2.7.4.7: phosphooxymethylpyrimidine kinase

This is an abbreviated version!
For detailed information about phosphooxymethylpyrimidine kinase, go to the full flat file.

Word Map on EC 2.7.4.7

2.7.4.7

thiamin

auxotrophic

hydroxyethylthiazole

pyrophosphate

2.7.1.35

Reaction

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

Synonyms

2-methyl-4-amino-5-hydroxymethylpyrimidine monophosphate kinase, CCC13826_0338, CcThiD2, HMP-P kinase, HMP/HMP phosphate kinase, HMPPK, HVO_2666, hydroxymethylpyrimidine phosphate kinase, hydroxymethylpyrimidine phosphokinase, kinase, phosphomethylpyrimidine (phosphorylating), More, phosphomethylpyrimidine kinase, StHMPPK, Suden_2055, TdThiD2, Thi20, Thi20p, Thi20p protein, Thi21p protein, thiamine phosphate synthase, ThiD, ThiD2, ThiD2 domain-containing protein, TTHA0680, TtHMPPK

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.4 Phosphotransferases with a phosphate group as acceptor

2.7.4.7 phosphooxymethylpyrimidine kinase

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Results	in table
13889	AA Sequence
1	CAS Registry Number
9	Cloned(Commentary)
2	Crystallization (Commentary)
44	General Information
3	IC50 Value
4	Inhibitors
2	kcat/KM [mM/s]
7	KM Value [mM]
1	Localization
8	Metals/Ions
2	Molecular Weight [Da]
27	Natural Substrates/ Products (Substrates)
31	Organism
9	Pathway
14	PDB ID
8	pH Optimum
7	Protein Variants
10	Purification (Commentary)
8	Reaction
1	Reaction Type
30	Reference
3	Storage Stability
44	Substrates and Products (Substrate)
4	Subunits
65	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
4	Temperature Stability [°C]
5	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.7.4.7 - phosphooxymethylpyrimidine kinase

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ATP + (4-amino-2-methylpyrimidin-5-yl)methyl phosphate

ADP + (4-amino-2-methylpyrimidin-5-yl)methyl diphosphate

Saccharomyces cerevisiae

Q08224

661316, 686824

ATP + 2-methyl-4-amino-5-hydroxymethylpyrimidine

ADP + 2-methyl-4-amino-5-phosphomethylpyrimidine

Escherichia coli

involved in thiamine biosynthesis

641660

ATP + 2-methyl-4-amino-5-phosphomethylpyrimidine

ADP + 2-methyl-4-amino-5-diphosphomethylpyrimidine

3 entries

ATP + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

ADP + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

18 entries

ATP + 4-amino-2-methyl-phosphomethylpyrimidine

ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine

2 entries

ATP + 4-amino-5-hydroxymethyl-2-methylpyrimidine

ADP + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

Haloferax volcanii

D4GV38

the enzyme is involved in biosynthesis of thiamine

759429