2.7.7.43: N-acylneuraminate cytidylyltransferase

This is an abbreviated version!
For detailed information about N-acylneuraminate cytidylyltransferase, go to the full flat file.

Reaction

Synonyms

AaCSS, acylneuraminate cytidyltransferase, CMAS, Cmas1, Cmas2, CMP sialate pyrophosphorylase, CMP-N-acetylneuraminate synthase, CMP-N-acetylneuraminate synthetase, CMP-N-acetylneuraminic acid synthase, CMP-N-acetylneuraminic acid synthetase, CMP-N-acylneuraminic acid synthetase, CMP-NANA synthetase, CMP-Neu5Ac synthetase, CMP-NeuAc synthetase, CMP-NeuNAc synthetase, CMP-SA synthase, CMP-Sia synthetase, CMP-Sia-syn, CMP-sialate synthase, CMP-sialate synthetase, CMP-sialic acid synthetase, CMP-sialic acid synthetase (CSS), CMP-sialic synthetase, CMPsialate pyrophosphorylase, CMPsialate synthase, CNS, CSAS, CSS, cytidine 5'-monophosphate N-acetylneuraminic acid synthetase, cytidine 5'-monophospho-N-acetylneuraminic acid synthetase, cytidine 5'-monophosphosialic acid synthetase, cytidine 5-monophosphate N-acetylneuraminic acid synthetase, cytidine monophosphate N-acetylneuraminic acid synthetase, cytidine monophosphate sialic acid synthetase, cytidine monophosphate-N-acetylneuraminic acid synthetase, cytidine monophosphate-sialic acid synthetase, cytidine monophospho-sialic acid synthetase, cytidine monophosphoacetylneuraminic synthetase, cytidine monophosphosialate pyrophosphorylase, cytidine monophosphosialate synthetase, cytidyltransferase, acylneuraminate, cytidylyltransferase, acetylneuraminate, DmCSAS, DmCSS, hCSS, mCSS, N-Acetyl-neuraminic acid cytidylyltransferase, NmCSS, SaV CSS, sialate cytidylyltransferase, sialic acid cytidylyltransferase, TcCSS

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.7 Nucleotidyltransferases

                2.7.7.43 N-acylneuraminate cytidylyltransferase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
13	Activating Compound
3864	AA Sequence
8	Application
1	CAS Registry Number
35	Cloned(Commentary)
4	Crystallization (Commentary)
14	Disease/ Diagnostics
1	Expression
12	General Information
9	General Stability
10	IC50 Value
100	Inhibitors
30	kcat/KM [mM/s]
2	Ki Value [mM]
129	KM Value [mM]
30	Localization
64	Metals/Ions
43	Molecular Weight [Da]
37	Natural Substrates/ Products (Substrates)
121	Organism
7	Pathway
17	PDB ID
28	pH Optimum
12	pH Range
3	pH Stability
5	pI Value
8	Posttranslational Modification
53	Protein Variants
26	Purification (Commentary)
6	Reaction
3	Reaction Type
95	Reference
65	Source Tissue
20	Specific Activity [micromol/min/mg]
13	Storage Stability
228	Substrates and Products (Substrate)
39	Subunits
139	Synonyms
1	Systematic Name
21	Temperature Optimum [°C]
6	Temperature Range [°C]
16	Temperature Stability [°C]
44	Turnover Number [1/s]

General Stability

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

General Stability on EC 2.7.7.43 - N-acylneuraminate cytidylyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to General Stability Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

enzyme is stable in lyophilized form

Pelophylax lessonae

-

645265

not stable to freezing and thawing, addition of substrates partially stabilizes the purified enzyme to freezing and thawing

Sus scrofa

-

645255

not stable to lyophilization

Sus scrofa

-

645255

purified enzyme is sensitive to repeated freezing

Rattus norvegicus

-

645261

stability can be improved by 1 mM 2-mercaptoethanol

Pelophylax lessonae

-

645265

stabilized against thermal inactivation by some salts, NaCl, Na2SO4 or Na2HPO4, or by glycerol

Escherichia coli

-

645270

stable in the frozen state, each cycle of freezing and thawing leads to a 15% decrease in activity

Pelophylax lessonae

-

645263

the enzyme is equally stable with or without the presence of glycerol at different temperatures

Acetivibrio thermocellus

-

690583

the enzyme tolerates flash freezing and lyophilization

Streptococcus sp.

-

645257