2.7.7.24: glucose-1-phosphate thymidylyltransferase
This is an abbreviated version!
For detailed information about glucose-1-phosphate thymidylyltransferase, go to the full flat file.
Word Map on EC 2.7.7.24
-
2.7.7.24
-
l-rhamnose
-
dtdp-l-rhamnose
-
4,6-dehydratase
-
deoxysugars
-
uridylyltransferase
-
dtdp-4-keto-6-deoxy-d-glucose
-
3,5-epimerase
-
deoxyhexose
-
dtmp
-
analysis
-
medicine
- 2.7.7.24
- l-rhamnose
- dtdp-l-rhamnose
-
4,6-dehydratase
-
deoxysugars
-
uridylyltransferase
- dtdp-4-keto-6-deoxy-d-glucose
-
3,5-epimerase
-
deoxyhexose
- dtmp
- analysis
- medicine
Reaction
Synonyms
Cps23FL, Cps2L, D-glucose-1-phosphate thymidylyltransferase, DnmL, dTDP-alpha-D-glucose pyrophosphorylase, dTDP-D-glucose synthase, dTDP-glucose synthase, dTDP-glucose-pyrophosphorylase, dTDPglucose pyrophosphorylase, Glc-1-P thymidylyltransferase, Glc-1-P TTase, Glc-1-P-TT, Glc1P-thymidylyltransferase, glucose 1-phosphate thymidylyltransferase, glucose-1-phosphate thymidylyltransferase, RfbA, rml-1, RmlA, RmlA protein, SchS6, SgcA1, ST0452, sugar-1-phosphate nucleotidyltransferase, TDP-glucose pyrophosphorylase, thymidine diphosphate glucose pyrophosphorylase, thymidine diphosphoglucose pyrophosphorylase, thymidylyltransferase, glucose 1-phosphate, ugpG, UgpG protein, UTP/dTTP-glucose-1-phosphate uridylyl/thymidylyl transferase
ECTree
2.7.7.24 glucose-1-phosphate thymidylyltransferaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 2.7.7.24 - glucose-1-phosphate thymidylyltransferase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
dATP + alpha-D-glucosamine 1-phosphate
diphosphate + dADP-alpha-D-glucosamine
-
21% yield with 0.06 mM enzyme
-
-
?
dCTP + alpha-D-glucose 1-phosphate
diphosphate + dCDP-alpha-D-glucose
-
35% yield with 0.006 mM enzyme, 87% yield with 0.06 mM enzyme
-
-
?
deoxythymidine 5'-tetraphosphate + alpha-D-glucose 1-phosphate
triphosphate + dTDP-alpha-D-glucose
-
-
alternative products dTTP-alpha-D-glucose and diphosphate are not detected
-
?
dGTP + alpha-D-glucose 1-phosphate
diphosphate + dGDP-alpha-D-glucose
-
53% yield with 0.006 mM enzyme, 89% yield with 0.06 mM enzyme
-
-
?
diphosphate + dTDP-alpha-D-glucose
dTTP + alpha-D-glucose 1-phosphate
-
-
-
r
dTTP + 2-deoxy-2-amino-alpha-D-glucose 1-phosphate
diphosphate + dTDP-2-deoxy-2-amino-alpha-D-glucose
-
-
-
-
?
dTTP + 3-deoxy-3-amino-alpha-D-glucose 1-phosphate
diphosphate + dTDP-3-deoxy-3-amino-alpha-D-glucose
-
-
-
-
?
dTTP + 3-deoxy-3-azido-alpha-D-glucose 1-phosphate
diphosphate + dTDP-3-deoxy-3-azido-alpha-D-glucose
-
-
-
-
?
dTTP + alpha-D-galactosamine 1-phosphate
diphosphate + dTDP-alpha-D-galactosamine
-
5% yield with 0.06 mM enzyme
-
-
?
dTTP + alpha-D-galactose 1-phosphate
diphosphate + dTDP-alpha-D-galactose
-
91% yield with 0.06 mM enzyme
-
-
?
dTTP + alpha-D-galactose-1-phosphate
dTDP-galactose + diphosphate
10% of the activity with dTTP and alpha-D-glucose 1-phosphate
-
-
?
dTTP + alpha-D-glucosamine 1-phosphate
diphosphate + dTDP-alpha-D-glucosamine
-
71% yield with 0.06 mM enzyme
-
-
?
dTTP + alpha-D-glucosamine 1-phosphate
dTDP-glucosamine + diphosphate
23% activity compared to alpha-D-glucose 1-phosphate
-
-
r
dTTP + alpha-D-glucosamine-1-phosphate
dTDP-glucosamine + diphosphate
23% of the activity with dTTP and alpha-D-glucose 1-phosphate
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-glucose
-
-
-
-
?
dTTP + alpha-D-mannose 1-phosphate
diphosphate + dTDP-alpha-D-mannose
-
88% yield with 0.06 mM enzyme
-
-
?
dTTP + alpha-D-mannose 1-phosphate
dTDP-mannose + diphosphate
11% activity compared to alpha-D-glucose 1-phosphate
-
-
r
dTTP + alpha-D-mannose-1-phosphate
dTDP-mannose + diphosphate
11% of the activity with dTTP and alpha-D-glucose 1-phosphate
-
-
?
dTTP + [[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]methyl]phosphonic acid
diphosphate + dTDP-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]methyl]phosphonic acid
-
-
-
-
?
dUTP + alpha-D-galactose 1-phosphate
diphosphate + dUDP-alpha-D-galactose
-
83% yield with 0.06 mM enzyme
-
-
?
dUTP + alpha-D-glucose 1-phosphate
diphosphate + dUDP-alpha-D-glucose
-
88% yield with 0.006 mM enzyme, 95% yield with 0.06 mM enzyme
-
-
?
GTP + alpha-D-glucose 1-phosphate
GDP-glucose + diphosphate
Salmonella enterica typhimurium
-
-
-
-
?
GTP + alpha-D-mannose 1-phosphate
diphosphate + GDP-alpha-D-mannose
-
13% yield with 0.06 mM enzyme
-
-
?
UTP + 2-deoxy-2-amino-alpha-D-glucose 1-phosphate
diphosphate + UDP-2-deoxy-2-amino-alpha-D-glucose
-
-
-
-
?
UTP + alpha-D-galactose 1-phosphate
diphosphate + UDP-alpha-D-galactose
-
86% yield with 0.06 mM enzyme
-
-
?
UTP + alpha-D-glucosamine 1-phosphate
diphosphate + UDP-alpha-D-glucosamine
-
12% yield with 0.06 mM enzyme
-
-
?
UTP + alpha-D-glucosamine 1-phosphate
UDP-glucosamine + diphosphate
8% activity compared to the reaction with alpha-D-glucose 1-phosphate and dTTP
-
-
r
UTP + alpha-D-glucosamine-1-phosphate
UDP-glucosamine + diphosphate
8% of the activity with dTTP and alpha-D-glucose 1-phosphate
-
-
?
UTP + alpha-D-glucose-1-phosphate
UDP-glucose + diphosphate
12% of the activity with dTTP and alpha-D-glucose 1-phosphate
-
-
?
UTP + alpha-D-mannose 1-phosphate
diphosphate + UDP-alpha-D-mannose
-
78% yield with 0.06 mM enzyme
-
-
?
UTP + [[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]methyl]phosphonic acid
diphosphate + UMP-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]methyl]phosphonic acid
-
-
-
-
?
ATP + alpha-D-glucose 1-phosphate
ADP-glucose + diphosphate
Salmonella enterica typhimurium
-
-
-
-
?
ATP + alpha-D-glucose 1-phosphate
ADP-glucose + diphosphate
1% activity compared to dTTP
-
-
r
ATP + alpha-D-glucose 1-phosphate
ADP-glucose + diphosphate
1% activity compared to dTTP
-
-
r
ATP + alpha-D-glucose 1-phosphate
diphosphate + ADP-alpha-D-glucose
RML-1 demonstrates a broad substrate range toward five nucleotides (dTTP, UTP, CTP, ATP and GTP) in the presence of alpha-D-glucose 1-phosphate, with higher activity toward dTTP and UTP
-
-
?
ATP + alpha-D-glucose 1-phosphate
diphosphate + ADP-alpha-D-glucose
-
-
-
-
?
ATP + alpha-D-glucose 1-phosphate
diphosphate + ADP-alpha-D-glucose
-
13% yield with 0.006 mM enzyme, 78% yield with 0.06 mM enzyme
-
-
?
ATP + alpha-D-glucose-1-phosphate
ADP-glucose + diphosphate
1.0% of the activity with dTTP and alpha-D-glucose 1-phosphate
-
-
?
ATP + alpha-D-glucose-1-phosphate
ADP-glucose + diphosphate
1.0% of the activity with dTTP and alpha-D-glucose 1-phosphate
-
-
?
CTP + alpha-D-glucose 1-phosphate
CDP-glucose + diphosphate
Salmonella enterica typhimurium
-
-
-
-
?
CTP + alpha-D-glucose 1-phosphate
CDP-glucose + diphosphate
1.2% activity compared to dTTP
-
-
r
CTP + alpha-D-glucose 1-phosphate
diphosphate + CDP-alpha-D-glucose
RML-1 demonstrates a broad substrate range toward five nucleotides (dTTP, UTP, CTP, ATP and GTP) in the presence of alpha-D-glucose 1-phosphate, with higher activity toward dTTP and UTP
-
-
?
CTP + alpha-D-glucose 1-phosphate
diphosphate + CDP-alpha-D-glucose
-
-
-
-
?
CTP + alpha-D-glucose-1-phosphate
CDP-glucose + diphosphate
1.2% of the activity with dTTP and alpha-D-glucose 1-phosphate
-
-
?
CTP + alpha-D-glucose-1-phosphate
CDP-glucose + diphosphate
1.2% of the activity with dTTP and alpha-D-glucose 1-phosphate
-
-
?
dATP + alpha-D-glucose 1-phosphate
dADP-glucose + diphosphate
Salmonella enterica typhimurium
-
-
-
-
?
dATP + alpha-D-glucose 1-phosphate
dADP-glucose + diphosphate
Salmonella enterica typhimurium LT2
-
-
-
-
?
dCTP + alpha-D-glucose 1-phosphate
dCDP-glucose + diphosphate
Salmonella enterica typhimurium
-
-
-
-
?
dCTP + alpha-D-glucose 1-phosphate
dCDP-glucose + diphosphate
Salmonella enterica typhimurium LT2
-
-
-
-
?
dGTP + alpha-D-glucose 1-phosphate
dGDP-glucose + diphosphate
Salmonella enterica typhimurium
-
-
-
-
?
dGTP + alpha-D-glucose 1-phosphate
dGDP-glucose + diphosphate
Salmonella enterica typhimurium LT2
-
-
-
-
?
dTDP-glucose + diphosphate
dTTP + alpha-D-glucose 1-phosphate
-
protein by ugpG gene is involved in gellan gum biosynthesis and exhibits both dTDP- and UDP-glucose diphosphorylase activities
-
-
?
dTDP-glucose + diphosphate
dTTP + alpha-D-glucose 1-phosphate
-
protein encoded by rmlA gene is involved in gellan gum biosynthesis and exhibits both dTDP- and UDP-glucose diphosphorylase activities
-
-
?
dTTP + alpha-D-galactose 1-phosphate
dTDP-galactose + diphosphate
-
12.6% of the activity with alpha-D-glucose 1-phosphate
-
-
?
dTTP + alpha-D-galactose 1-phosphate
dTDP-galactose + diphosphate
10% activity compared to alpha-D-glucose 1-phosphate
-
-
r
dTTP + alpha-D-galactose 1-phosphate
dTDP-galactose + diphosphate
-
12.6% of the activity with alpha-D-glucose 1-phosphate
-
-
?
dTTP + alpha-D-galactose 1-phosphate
dTDP-galactose + diphosphate
10% activity compared to alpha-D-glucose 1-phosphate
-
-
r
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
RML-1 demonstrates a broad substrate range toward five nucleotides (dTTP, UTP, CTP, ATP and GTP) in the presence of alpha-D-glucose 1-phosphate, with higher activity toward dTTP and UTP
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
the enzyme is involved in the biosynthesis of the dTDP-3-amino-3,6-dideoxy-D-galactose and dTDP-3-amino-3,6-dideoxy-D-glucose
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
-
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
-
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
-
86% yield with 0.006 mM enzyme, 93% yield with 0.06 mM enzyme
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
-
-
-
r
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
maximal velocity of the reverse reaction is 11.4fold of the maximal velocity of the forward reaction. The multifunctional enzyme also shows activity with UTP + alpha-D-glucose 1-phosphate (EC 2.7.7.9, UTP-glucose-1-phosphate uridylyltransferase), UTP + N-acetylglucosamine 1-phosphate (EC 2.7.7.23, UDP-N-acetylglucosamine diphosphorylase), dTTP + N-acetylglucosamine 1-phosphate (N-acetylglucosamine 1-phosphate thymidylyltransferase), dCTP + alpha-D-glucose 1-phosphate (glucose-1-phosphate cytidylyltransferase), dGTP + alpha-D-glucose 1-phosphate (glucose-1-phosphate guanylyltransferase), dATP + alpha-D-glucose 1-phosphate (glucose-1-phosphate adenylyltransferase). No activity with: alpha-D-glucose 1-phosphate + dATP, alpha-D-glucose 1-phosphate + dCTP, alpha-D-glucose 1-phosphate + dGTP, UTP + alpha-D-mannose1-phosphate, UTP + alpha-D-galactose 1-phosphate, UTP + alpha-D-glucosamine 1-phosphate
-
-
r
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
the enzyme also shows activity of EC 2.7.7.23, UDP-N-acetylglucosamine diphosphorylase
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
the enzyme is involved in biosynthesis of L-rhamnose
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
maximal velocity of the reverse reaction is 11.4fold of the maximal velocity of the forward reaction. The multifunctional enzyme also shows activity with UTP + alpha-D-glucose 1-phosphate (EC 2.7.7.9, UTP-glucose-1-phosphate uridylyltransferase), UTP + N-acetylglucosamine 1-phosphate (EC 2.7.7.23, UDP-N-acetylglucosamine diphosphorylase), dTTP + N-acetylglucosamine 1-phosphate (N-acetylglucosamine 1-phosphate thymidylyltransferase), dCTP + alpha-D-glucose 1-phosphate (glucose-1-phosphate cytidylyltransferase), dGTP + alpha-D-glucose 1-phosphate (glucose-1-phosphate guanylyltransferase), dATP + alpha-D-glucose 1-phosphate (glucose-1-phosphate adenylyltransferase). No activity with: alpha-D-glucose 1-phosphate + dATP, alpha-D-glucose 1-phosphate + dCTP, alpha-D-glucose 1-phosphate + dGTP, UTP + alpha-D-mannose1-phosphate, UTP + alpha-D-galactose 1-phosphate, UTP + alpha-D-glucosamine 1-phosphate
-
-
r
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
the enzyme also shows activity of EC 2.7.7.23, UDP-N-acetylglucosamine diphosphorylase
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
diphosphate + dTDP-alpha-D-glucose
-
-
-
r
dTTP + alpha-D-glucose 1-phosphate
dTDP-alpha-D-glucose + diphosphate
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
dTDP-alpha-D-glucose + diphosphate
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
-
-
-
r
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
probably involved in conversion of D-glucose to L-rhamnose in the biosynthesis of deoxy compound
-
-
?
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
-
-
-
r
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
Mycolicibacterium smegmatis mc(2)155 / ATCC 700084
-
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
-
-
-
r
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
first enzyme of the dTDP-L-rhamnose synthesis pathway
-
-
?
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
Salmonella enterica typhimurium
-
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
Salmonella enterica typhimurium LT2
-
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
Streptococcus zymogenes
-
-
-
-
?
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
-
-
-
r
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
-
-
-
r
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
sequential mechanism
-
-
?
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
the enzyme catalyzes the first step in the biosynthesis of 4-deoxy-4-(dimethylamino)-5,5-dimethyl-D-ribopyranose moiety
-
-
?
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
highly specific for dTDP-glucose and diphosphate
-
r
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
100% activity
-
-
r
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
in the opposite direction the enzyme is highly specific for dTDP-D-glucose and diphosphate
-
-
r
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
in the opposite direction the enzyme is highly specific for dTDP-D-glucose and diphosphate
-
-
r
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
highly specific for dTDP-glucose and diphosphate
-
r
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
100% activity
-
-
r
dTTP + alpha-D-glucose 1-phosphate
dTDP-glucose + diphosphate
-
-
-
?
GTP + alpha-D-glucose 1-phosphate
diphosphate + GDP-alpha-D-glucose
RML-1 demonstrates a broad substrate range toward five nucleotides (dTTP, UTP, CTP, ATP and GTP) in the presence of alpha-D-glucose 1-phosphate, with higher activity toward dTTP and UTP
-
-
?
GTP + alpha-D-glucose 1-phosphate
diphosphate + GDP-alpha-D-glucose
-
-
-
-
?
GTP + alpha-D-glucose 1-phosphate
diphosphate + GDP-alpha-D-glucose
-
no product yield with 0.006 mM enzyme, 91% yield with 0.06 mM enzyme
-
-
?
UTP + alpha-D-glucose 1-phosphate
diphosphate + UDP-alpha-D-glucose
-
-
-
?
UTP + alpha-D-glucose 1-phosphate
diphosphate + UDP-alpha-D-glucose
RML-1 demonstrates a broad substrate range toward five nucleotides (dTTP, UTP, CTP, ATP and GTP) in the presence of alpha-D-glucose 1-phosphate, with higher activity toward dTTP and UTP
-
-
?
UTP + alpha-D-glucose 1-phosphate
diphosphate + UDP-alpha-D-glucose
-
-
-
-
?
UTP + alpha-D-glucose 1-phosphate
diphosphate + UDP-alpha-D-glucose
-
-
-
-
?
UTP + alpha-D-glucose 1-phosphate
diphosphate + UDP-alpha-D-glucose
-
40% yield with 0.006 mM enzyme, 94% yield with 0.06 mM enzyme
-
-
?
UTP + alpha-D-glucose 1-phosphate
UDP-glucose + diphosphate
Salmonella enterica typhimurium
-
-
-
-
?
UTP + alpha-D-glucose 1-phosphate
UDP-glucose + diphosphate
-
5.5% of the activity with dTTP
-
-
?
UTP + alpha-D-glucose 1-phosphate
UDP-glucose + diphosphate
12% activity compared to dTTP
-
-
r
UTP + alpha-D-glucose 1-phosphate
UDP-glucose + diphosphate
-
5.5% of the activity with dTTP
-
-
?
UTP + alpha-D-glucose 1-phosphate
UDP-glucose + diphosphate
12% activity compared to dTTP
-
-
r
additional information
?
-
Salmonella enterica typhimurium
-
utilizes all eight naturally occurring NTPs with varying levels of catalytic efficiency, even in the presence of nonnative sugar-1-phosphates
-
-
?
additional information
?
-
Salmonella enterica typhimurium LT2
-
utilizes all eight naturally occurring NTPs with varying levels of catalytic efficiency, even in the presence of nonnative sugar-1-phosphates
-
-
?
additional information
?
-
-
no activity with alpha-D-galacturonic acid 1-phosphate
-
-
-
additional information
?
-
-
GTP, UTP/alpha-D-mannose-1-phosphate or UTP/alpha-D-galactose-1-phosphate are no substrates
-
-
?
additional information
?
-
GTP, UTP/alpha-D-mannose-1-phosphate or UTP/alpha-D-galactose-1-phosphate are no substrates
-
-
?
additional information
?
-
-
the enzyme shows 102% relative activity for dTMP or dTDP compared to dTTP at 2 mM, respectively
-
-
?
additional information
?
-
the enzyme shows 102% relative activity for dTMP or dTDP compared to dTTP at 2 mM, respectively
-
-
?
additional information
?
-
-
almost no activity with ATP-D-glucose, CTP-D-glucose, UTP-D-Glucose, GTP, alpha-D-galactose-1-phosphate, and alpha-D-mannose-1-phosphate
-
-
?
additional information
?
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almost no activity with ATP-D-glucose, CTP-D-glucose, UTP-D-Glucose, GTP, alpha-D-galactose-1-phosphate, and alpha-D-mannose-1-phosphate
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-
?
additional information
?
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GTP, UTP/alpha-D-mannose-1-phosphate or UTP/alpha-D-galactose-1-phosphate are no substrates
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-
?
additional information
?
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GTP, UTP/alpha-D-mannose-1-phosphate or UTP/alpha-D-galactose-1-phosphate are no substrates
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-
?
additional information
?
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the enzyme shows 102% relative activity for dTMP or dTDP compared to dTTP at 2 mM, respectively
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?
additional information
?
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the enzyme shows 102% relative activity for dTMP or dTDP compared to dTTP at 2 mM, respectively
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-
?
additional information
?
-
-
almost no activity with ATP-D-glucose, CTP-D-glucose, UTP-D-Glucose, GTP, alpha-D-galactose-1-phosphate, and alpha-D-mannose-1-phosphate
-
-
?
additional information
?
-
almost no activity with ATP-D-glucose, CTP-D-glucose, UTP-D-Glucose, GTP, alpha-D-galactose-1-phosphate, and alpha-D-mannose-1-phosphate
-
-
?
additional information
?
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the multifunctional enzyme is involved in biosynthesis of UDP-N-acetyl-alpha-D-glucosamine, an activated and essential form of N-acetyl-alpha-D-glucosamine that is an important component in the polysaccharide structure of most organisms
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?
additional information
?
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the multifunctional enzyme is involved in biosynthesis of UDP-N-acetyl-alpha-D-glucosamine, an activated and essential form of N-acetyl-alpha-D-glucosamine that is an important component in the polysaccharide structure of most organisms
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?
