Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.7.7.41: phosphatidate cytidylyltransferase

This is an abbreviated version!
For detailed information about phosphatidate cytidylyltransferase, go to the full flat file.

Word Map on EC 2.7.7.41

Reaction

CTP
+
phosphatidate
=
diphosphate
+
CDP-diacylglycerol

Synonyms

CarS, CDP diacylglycerol synthase, CDP-DAG synthase, CDP-DG, CDP-DG synthase, CDP-DG synthetase, CDP-diacylglyceride synthetase, CDP-diacylglycerol synthase, CDP-diacylglycerol synthetase, CDP-diglyceride pyrophosphorylase, CDP-diglyceride synthetase, CDPdiglyceride pyrophosphorylase, CDS, CDS1, CDS2, CDS3, Cds4, Cds5, CdsA, CTP-diacylglycerol synthetase, CTP:1,2-diacylglycerophosphate-cytidyl transferase, CTP:phosphatidate cytidylyltransferase, cytidine 5'-diphosphate diacylglycerol synthase, cytidine diphosphoglyceride pyrophosphorylase, cytidinediphosphate diacylglycerol synthase, cytidylyltransferase, phosphatidate, DAG synthetase, More, phosphatidate cytidyltransferase, phosphatidate cytidyltransferase 2, phosphatidic acid cytidylyltransferase, SJAG_00426, Tam41, TAMM41, Tb927.7.220, TbCDS, YnbD

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.41 phosphatidate cytidylyltransferase

Activating Compound

Activating Compound on EC 2.7.7.41 - phosphatidate cytidylyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
bovine serum albumin
-
activity is 6fold increased
-
cationic detergent
-
the phosphatidate must be emulsified in a cationic detergent for optimal activity
-
CHAPS
-
maximal activity at 0.5%
Cutsum
Micrococcus cerificans
-
enhances activity
-
ITP
-
stimulates only in presence of either lecithin or sphingomyelin
lecithin
-
stimulates
non-ionic detergent
-
Norfenfluramine
-
can partially replace the divalent cation requirement
phosphatidylcholine
-
the solubilized but not the microsomal enzyme is activated
sphingomyelin
-
stimulates
Triton X-100
UTP
-
stimulates only in presence of either lecithin or sphingomyelin