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2.7.4.3: adenylate kinase

This is an abbreviated version!
For detailed information about adenylate kinase, go to the full flat file.

Word Map on EC 2.7.4.3

Reaction

ATP
+
AMP
=
2 ADP

Synonyms

5'-AMP-kinase, ABC adenylate kinase, AD-004 like protein, adenosine 5'-triphosphate:adenosine 5'-monophosphate phosphotransferase, adenylate kinase, adenylate kinase 1, adenylate kinase 2, adenylate kinase 4, adenylate kinase 5, adenylate kinase 6, adenylate kinase 9, adenylate kinase isoenzyme 1, adenylate kinase isozyme 2, adenylate kinase-2, adenylate kinase-like protein 1, adenylic kinase, adenylokinase, ADK, ADK1, ADK2, ADLP, AK1, AK2, AK4, AK5, AK5p1, AK5p2, AK6, AK7, AK8, AK9, AKE, AKlse4, AKm, AKmeso, AKp, AKpsycrho, AKthermo, ATP:AMP phosphotransferase, CFTR, CINAP, coilin interacting nuclear ATPase protein, cystic fibrosis transmembrane conductance regulator, DAK2, Dak6, kinase, adenylate (phosphorylating), kinase, myo- (phosphorylating), MeADK1, MeADK2, MJ0458, myokinase, nonstructural protein 4B, NS4B, pfSMCnbd, phosphotransferase, Rv0733, Saci_0573, SpAdK, structural maintenance of chromosome protein

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.4 Phosphotransferases with a phosphate group as acceptor
                2.7.4.3 adenylate kinase

pH Range

pH Range on EC 2.7.4.3 - adenylate kinase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
3.5 - 7
-
about half-maximal activity at pH 3.5 and about 70% of maximal activity at pH 7, ADP + ADP, 70°C
4 - 7.5
-
about half-maximal activity at pH 4 and about 70% of maximal activity at pH 7.5, AMP + ATP, 70°C
5 - 10
-
less than 20% of maximal activity at pH 5, 5.5, 6 and pH 9.5 and 10, about half-maximal activity at pH 6.9 and 8.4
5 - 7.5
-
about half-maximal activity at pH 5 and 7.5, AMP + ATP, acidic heart enzyme
5.1 - 11
-
about half-maximal activity at pH 5.1 and pH 11, muscle enzyme
5.5 - 10
-
about half-maximal activity at pH 5.5 and about 60% of maximal activity at pH 10, AMP + ATP
5.6 - 10.5
-
about half-maximal activity at pH 5.6 and about 60% of maximal activity at pH 10.5
5.8 - 6.5
Megalodesulfovibrio gigas
-
direction of ADP formation
6 - 10
6 - 11
-
about half-maximal activity at pH 6 and 11, ADP + ADP
6 - 8.5
-
about half-maximal activity at pH 6 and 8.5, ADP + ADP, acidic heart enzyme
6.5 - 8.2
-
about half-maximal activity at pH 6.5 and 8.2
6.9 - 8.4
-
about half-maximal activity at pH 6.9 and 8.4
7
more than 70% active
7.5 - 9
Megalodesulfovibrio gigas
-
direction of ATP formation
8 - 10
-
about half-maximal activity at pH 7.5
8.5
more than 70% active
8.5 - 11.5
-
about half-maximal activity at pH 8.5 and 11.5, ADP + ADP