

P1,P4-bis(5'-adenosyl) tetraphosphate

Mycobacterium tuberculosis

P9WMK9

mutant G146S, pH 7.6, 37°C

722980

0.1

P1,P4-bis(5'-adenosyl) tetraphosphate

Mycobacterium tuberculosis

P9WMK9

wild-type, pH 7.6, 37°C

722980

0.1

P1,P4-bis(5'-adenosyl) tetraphosphate

Mycobacterium tuberculosis

P9WMK9

in 50 mM HEPES-Na (pH 7.6), 1 mM MnCl2, at 37°C

713455

0.11

P1,P4-bis(5'-adenosyl) tetraphosphate

Mycobacterium tuberculosis

P9WMK9

mutant S147T, pH 7.6, 37°C

722980

0.16

phosphate

Tetradesmus obliquus

-

P1,P4-bis(5'-adenosyl) tetraphosphate-phosphorolysis, pH 8.0, 25°C

209909

0.5

phosphate

Euglena gracilis

-

-

643513

0.94

phosphate

Mycobacterium tuberculosis

P9WMK9

in 50 mM HEPES-Na (pH 7.6), 1 mM MnCl2, at 37°C

713455

1

phosphate

Saccharomyces cerevisiae

-

pH 8.2, 37°C

643507

2

phosphate

Saccharomyces cerevisiae

-

ADP/phosphate-exchange, pH 7.0, 37°C

643510

additional information

additional information

Saccharomyces cerevisiae

-

-

246767

-

additional information

additional information

Saccharomyces cerevisiae

-

exchange reaction with ADP and analogues

643510

-