2.7.7.3: pantetheine-phosphate adenylyltransferase

This is an abbreviated version!
For detailed information about pantetheine-phosphate adenylyltransferase, go to the full flat file.

Word Map on EC 2.7.7.3

2.7.7.3

ppats

penultimate

dpcoa

pantothen

pyrophosphate

hexameric

3\'-dephospho-coa

nucleotidyltransferase

dephosphocoenzyme

phosphopantothenoylcysteine

medicine

drug development

Reaction

Synonyms

3'-dephospho-CoA pyrophosphorylase, 4'-phosphopantetheine adenylyltransferase, 4-phosphopantetheine adenylyltransferase, CoaD, dephospho-CoA pyrophosphorylase, dephospho-coenzyme A pyrophosphorylase, Enterococcus faecalis PPAT, More, pantetheine phosphate adenylyltransferase, phosphopantetheine adenylyltransferase, PPAT

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.7 Nucleotidyltransferases

2.7.7.3 pantetheine-phosphate adenylyltransferase

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Results	in table
4	Activating Compound
39402	AA Sequence
5	Application
1	CAS Registry Number
27	Cloned(Commentary)
25	Crystallization (Commentary)
15	Disease/ Diagnostics
18	General Information
70	IC50 Value
115	Inhibitors
12	Ki Value [mM]
25	KM Value [mM]
20	Localization
12	Metals/Ions
22	Molecular Weight [Da]
42	Natural Substrates/ Products (Substrates)
194	Organism
7	Pathway
261	PDB ID
15	pH Optimum
3	pH Stability
1	pI Value
13	Protein Variants
27	Purification (Commentary)
1	Reaction
2	Reaction Type
77	Reference
16	Source Tissue
7	Specific Activity [micromol/min/mg]
1	Storage Stability
80	Substrates and Products (Substrate)
31	Subunits
81	Synonyms
1	Systematic Name
19	Temperature Optimum [°C]
3	Temperature Stability [°C]
4	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 2.7.7.3 - pantetheine-phosphate adenylyltransferase

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2'-deoxy-ATP + pantetheine 4'-phosphate

Corynebacterium ammoniagenes

phosphorylation at 27% the rate of ATP

643183

4'-phosphopantetheine + ATP

3'-dephospho-CoA + diphosphate

2 entries

4'-phosphopantetheine + Mg2+-ATP

3'-dephospho-CoA + diphosphate

Arabidopsis thaliana

PPAT does not accept 4'-phosphopantothenoyl-Cys as a substrate

694729

ATP + 4'-phosphopantetheine

diphosphate + 3'-dephospho-CoA

Staphylococcus aureus

P63819

701543

ATP + pantetheine 4'-phosphate

diphosphate + 3'-dephospho-CoA

54 entries

diphosphate + 3'-dephospho-CoA

ATP + pantetheine 4'-phosphate

4 entries

phosphopantetheine + Mg-ATP

dephospho-CoA + diphosphate

2 entries

phosphopantetheine + MgATP2- + 4 H+

dephospho-CoA + diphosphate + Mg2+

Escherichia coli

coenzyme A (CoA) biosynthesis

674344