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2.7.4.3: adenylate kinase

This is an abbreviated version!
For detailed information about adenylate kinase, go to the full flat file.

Word Map on EC 2.7.4.3

Reaction

ATP
+
AMP
=
2 ADP

Synonyms

5'-AMP-kinase, ABC adenylate kinase, AD-004 like protein, adenosine 5'-triphosphate:adenosine 5'-monophosphate phosphotransferase, adenylate kinase, adenylate kinase 1, adenylate kinase 2, adenylate kinase 4, adenylate kinase 5, adenylate kinase 6, adenylate kinase 9, adenylate kinase isoenzyme 1, adenylate kinase isozyme 2, adenylate kinase-2, adenylate kinase-like protein 1, adenylic kinase, adenylokinase, ADK, ADK1, ADK2, ADLP, AK1, AK2, AK4, AK5, AK5p1, AK5p2, AK6, AK7, AK8, AK9, AKE, AKlse4, AKm, AKmeso, AKp, AKpsycrho, AKthermo, ATP:AMP phosphotransferase, CFTR, CINAP, coilin interacting nuclear ATPase protein, cystic fibrosis transmembrane conductance regulator, DAK2, Dak6, kinase, adenylate (phosphorylating), kinase, myo- (phosphorylating), MeADK1, MeADK2, MJ0458, myokinase, nonstructural protein 4B, NS4B, pfSMCnbd, phosphotransferase, Rv0733, Saci_0573, SpAdK, structural maintenance of chromosome protein

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.4 Phosphotransferases with a phosphate group as acceptor
                2.7.4.3 adenylate kinase

Source Tissue

Source Tissue on EC 2.7.4.3 - adenylate kinase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
vascular endothelial cells
Manually annotated by BRENDA team
-
in primary culture
Manually annotated by BRENDA team
-
adenylate kinase 2 is specifically expressed in the stria vascularis region of the inner ear
Manually annotated by BRENDA team
-
-
Manually annotated by BRENDA team
-
high expression level
Manually annotated by BRENDA team
-
expression level of adenylate kinase 1 and ATP synthase beta is strongly increased during myogenesis
Manually annotated by BRENDA team
-
cytosolic isoforms AK1 and AK5 are expressed in human islets and INS-1 cells. Elevated concentrations of glucose inhibit AK1 expression
Manually annotated by BRENDA team
-
moderate expression
Manually annotated by BRENDA team
-
high expression level
Manually annotated by BRENDA team
-
neonatal rats
Manually annotated by BRENDA team
-
sperm flagellum. 31% of the nonmitochondrial ATP regeneration are due to the 130000 Dalton adenylate kinase isozyme and 69% due to the flagellar creatine kinase
Manually annotated by BRENDA team
-
high expression level
Manually annotated by BRENDA team
-
high expression level
Manually annotated by BRENDA team
-
moderate expression
Manually annotated by BRENDA team
additional information