2.7.6.5: GTP diphosphokinase

This is an abbreviated version!
For detailed information about GTP diphosphokinase, go to the full flat file.

Word Map on EC 2.7.6.5

2.7.6.5

pppgpp

rela

rsh

tetraphosphate

a-site

actinorhodine

mupirocin

ribosome-dependent

sass

3'-diphosphate

rela-spot

thiostrepton

pyrophosphorylate

rela-dependent

drug development

Reaction

guanosine 3'-diphosphate 5'-triphosphate

Synonyms

(p)ppGpp synthase, (p)ppGpp synthetase, (p)ppGpp synthetase I, (p)ppGpp synthetase II, (p)ppGpp synthetase/hydrolase, alarmone synthetase, ATP-GTP 3'-diphosphotransferase, ATP:GTP 3'-pyrophosphotransferase, ATP:GTP pyrophosphoryl transferase, GPSI, GPSII, GTP pyrophosphokinase, guanosine 3',5'-polyphosphate synthase, guanosine 3',5'-polyphosphate synthetase, guanosine 5',3'-polyphosphate synthetase, guanosine pentaphosphate synthetase, ppGpp synthase I, Rel, Rel/Spo protein, RelA, RelMtb, RelMtb protein, RelP, RelSeq, RSH3, SAS 1, SAS 2, SAS1, SF, small alarmone synthase 1, small alarmone synthase 2, small alarmone synthetase 1, stringent factor, YjbM, YwaC

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.6 Diphosphotransferases

2.7.6.5 GTP diphosphokinase

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Results	in table
17	Activating Compound
15662	AA Sequence
1	Application
1	CAS Registry Number
12	Cloned(Commentary)
4	Cofactor
5	Crystallization (Commentary)
4	Expression
21	General Information
1	General Stability
2	IC50 Value
14	Inhibitors
26	KM Value [mM]
4	Localization
14	Metals/Ions
12	Molecular Weight [Da]
29	Natural Substrates/ Products (Substrates)
98	Organism
5	Pathway
70	PDB ID
2	pH Optimum
1	pI Value
28	Protein Variants
10	Purification (Commentary)
4	Reaction
5	Reaction Type
42	Reference
1	Renatured (Commentary)
14	Source Tissue
6	Specific Activity [micromol/min/mg]
65	Substrates and Products (Substrate)
5	Subunits
76	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
11	Turnover Number [1/s]

Purification

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Purification on EC 2.7.6.5 - GTP diphosphokinase

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4 entries

affinity-chromatography and precipitation

Escherichia coli

661712

HiTrap column chromatography

Escherichia coli

721638

Ni-NTA column chromatography, and gel filtration

Mycolicibacterium smegmatis

722545

recombinant His-tagged enzyme from Escherichia coli strain BL21 (DE3) pLysS by nickel affinity chromatography and gel filtration

Francisella tularensis subsp. tularensis

Q5NEV0

737883

recombinant His-tagged enzyme from Escherichia coli strain BL21(DE3) by nickel affinity chromatography and gel filtration

Bacillus subtilis

O31611

739546

the catalytic fragment RelSeq 1-385

Streptococcus dysgalactiae

661439