2.7.4.3: adenylate kinase
This is an abbreviated version!
For detailed information about adenylate kinase, go to the full flat file.
Word Map on EC 2.7.4.3
-
2.7.4.3
-
phosphoenolpyruvate
-
adp
-
creatine
-
hpr
-
fructose
-
nucleoside
-
permease
-
streptococcus
-
phosphoenolpyruvate-dependent
-
mannose
-
6-phosphate
-
catabolite
-
deaminase
-
lactose
-
mannitol
-
hexokinase
-
mutans
-
glucose-6-phosphate
-
camp-dependent
-
aminoglycoside
-
autophosphorylation
-
phosphoglucomutase
-
phosphofructokinase
-
kanamycin
-
neomycin
-
6-phosphogluconate
-
phosphorelay
-
5'-nucleotidase
-
antiterminator
-
mgatp
-
2-deoxyglucose
-
intermembrane
-
transphosphorylation
-
gamma-phosphate
-
melibiose
-
salivarius
-
ganciclovir
-
phosphocreatine
-
nptii
-
diadenosine
-
diphosphohydrolase
-
gamma-32patp
-
p-loop
-
2.7.3.2
-
dikinase
-
coarse-grained
-
analysis
-
phosvitin
-
medicine
-
2,6-bisphosphate
-
mucolipidosis
-
phosphoenzyme
-
diagnostics
- 2.7.4.3
- phosphoenolpyruvate
- adp
- creatine
- hpr
- fructose
- nucleoside
-
permease
- streptococcus
-
phosphoenolpyruvate-dependent
- mannose
- 6-phosphate
-
catabolite
- deaminase
- lactose
- mannitol
- hexokinase
- mutans
- glucose-6-phosphate
-
camp-dependent
- aminoglycoside
- autophosphorylation
- phosphoglucomutase
-
phosphofructokinase
- kanamycin
- neomycin
- 6-phosphogluconate
-
phosphorelay
- 5'-nucleotidase
-
antiterminator
- mgatp
- 2-deoxyglucose
-
intermembrane
-
transphosphorylation
-
gamma-phosphate
- melibiose
- salivarius
- ganciclovir
- phosphocreatine
- nptii
-
diadenosine
-
diphosphohydrolase
-
gamma-32patp
-
p-loop
-
2.7.3.2
- dikinase
-
coarse-grained
- analysis
- phosvitin
- medicine
-
2,6-bisphosphate
- mucolipidosis
- phosphoenzyme
- diagnostics
Reaction
Synonyms
5'-AMP-kinase, ABC adenylate kinase, AD-004 like protein, adenosine 5'-triphosphate:adenosine 5'-monophosphate phosphotransferase, adenylate kinase, adenylate kinase 1, adenylate kinase 2, adenylate kinase 4, adenylate kinase 5, adenylate kinase 6, adenylate kinase 9, adenylate kinase isoenzyme 1, adenylate kinase isozyme 2, adenylate kinase-2, adenylate kinase-like protein 1, adenylic kinase, adenylokinase, ADK, ADK1, ADK2, ADLP, AK1, AK2, AK4, AK5, AK5p1, AK5p2, AK6, AK7, AK8, AK9, AKE, AKlse4, AKm, AKmeso, AKp, AKpsycrho, AKthermo, ATP:AMP phosphotransferase, CFTR, CINAP, coilin interacting nuclear ATPase protein, cystic fibrosis transmembrane conductance regulator, DAK2, Dak6, kinase, adenylate (phosphorylating), kinase, myo- (phosphorylating), MeADK1, MeADK2, MJ0458, myokinase, nonstructural protein 4B, NS4B, pfSMCnbd, phosphotransferase, Rv0733, Saci_0573, SpAdK, structural maintenance of chromosome protein
ECTree
2.7.4.3 adenylate kinaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 2.7.4.3 - adenylate kinase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
1,N6-ethenoadenosine 5'-triphosphate + AMP
? + ADP
-
not ATP + 1,N6-ethenoadenosine 5'monophosphate
-
-
ir
adenosine 5'-(3-thio)triphosphate + AMP
adenosine 5'-diphosphate + adenosine 5'-(3-thio)diphosphate
-
muscle: reaction at 97% the rate of ATP, liver mitochondria: reaction at 70% the rate of ATP
-
-
?
ADP + diphosphate
ATP + phosphate
-
at 0.1% the rate of the natural substrates
-
-
?
ATP + 7-deazaadenosine 5'-monophosphate
ADP + 7-deazaadenosine 5'-diphosphate
-
i.e. tubercidine monophosphate
-
-
?
ATP + adenine-9-beta-D-arabinofuranoside 5'-monophosphate
ADP + adenine-9-beta-D-arabinofuranoside 5'-diphosphate
-
-
-
-
?
ATP + adenosine 5'-thiophosphate
?
-
muscle: reaction at 56% the rate of AMP, liver mitochondria: reaction at 95% the rate of AMP
-
-
?
ATP + AMP-3'-diphosphate
?
-
muscle: reaction at 57% the rate of AMP, liver mitochondria: reaction at 86% the rate of AMP
-
-
?
ATP + CDP
ADP + CTP
-
-
nucleoside triphosphate synthesis by beta-phosphoryl transfer from ADP to any bound nucleoside diphosphate
-
r
ATP + shikimic acid
ADP + ?
shikimic acid is a good substrate
-
-
?
dATP + dAMP
dADP + dADP
AMP and dAMP are the preferred substrates
-
-
?
2 ADP
ATP + AMP
the enzyme plays a key role in maintaining the balance of ADP and ATP in cell
-
-
r
2 ADP
ATP + AMP
molecular simulations of substrate release and coupled conformational motions in adenylate kinase
-
-
r
2 ADP
ATP + AMP
the enzyme plays a key role in maintaining the balance of ADP and ATP in cell
-
-
r
2 ADP
ATP + AMP
molecular simulations of substrate release and coupled conformational motions in adenylate kinase
-
-
r
2 ADP
ATP + AMP
the Escherichia coli-produced recombinant enzyme preferrs forward reaction that produces ATP
-
-
r
2 ADP
ATP + AMP
the Escherichia coli-produced recombinant enzyme prefers forward reaction that produces ATP
-
-
r
2 ADP
ATP + AMP
pfSMCnbd possesses reverse adenylate kinase activity. In adenylate kinase reactions, ATP binds to its canonical binding site while AMP binds to the Q-loop glutamine and a hydration water of the Mg2+ ion. Furthermore, mutational analysis indicates that adenylate kinase reaction occurs in the engaged pfSMCnbd dimer and requires the Signature motif for phosphate transfer
-
-
?
ADP + ADP
?
-
facilitates storage and use of the high energy of the adenine nucleotides, involved in maintenance of equilibrium among adenine nucleotides and maintenance of energy charge, important to energy economy of living systems
-
-
r
ADP + ADP
?
-
facilitates storage and use of the high energy of the adenine nucleotides, involved in maintenance of equilibrium among adenine nucleotides and maintenance of energy charge, important to energy economy of living systems
-
-
r
ADP + ADP
?
-
facilitates storage and use of the high energy of the adenine nucleotides, involved in maintenance of equilibrium among adenine nucleotides and maintenance of energy charge, important to energy economy of living systems
-
-
r
ADP + ADP
?
-
facilitates transfer of high-energy phosphorylss and signal communication between mitochondria and actomyosin in cardiac muscle
-
-
?
ADP + ADP
?
-
facilitates storage and use of the high energy of the adenine nucleotides, involved in maintenance of equilibrium among adenine nucleotides and maintenance of energy charge, important to energy economy of living systems
-
-
r
ADP + ADP
?
-
facilitates storage and use of the high energy of the adenine nucleotides, involved in maintenance of equilibrium among adenine nucleotides and maintenance of energy charge, important to energy economy of living systems
-
-
r
ADP + ADP
?
-
facilitates storage and use of the high energy of the adenine nucleotides, involved in maintenance of equilibrium among adenine nucleotides and maintenance of energy charge, important to energy economy of living systems
-
-
r
ADP + ADP
?
-
facilitates storage and use of the high energy of the adenine nucleotides, involved in maintenance of equilibrium among adenine nucleotides and maintenance of energy charge, important to energy economy of living systems
-
-
r
ADP + ADP
?
-
facilitates transfer of high-energy phosphorylss and signal communication between mitochondria and actomyosin in cardiac muscle
-
-
?
ADP + ADP
?
-
facilitates storage and use of the high energy of the adenine nucleotides, involved in maintenance of equilibrium among adenine nucleotides and maintenance of energy charge, important to energy economy of living systems
-
-
r
ADP + ADP
?
-
facilitates storage and use of the high energy of the adenine nucleotides, involved in maintenance of equilibrium among adenine nucleotides and maintenance of energy charge, important to energy economy of living systems
-
-
r
ADP + ADP
?
-
facilitates storage and use of the high energy of the adenine nucleotides, involved in maintenance of equilibrium among adenine nucleotides and maintenance of energy charge, important to energy economy of living systems
-
-
r
ADP + ADP
?
-
facilitates storage and use of the high energy of the adenine nucleotides, involved in maintenance of equilibrium among adenine nucleotides and maintenance of energy charge, important to energy economy of living systems
-
-
r
ADP + ADP
?
-
facilitates storage and use of the high energy of the adenine nucleotides, involved in maintenance of equilibrium among adenine nucleotides and maintenance of energy charge, important to energy economy of living systems
-
-
r
ADP + ADP
?
-
facilitates storage and use of the high energy of the adenine nucleotides, involved in maintenance of equilibrium among adenine nucleotides and maintenance of energy charge, important to energy economy of living systems
-
-
r
ADP + ADP
?
-
facilitates storage and use of the high energy of the adenine nucleotides, involved in maintenance of equilibrium among adenine nucleotides and maintenance of energy charge, important to energy economy of living systems
-
-
r
ADP + ADP
?
-
provides unique buffering role against rapid concentration changes of any component of the adenylate pool
-
-
?
ADP + ADP
ATP + AMP
-
no substrates: adenosine 5'-(2-thio)diphosphate, adenosine diphosphate 3'-diphosphate
-
-
?
ADP + ADP
ATP + AMP
-
-
-
-
r
ADP + TDP
AMP + TTP
-
Escherichia coli adenylate kinase is able to synthesize TTP, but the activity is too low to explain the high rate of TTP accumulation uring amino acid starvation of cells
-
-
?
ADP + TDP
AMP + TTP
-
rate of TTP synthesis is more than 1000000fold lower than ATP synthesis
-
-
?
AMP + H2O
ADP + phosphate
GMP can not be substituted for the AMP substrate
-
-
r
AMP + H2O
ADP + phosphate
GMP can not be substituted for the AMP substrate
-
-
r
ATP + AMP
2 ADP
AMP and dAMP are the preferred substrates, ATP is the best phosphate donor
-
-
?
ATP + AMP
2 ADP
-
substrate ligand-binding modeling, detailed overview
-
-
r
ATP + AMP
2 ADP
the enzyme is involved in regulating concentration of ATP in cells
-
-
?
ATP + AMP
2 ADP
the enzyme plays a key role in maintaining the balance of ADP and ATP in cell
-
-
r
ATP + AMP
2 ADP
electrostatic interactions determine entrance and release order of substrates in the catalytic cycle of adenylate kinase
-
-
?
ATP + AMP
2 ADP
molecular simulations of substrate release and coupled conformational motions in adenylate kinase
-
-
r
ATP + AMP
2 ADP
the enzyme has 3 domains, the LID, NMP, and CORE domains, that undergo large conformational rearrangements during catalytic cycle of adenylate kinase. The pathway from open to closed forms is explored using coarse-grained molecular dynamics trajectories of adenosine kinase calculated by GROMACS using a SMOG model and classify the conformations within the resultant trajectories by K-means clustering
-
-
?
ATP + AMP
2 ADP
the results of the study are more consistent with proposals that adenylate kinase belongs to a group of enzymes in which substrate binding is the predominant mechanism for driving the protein into a catalytically active state, rather than the population-shift model
-
-
?
ATP + AMP
2 ADP
the results of the study are more consistent with proposals that adenylate kinase belongs to a group of enzymes in which substrate binding is the predominant mechanism for driving the protein into a catalytically active state, rather than the population-shift model
-
-
?
ATP + AMP
2 ADP
the enzyme plays a key role in maintaining the balance of ADP and ATP in cell
-
-
r
ATP + AMP
2 ADP
molecular simulations of substrate release and coupled conformational motions in adenylate kinase
-
-
r
ATP + AMP
2 ADP
the enzyme has 3 domains, the LID, NMP, and CORE domains, that undergo large conformational rearrangements during catalytic cycle of adenylate kinase. The pathway from open to closed forms is explored using coarse-grained molecular dynamics trajectories of adenosine kinase calculated by GROMACS using a SMOG model and classify the conformations within the resultant trajectories by K-means clustering
-
-
?
ATP + AMP
2 ADP
the enzyme is involved in regulating concentration of ATP in cells
-
-
?
ATP + AMP
2 ADP
electrostatic interactions determine entrance and release order of substrates in the catalytic cycle of adenylate kinase
-
-
?
ATP + AMP
2 ADP
-
substrate ligand-binding modeling, detailed overview
-
-
r
ATP + AMP
2 ADP
tracking of the catalytic cycle of adenylate kinase by ultraviolet photodissociation mass spectrometry
-
-
?
ATP + AMP
2 ADP
XP_019937160.1
the molar ratio for ATP:ADP:AMP in the equilibrium state of the reaction is about 1:1:1
-
-
r
ATP + AMP
2 ADP
-
substrate ligand-binding modeling, detailed overview
-
-
r
ATP + AMP
ADP + ADP
-
ATP is the preferred phosphate donor and AMP is the best phosphate acceptor
-
-
?
ATP + AMP
ADP + ADP
-
specificity for AMP-site is much more rigorous than for ATP-site
-
r
ATP + AMP
ADP + ADP
-
specificity for AMP-site is much more rigorous than for ATP-site
-
r
ATP + AMP
ADP + ADP
-
specificity for AMP-site is much more rigorous than for ATP-site
-
r
ATP + AMP
ADP + ADP
-
specificity for AMP-site is much more rigorous than for ATP-site
-
r
ATP + AMP
ADP + ADP
-
specificity for AMP-site is much more rigorous than for ATP-site
-
r
ATP + AMP
ADP + ADP
-
no substrates are O1-AMP, epsilon-AMP, 8-bromo-AMP, 2',3'-dialdehyde-AMP
-
r
ATP + AMP
ADP + ADP
-
in addition to the hydrolysis of NTP and NDP substrates, adenylate kinase activity is detected in purified preparations of nonstructural protein 4B with the reverse reaction ADP + ADP -> ATP + AMP, yielding a larger kcat compared to that of the forward reaction ATP + AMP -> ADP + ADP
-
-
?
ATP + AMP
ADP + ADP
-
specificity for AMP-site is much more rigorous than for ATP-site
-
r
ATP + AMP
ADP + ADP
-
specificity for AMP-site is much more rigorous than for ATP-site
-
r
ATP + AMP
ADP + ADP
-
no substrates are adenosine triphosphate 3'-diphosphate, adenosine-5'-(3-thio)triphosphate/adenosine 5'-thiophosphate
-
r
ATP + AMP
ADP + ADP
-
no substrates of the reverse reaction: adenosine 5'-(2-thio)diphosphate, adenosine diphosphate 3'-diphosphate
-
r
ATP + AMP
ADP + ADP
adenylate kinase 4 shows slightly lower efficiency for the phosphorylation of AMP with ATP compared to the phosphorylation of AMP with GTP
-
-
?
ATP + AMP
ADP + ADP
adenylate kinase 5 domain AK5p1, at the assay conditions used, and at lower concentrations of substrate, AK5p1 shows generally a higher affinity for AMP compared to dAMP
-
-
?
ATP + AMP
ADP + ADP
-
specificity for AMP-site is much more rigorous than for ATP-site
-
r
ATP + AMP
ADP + ADP
-
no substrate of the reverse reaction: UDP
-
r
ATP + AMP
ADP + ADP
-
no substrates of the reverse reaction: adenosine tetraphosphate
-
r
ATP + AMP
ADP + ADP
-
no substrates of the reverse reaction: IDP, GDP
-
r
ATP + AMP
ADP + ADP
-
substrates in decreasing order of activity, in the presence of Mn2+: ATP, 2'-dATP, CTP, GTP, UTP, ITP
-
r
ATP + AMP
ADP + ADP
-
specificity for AMP-site is much more rigorous than for ATP-site
-
r
ATP + AMP
ADP + ADP
-
the adenylate kinase-catalyzed reaction requires a nucleotide complexed with Mg2+ as one substrate and a free nucleotide as the second substrate
-
-
r
ATP + AMP
ADP + ADP
-
specificity for AMP-site is much more rigorous than for ATP-site
-
r
ATP + AMP
ADP + ADP
Q14EL6
the substrate pair ATP/AMP results in maximal activity
-
-
?
ATP + AMP
ADP + ADP
-
no substrates are 3',5'-cAMP, dAMP, 2'-AMP, 3'-AMP
-
r
ATP + AMP
ADP + ADP
-
specificity for AMP-site is much more rigorous than for ATP-site
-
r
ATP + AMP
ADP + ADP
other NMP substrates are very poor acceptors
-
-
?
ATP + AMP
ADP + ADP
other NMP substrates are very poor acceptors
-
-
?
ATP + AMP
ADP + ADP
-
specificity for AMP-site is much more rigorous than for ATP-site
-
r
ATP + AMP
ADP + ADP
-
substrates in decreasing order of activity, in the presence of Mg2+: ATP, dATP, GTP, ITP
-
r
ATP + AMP
ADP + ADP
-
no substrates are adenosine, 2',3'-AMP or 3',5'-AMP
-
r
ATP + AMP
ADP + ADP
-
no substrates of the reverse reaction: IDP, GDP
-
r
ATP + AMP
ADP + ADP
-
no substrates are GTP/GMP, TTP/TMP
-
r
ATP + AMP
ADP + ADP
-
specificity for AMP-site is much more rigorous than for ATP-site
-
r
ATP + AMP
ADP + ADP
-
specificity for AMP-site is much more rigorous than for ATP-site
-
r
ATP + AMP
ADP + ADP
-
specificity for AMP-site is much more rigorous than for ATP-site
-
r
ATP + CMP
ADP + CDP
adenylate kinase 5 domain AK5p1, the relative efficiency of CMP is about 15% compared to AMP
-
-
?
ATP + CMP
ADP + CDP
phosphorylation of CMP is also detected but to a lesser extend
-
-
?
ATP + dCMP
ADP + dCDP
dCMP is a poor substrate, but preferred over IMP, UMP
-
-
?
ATP + dCMP
ADP + dCDP
adenylate kinase 5 domain AK5p1, the relative efficiency of dCMP is about 15% compared to AMP
-
-
?
dATP + AMP
dADP + ADP
AMP and dAMP are the preferred substrates, dATP is a good phosphate donor
-
-
?
GTP + AMP
GDP + ADP
isozyme adenylate kinase 4 shows its highest efficiency when phosphorylating AMP with GTP, when GTP is used as phosphate donor only AMP is clearly phosphorylated and the phosphorylation efficiency for dAMP, CMP and dCMP is very low
-
-
?
additional information
?
-
interaction between mitochondrial adenylate kinase and nucleoside diphosphate kinase. Adenylate kinase stimulates nucleoside diphosphate kinase activity, whereas nucleoside diphosphate kinase inhibits adenylate kinase activity. the net effect may be unchanged ADP production albeit with different rates of substrate consumption
-
-
?
additional information
?
-
-
the enzyme has broader specificity for NMPs than mammalian enzymes
-
-
?
additional information
?
-
-
adenylate kinase participates in the regulation of ADP-dependent endocytosis of high-density lipoprotein by consuming the ADP generated by the ecto-F1-ATPase
-
-
?
additional information
?
-
nucleotide-binding domains 1 and 2 cannot hydrolyze ATP
-
-
?
additional information
?
-
-
nucleotide-binding domains 1 and 2 cannot hydrolyze ATP
-
-
?
additional information
?
-
-
adenylate kinase activity of the Mre11/Rad50 complex, which is part of a DNA repair complex, promotes DNA-DNA associations
-
-
?
additional information
?
-
adenylate kinase 4 catalyzes the phosphorylation of AMP, dAMP,CMPand dCMP with ATP or GTP as phosphate donors and also phosphorylates AMP with UTP as phosphate donor
-
-
?
additional information
?
-
AK5p1 phosphorylates AMP, CMP, dAMP and dCMP with ATP or GTP as phosphate donors, AK5p2 phosphorylates AMP, CMP and dAMP when ATP is used as phosphate donor and AMP, CMP and dCMP with GTP as phosphate donor, AK5p2 cannot phosphorylate dAMP in the presence of GTP
-
-
?
additional information
?
-
-
AK5p1 phosphorylates AMP, CMP, dAMP and dCMP with ATP or GTP as phosphate donors, AK5p2 phosphorylates AMP, CMP and dAMP when ATP is used as phosphate donor and AMP, CMP and dCMP with GTP as phosphate donor, AK5p2 cannot phosphorylate dAMP in the presence of GTP
-
-
?
additional information
?
-
CINAP has previously been designated as an adenylate kinase AK6, but is very atypical as it exhibits unusually broad substrate specificity, structural features characteristic of ATPase/GTPase proteins (Walker motifs A and B) and also intrinsic ATPase activity
-
-
?
additional information
?
-
-
CINAP has previously been designated as an adenylate kinase AK6, but is very atypical as it exhibits unusually broad substrate specificity, structural features characteristic of ATPase/GTPase proteins (Walker motifs A and B) and also intrinsic ATPase activity
-
-
?
additional information
?
-
-
the enzyme catalyzes the phosphorylation of AMP (highest affinity), dAMP, CMP and dCMP with ATP as phosphate donor, while only AMP and CMP are phosphorylated when GTP is the phosphate donor. With ATP or GTP as phosphate donor it was possible to detect the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and TTP as enzymatic products from the corresponding diphosphate substrates
-
-
?
additional information
?
-
-
the cystic fibrosis transmembrane conductance regulator (CFTR) has adenylate kinase activity as an ABC adenylate kinase. ATP enables CFTR photolabeling by 8-N3-AMP, and AMP increases 8-N3-ATP photolabeling at ATP-binding site 2. AMP interacts with CFTR in an ATP-dependent manner and alters ATP interaction with the adenylate kinase active center ATP-binding site. Two other ABC proteins, Rad50 and a structural maintenance of chromosome protein, also have adenylate kinase activity. All three ABC adenylate kinases bind and hydrolyze ATP in the absence of other nucleotides
-
-
?
additional information
?
-
nucleotide-binding domain 1 cannot hydrolyze ATP
-
-
?
additional information
?
-
-
nucleotide-binding domain 1 cannot hydrolyze ATP
-
-
?
additional information
?
-
-
adenylte kinase-catalysed ADP production in the vicinity of K/ATP channels is involved in channel regulation
-
-
?
additional information
?
-
-
secretion of adenylate kinase 1 is required for extracellular ATP synthesis in myotubes
-
-
?
additional information
?
-
-
adenylate kinase is involved in the control of the rate of glycolysis
-
-
?
additional information
?
-
Q7Z0H0
monophosphates: IMP, GMP, CMP, UMP: activity below 1%
-
-
?
additional information
?
-
-
monophosphates: IMP, GMP, CMP, UMP: activity below 1%
-
-
?
additional information
?
-
Q14EL6
when replacing AMP by GMP, UMP or IMP the measured activity is less than 1%
-
-
?
additional information
?
-
-
when replacing AMP by GMP, UMP or IMP the measured activity is less than 1%
-
-
?
additional information
?
-
-
Rad50 adenylate kinase activity is required for DNA tethering
-
-
?
additional information
?
-
-
Rad50 adenylate kinase activity is required for DNA tethering
-
-
?
additional information
?
-
-
at the measured in vivo concentrations of ADP of 0.114 mM, at pH 7.6, the axonemal adenylate kinase could contribute31%, and creatine kinase 69%, of the total non-mitochondrial ATP synthesis associated with the demembranated axoneme. The three catalytic domains of adenylate kinase are considerably divergent from each other
-
-
?
additional information
?
-
at the measured in vivo concentrations of ADP of 0.114 mM, at pH 7.6, the axonemal adenylate kinase could contribute31%, and creatine kinase 69%, of the total non-mitochondrial ATP synthesis associated with the demembranated axoneme. The three catalytic domains of adenylate kinase are considerably divergent from each other
-
-
?
additional information
?
-
-
ATP + IMP 0.1% activity, ATP + GMP 0.3% activity
-
-
?
additional information
?
-
-
adenylate kinase activity Is required for Mre11/Rad50-mediated DNA tethering
-
-
?
