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2.7.7.15: choline-phosphate cytidylyltransferase

This is an abbreviated version!
For detailed information about choline-phosphate cytidylyltransferase, go to the full flat file.

Word Map on EC 2.7.7.15

Reaction

CTP
+
phosphocholine
=
diphosphate
 +
CDP-choline

Synonyms

AtCCT1, CCT, CCT-alpha, CCT1, CCT2, CCTalpha, CCTalpha236, CCTbeta, CCTbeta2, CCTbeta3, CDP-choline pyrophosphorylase, CDP-choline synthetase, choline phosphate cytidylyltransferase, choline-phosphate cytidylyltransferase A, choline-phosphate cytidylyltransferase-alpha, cholinephosphate cytidylyltransferase, CpCCT1, cpcT, CTalpha, CTbeta2, CTP-phosphocholine cytidylyltransferase, CTP:cholinephosphate cytidylyltransferase, CTP:phosphocholine cytidylyltransferase, CTP:phosphocholine cytidylyltransferase alpha, CTP:phosphocholine cytidylyltransferase alpha-isoform, CTP:phosphocholine cytidylyltransferase beta2, CTP:phosphocholine cytidylyltransferase beta3, CTP:phosphocholine cytidylyltransferase CCT, CTP:phosphocholine cytidylyltransferase-alpha, CTP:phosphocholine cytidylyltransferase-beta2, CTP:phosphocholine cytidylyltranspherase alpha, CTP:phosphorylcholine cytidylyltransferase, CTP:phosphorylcholine cytidylyltransferase CCT1, CTP:phosphorylcholine cytidylyltransferase CCT2, cytidine diphosphocholine pyrophosphorylase, cytidylyltransferase, cytidylyltransferase, choline phosphate, LmjF.18.1330, More, PCYT1A, PF3D7_1316600, PfCCT, phosphocholine cytidylyltransferase, phosphocholine cytidylyltransferase alpha, phosphorylcholine cytidylyltransferase, phosphorylcholine transferase, phosphorylcholine:CTP cytidylyltransferase

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.15 choline-phosphate cytidylyltransferase

Specific Activity

Specific Activity on EC 2.7.7.15 - choline-phosphate cytidylyltransferase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.00296
-
L-form
0.0048
-
cell extract
0.021
H168A/Y173A mutant deletion construct 1-236, variable CTP concentration, 1.5 mM choline phosphate
0.025
-
H-form
0.034
H168A mutant deletion construct 1-236, variable CTP concentration, 1.5 mM choline phosphate
0.055
H168A/Y173A mutant deletion construct 1-236, variable choline phosphate concentration, 8.8 mM CTP
0.069
H168A mutant deletion construct 1-236, variable choline phosphate concentration, 8.8 mM CTP
0.1096
-
-
0.116
Y173A mutant deletion construct 1-236, variable choline phosphate concentration, 8.8 mM CTP
0.167
Y173A mutant deletion construct 1-236, variable CTP concentration, 1.5 mM choline phosphate
0.35
-
with phosphoethanolamine as substrate
1.724
wild-type deletion construct 1-236, variable choline phosphate concentration, 8.8 mM CTP
10
wild-type protein in the presence of 0.01 mM phosphatidylcholine:oleate
10.7
-
with phosphocholine as substrate
16.12
-
with phosphodimethylethanolamine as substrate
3.399
wild-type deletion construct 1-236, variable CTP concentration, 1.5 mM choline phosphate
3.45
-
with phosphomonomethylethanolamine as substrate
3.85
-
truncated enzyme mutant CCTalpha236, pH 7.0,37°C
additional information