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2.7.7.31: DNA nucleotidylexotransferase

This is an abbreviated version!
For detailed information about DNA nucleotidylexotransferase, go to the full flat file.

Word Map on EC 2.7.7.31

Reaction

a 2'-deoxyribonucleoside 5'-triphosphate
+
DNAn
=
diphosphate
+
DNAn+1

Synonyms

addase, bTdT, deoxynucleotidyl terminal transferase, deoxynucleotidyl transferase, deoxyribonucleic acid nucleotidyltransferase, deoxyribonucleic nucleotidyltransferase, DNA-polymerizing enzyme, DNTT, hTdT, hTdTL1, hTdTL2, hTdTS, mTdT, nucleotidyltransferase, terminal deoxyribo-, Rep75, TdT, terminal addition enzyme, terminal deoxynucleotide transferase, terminal deoxynucleotidyl transferase, terminal deoxynucleotidyl transferase (TDT), terminal deoxynucleotidyltransferase, terminal deoxynucleotiyl transferase, terminal deoxyribonucleotidyl transferase, terminal deoxyribonucleotidyltransferase

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.31 DNA nucleotidylexotransferase

IC50 Value

IC50 Value on EC 2.7.7.31 - DNA nucleotidylexotransferase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0055
5-(hydroxymethyl)-2-furfural
Bos taurus
-
-
0.0472
6-(1-phenyl-1H-indol-3-yl)-2,4-dioxy-5-hexenoic acid
Bos taurus
-
IC50: 0.0472 mM
0.0079
6-(1-phenylmethyl-1H-indol-3-yl)-2,4-dioxy-5-hexenoic acid
Bos taurus
-
IC50: 0.0079 mM
0.0162
6-(4-benzoyl-1-phenylmethyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acid
Bos taurus
-
IC50: 0.0162 mM
0.00053
aurintricarboxylic acid
Homo sapiens
-
at pH 7.2 and 37°C
0.0186
Baicalin
Homo sapiens
-
competitive versus the DNA primer and non-competitive versus the dNTP substrate, IC50: 0.0186 mM
0.144
diallyl trisulfide
Bos taurus
-
at 37°C
1.27
diphosphate
Homo sapiens
-
at pH 7.2 and 37°C
0.0287
genistein
Homo sapiens
-
competitive versus the DNA primer and non-competitive versus the dNTP substrate, IC50: 0.0287 mM