2.7.7.46: gentamicin 2''-nucleotidyltransferase

This is an abbreviated version!
For detailed information about gentamicin 2''-nucleotidyltransferase, go to the full flat file.

Word Map on EC 2.7.7.46

2.7.7.46

aac3-ii

tobramycin

colistin

integrons

nucleotidylated

aminoglycoside-modifying

aac6'-ie

aph3\'-vi

amikacin

extended-spectrum

esbls

medicine

theorell-chance

blandm-1

northrop

colistin-resistant

co-harboured

genre

carbapenemases

gentamicin-resistant

netilmicin

Reaction

Synonyms

AAD 2'', aadB, aadB(ant2')Ia, aminoglycoside adenyltransferase 2''-Ia, aminoglycoside adenylyltransferase, aminoglycoside nucleotidyltransferase 2''-I, ANT(2'')-I, ANT(2'')-Ia, ANT2'', gentamicin 2''-adenylyltransferase, gentamicin nucleotidyltransferase

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.7 Nucleotidyltransferases

2.7.7.46 gentamicin 2''-nucleotidyltransferase

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Results	in table
11	AA Sequence
4	Application
1	CAS Registry Number
2	Cloned(Commentary)
2	Expression
1	General Stability
14	Inhibitors
10	Ki Value [mM]
13	KM Value [mM]
2	Localization
6	Metals/Ions
2	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
16	Organism
3	PDB ID
2	pH Optimum
2	pH Range
2	pI Value
3	Protein Variants
4	Purification (Commentary)
2	Reaction
1	Reaction Type
14	Reference
2	Specific Activity [micromol/min/mg]
1	Storage Stability
45	Substrates and Products (Substrate)
2	Subunits
18	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 2.7.7.46 - gentamicin 2''-nucleotidyltransferase

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NTP:gentamicin 2''-nucleotidyltransferase

ATP, dATP, CTP, ITP and GTP can act as donors; kanamycin, tobramycin and sisomicin can also act as acceptors. The nucleotidyl residue is transferred to the 2-hydroxy of the 3-amino-3-deoxy-D-glucose moiety in the antibiotic.