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2.7.6.1: ribose-phosphate diphosphokinase

This is an abbreviated version!
For detailed information about ribose-phosphate diphosphokinase, go to the full flat file.

Word Map on EC 2.7.6.1

Reaction

ATP
+
D-ribose 5-phosphate
=
AMP
+
5-phospho-alpha-D-ribose 1-diphosphate

Synonyms

5-phospho-alpha D-ribosyl 1-diphosphate synthase, 5-phosphoribose pyrophosphorylase, 5-phosphoribosyl-1-alpha-diphosphate synthase, 5-phosphoribosyl-1-pyrophosphate synthetase, 5-phosphoribosyl-alpha-1-pyrophosphate synthetase, AN6711.2, ATP: D-ribose-5-phosphate pyrophosphotransferase, ATP:D-ribose-5-phosphate pyrophosphotransferase, bsPRS, Pcal_1127, phosphoribosyl diphosphate synthase, phosphoribosyl pyrophosphate synthase 1 (PRS-1), phosphoribosyl pyrophosphate synthase enzyme, phosphoribosyl pyrophosphate synthetase, phosphoribosyl-1-pyrophosphate synthetase, phosphoribosyl-diphosphate synthetase, phosphoribosylpyrophosphate synthase, phosphoribosylpyrophosphate synthetase, phosphoribosylpyrophosphate synthetase 1, phosphoribosylpyrophosphate synthetase subunit 1, PP-ribose P synthetase, PPRibP synthetase, PRibPP synthase, PRPP synthase, PRPP synthetase, PRPPase, PRPPS, PRPPS1, PRPPS2, PRPS1, Prps1a, Prps1b, PRS, PRS-I, PRS1, Prs4, PrsA, PrsB, PrsC, pyrophosphokinase, ribose phosphate, pyrophosphoribosylphosphate synthetase, ribophosphate pyrophosphokinase, ribose-5-phosphate pyrophosphokinase, ribose-phosphate pyrophosphokinase, ribose-phosphate pyrophosphokinase 1, RPPK, SSO1045, TT_C1184, TT_C1274

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.6 Diphosphotransferases
                2.7.6.1 ribose-phosphate diphosphokinase

KI Value

KI Value on EC 2.7.6.1 - ribose-phosphate diphosphokinase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.41 - 0.55
2',3'-dideoxy-2',3'-didehydro-adenosine-5'-monophosphate
0.03 - 2.2
5-phospho-alpha-D-ribose 1-diphosphate
1.4
9-(2-phosphonylmethoxyethoxy)adenine
-
pH 8.0, 37ÂșC
0.37 - 1.9
9-(2-phosphonylmethoxyethyl)adenine
0.01 - 1.22
ADP
0.85
alpha,beta-methylene ATP
pH and temperature not specified in the publication
0.03
alpha,beta-methyleneATP
-
pH and temperature conditions not mentioned
0.01 - 5.6
AMP
0.167 - 1.089
ATP
0.032 - 0.11
Ca2+
0.211 - 1.18
D-ribose 5-phosphate
10
DL-1,4-Anhydroribitol 5-phosphate
-
pH and temperature conditions not mentioned
0.02
Mn2+
-
pH 7.5, 37ÂșC
0.15 - 0.75
TDP
additional information
additional information
-
-
-