2.7.7.5: sulfate adenylyltransferase (ADP)

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For detailed information about sulfate adenylyltransferase (ADP), go to the full flat file.

Reaction

Synonyms

adenosine 5'-phosphosulfate phosphorylase, adenosine diphosphate sulfurylase, adenylylsulfate:phosphate adenylyltransferase, ADP sulfurylase, ADP-sulfurylase, APS phosphorylase, Dcps, Hint4, More, sulfate (adenosine diphosphate) adenylyltransferase

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.7 Nucleotidyltransferases

                2.7.7.5 sulfate adenylyltransferase (ADP)

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Results	in table
1	Activating Compound
11	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
4	General Stability
25	Inhibitors
2	Ki Value [mM]
14	KM Value [mM]
1	Localization
16	Metals/Ions
5	Molecular Weight [Da]
9	Natural Substrates/ Products (Substrates)
11	Organism
6	Pathway
4	pH Optimum
3	pH Range
1	pH Stability
5	Purification (Commentary)
1	Reaction
1	Reaction Type
11	Reference
5	Specific Activity [micromol/min/mg]
1	Storage Stability
39	Substrates and Products (Substrate)
4	Subunits
16	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
7	Temperature Stability [°C]
2	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 2.7.7.5 - sulfate adenylyltransferase (ADP)

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

adenosine 5'-phosphosulfate

Saccharomyces cerevisiae

-

substrate inhibition above 1 mM

643454

ADP

Thiobacillus denitrificans

Q9LA72

-

643459

AMP

Saccharomyces fragilis

-

-

643453

arsenate

2 entries

chromate

Saccharomyces fragilis

-

-

643453

diacetyl

Thiobacillus denitrificans

Q9LA72

slow but complete inactivation

643459

diethyldicarbonate

Thiobacillus denitrificans

Q9LA72

-

643459

F-

Saccharomyces fragilis

-

-

643453

iodoacetamide

Prosthecochloris vibrioformis

-

-

393933

N-ethylmaleimide

2 entries

NaCl

Saccharomyces fragilis

-

slight inhibition

643453

nitrate

Saccharomyces fragilis

-

-

643453

p-chloromercuribenzoate

3 entries

Phenylglyoxal

Thiobacillus denitrificans

Q9LA72

incomplete inactivation

643459

phosphate

3 entries

selenate

Saccharomyces fragilis

-

-

643453

sulfate

2 entries

vanadate

Saccharomyces fragilis

-

-

643453

arsenate

Saccharomyces cerevisiae

-

-

643454

arsenate

Saccharomyces fragilis

-

-

643453

N-ethylmaleimide

Prosthecochloris vibrioformis

-

very potent inhibitor, partially reversible by thiol-containing reagents

393933

N-ethylmaleimide

Saccharomyces cerevisiae

-

-

643454

p-chloromercuribenzoate

Prosthecochloris vibrioformis

-

very potent inhibitor, partially reversible by thiol-containing reagents

393933

p-chloromercuribenzoate

Saccharomyces cerevisiae

-

very potent inhibitor, partially reversible by thiol-containing reagents

643454

p-chloromercuribenzoate

Saccharomyces fragilis

-

-

643453

phosphate

Prosthecochloris vibrioformis

-

above 50 mM

643457

phosphate

Saccharomyces cerevisiae

-

substrate inhibition above 20 mM

643454

phosphate

Saccharomyces cerevisiae

-

competitive

643455

sulfate

Saccharomyces cerevisiae

-

very poor inhibition in combination with increased ionic strength

643455

sulfate

Thiobacillus denitrificans

Q9LA72

inhibitory at high concentrations

643459