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2.7.7.12: UDP-glucose-hexose-1-phosphate uridylyltransferase

This is an abbreviated version!
For detailed information about UDP-glucose-hexose-1-phosphate uridylyltransferase, go to the full flat file.

Word Map on EC 2.7.7.12

Reaction

UDP-alpha-D-glucose
+
alpha-D-galactose 1-phosphate
=
alpha-D-glucose 1-phosphate
+
UDP-alpha-D-galactose

Synonyms

galactose 1-phosphate uridylyltransferase, galactose-1-phosphate uridyl transferase, galactose-1-phosphate uridyltransferase, galactose-1-phosphate uridylyltransferase, galactose-1-phosphate:uridyltransferase, GALT, GALT enzyme, GalT1, GalT2, hexose 1-phosphate uridyltransferase, hexose 1-phosphate uridylyltransferase, hexose-1-phosphate uridylyltransferase, UDP-Glc-hexose-1-P uridylyltransferase, UDP-glucose-hexose-1-P uridylyltransferase, UDPGlc:Gal-1-P uridylyltransferase, UDPglucose-hexose-1-phosphate uridylyltransferase, UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase, uridine diphosphoglucose:alpha-D-galactose-1-phosphate uridilyltransferase, uridyl transferase, uridyltransferase, uridylylgalactose-1-P uridylyltransferase, uridylyltransferase, hexose 1-phosphate

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.12 UDP-glucose-hexose-1-phosphate uridylyltransferase

Specific Activity

Specific Activity on EC 2.7.7.12 - UDP-glucose-hexose-1-phosphate uridylyltransferase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0006
-
partially purified recombinant mutant Q188R
0.00066
-
purified recombinant mutant Q168R
0.00093
0.008
-
HepG2 cells grown on glucose medium
0.012
-
HepG2 cells grown on galactose medium
0.018
purified recombinant mutant H164N
0.023
0.03
-
partially purified recombinant mutant Q188N
0.058
-
purified enzyme
0.06
purified recombinant mutant C52S
0.08
-
partially purified recombinant wild-type enzyme
0.1
-
recombinant mutant Q168G and Q168H, cell extract
0.19
-
recombinant mutant Q168N, cell extract
0.235
substrate N-acetyl-alpha-D-glucose 1-phosphate, pH 7.0, 37°C
0.261
substrate alpha-D-galactose 1-phosphate, pH 7.0, 37°C
0.3
purified recombinant mutant C55S
0.334
substrate N-acetyl-alpha-D-galactose 1-phosphate, pH 7.0, 37°C
1.6
-
purified recombinant mutant P185E
1080
-
purified recombinant bifunctional chimeric fusion protein
12
-
purified recombinant enzyme mutant S135L
12.4
-
purified enzyme
122
-
purified recombinant wild-type enzyme
137
-
purified enzyme
15.1
-
purified enzyme
16.8
-
purified enzyme
170 - 190
-
purified recombinant enzyme
2.6
-
purified recombinant mutant P185Q
2.9
purified recombinant mutant H115N
209
-
purified enzyme
238
-
purified enzyme
25.7
-
purified enzyme
3.4
-
purified recombinant mutant Q168N
40
-
purified enzyme
44
-
erythrocytes
5.53
-
purified enzyme
54.1
-
purified enzyme
56.1
-
purified enzyme
6.14
-
purified recombinant mutant P185S
6.9
-
purified recombinant mutant P185G
88.5
purified recombinant mutant E182A
9.3
-
purified recombinant mutant P185A
92.2
-
purified enzyme from placenta
additional information