2.7.6.5: GTP diphosphokinase

This is an abbreviated version!
For detailed information about GTP diphosphokinase, go to the full flat file.

Word Map on EC 2.7.6.5

2.7.6.5

pppgpp

rela

rsh

tetraphosphate

a-site

actinorhodine

mupirocin

ribosome-dependent

sass

3'-diphosphate

rela-spot

thiostrepton

pyrophosphorylate

rela-dependent

drug development

Reaction

guanosine 3'-diphosphate 5'-triphosphate

Synonyms

(p)ppGpp synthase, (p)ppGpp synthetase, (p)ppGpp synthetase I, (p)ppGpp synthetase II, (p)ppGpp synthetase/hydrolase, alarmone synthetase, ATP-GTP 3'-diphosphotransferase, ATP:GTP 3'-pyrophosphotransferase, ATP:GTP pyrophosphoryl transferase, GPSI, GPSII, GTP pyrophosphokinase, guanosine 3',5'-polyphosphate synthase, guanosine 3',5'-polyphosphate synthetase, guanosine 5',3'-polyphosphate synthetase, guanosine pentaphosphate synthetase, ppGpp synthase I, Rel, Rel/Spo protein, RelA, RelMtb, RelMtb protein, RelP, RelSeq, RSH3, SAS 1, SAS 2, SAS1, SF, small alarmone synthase 1, small alarmone synthase 2, small alarmone synthetase 1, stringent factor, YjbM, YwaC

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.6 Diphosphotransferases

2.7.6.5 GTP diphosphokinase

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Results	in table
17	Activating Compound
15662	AA Sequence
1	Application
1	CAS Registry Number
12	Cloned(Commentary)
4	Cofactor
5	Crystallization (Commentary)
4	Expression
21	General Information
1	General Stability
2	IC50 Value
14	Inhibitors
26	KM Value [mM]
4	Localization
14	Metals/Ions
12	Molecular Weight [Da]
29	Natural Substrates/ Products (Substrates)
98	Organism
5	Pathway
70	PDB ID
2	pH Optimum
1	pI Value
28	Protein Variants
10	Purification (Commentary)
4	Reaction
5	Reaction Type
42	Reference
1	Renatured (Commentary)
14	Source Tissue
6	Specific Activity [micromol/min/mg]
65	Substrates and Products (Substrate)
5	Subunits
76	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
11	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 2.7.6.5 - GTP diphosphokinase

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adenosine 5'-(beta,gamma-Imino)triphosphate

Brevibacillus brevis

642771

alpha,beta-methylene-ATP

Streptococcus dysgalactiae

dGDP

dGTP

guanosine 3'-diphosphate 5'-diphosphate

Staphylococcus aureus

W8TMV6

761487

guanosine 3'-diphosphate 5'-triphosphate

Staphylococcus aureus

product inhibition

Mg2+

micrococcin

ribosome-dependent activity

tetracycline

Thiostrepton

viomycin

ribosome-dependent activity

661712