2.7.4.3: adenylate kinase

This is an abbreviated version!
For detailed information about adenylate kinase, go to the full flat file.

Reaction

Synonyms

5'-AMP-kinase, ABC adenylate kinase, AD-004 like protein, adenosine 5'-triphosphate:adenosine 5'-monophosphate phosphotransferase, adenylate kinase, adenylate kinase 1, adenylate kinase 2, adenylate kinase 4, adenylate kinase 5, adenylate kinase 6, adenylate kinase 9, adenylate kinase isoenzyme 1, adenylate kinase isozyme 2, adenylate kinase-2, adenylate kinase-like protein 1, adenylic kinase, adenylokinase, ADK, ADK1, ADK2, ADLP, AK1, AK2, AK4, AK5, AK5p1, AK5p2, AK6, AK7, AK8, AK9, AKE, AKlse4, AKm, AKmeso, AKp, AKpsycrho, AKthermo, ATP:AMP phosphotransferase, CFTR, CINAP, coilin interacting nuclear ATPase protein, cystic fibrosis transmembrane conductance regulator, DAK2, Dak6, kinase, adenylate (phosphorylating), kinase, myo- (phosphorylating), MeADK1, MeADK2, MJ0458, myokinase, nonstructural protein 4B, NS4B, pfSMCnbd, phosphotransferase, Rv0733, Saci_0573, SpAdK, structural maintenance of chromosome protein

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.4 Phosphotransferases with a phosphate group as acceptor

                2.7.4.3 adenylate kinase

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Results	in table
33	Activating Compound
59664	AA Sequence
20	Application
1	CAS Registry Number
72	Cloned(Commentary)
1	Cofactor
54	Crystallization (Commentary)
1147	Disease/ Diagnostics
4	Expression
46	General Information
41	General Stability
3	IC50 Value
201	Inhibitors
6	kcat/KM [mM/s]
17	Ki Value [mM]
220	KM Value [mM]
132	Localization
304	Metals/Ions
144	Molecular Weight [Da]
50	Natural Substrates/ Products (Substrates)
432	Organism
7	Pathway
264	PDB ID
40	pH Optimum
19	pH Range
29	pH Stability
27	pI Value
4	Posttranslational Modification
76	Protein Variants
100	Purification (Commentary)
34	Reaction
1	Reaction Type
279	Reference
5	Renatured (Commentary)
211	Source Tissue
84	Specific Activity [micromol/min/mg]
26	Storage Stability
494	Substrates and Products (Substrate)
102	Subunits
114	Synonyms
1	Systematic Name
49	Temperature Optimum [°C]
7	Temperature Range [°C]
93	Temperature Stability [°C]
47	Turnover Number [1/s]

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RENATURED/Commentary

ORGANISM

UNIPROT

LITERATURE

aldolase reverse inhibition by ascorbate

Oryctolagus cuniculus

-

675108

reactivation of enzyme inhibited by P1,P5-di(adenosine-5’)-pentaphosphate with 1 mM ADP if concentration of inhibitior is below 0.001 mM

Strongylocentrotus purpuratus

A2T1M5

674861

refolding of urea-denatured adenylate kinase by equilibrium dialysis against 50 mM Tris/HCl pH 8.0, containing either MgSO4, KCl or 10 mM dithiothreitol

Leishmania donovani

Q9Y0E7

661631

refolding of urea-denatured adenylate kinase, kinetics, fluorescence of 8-anilino-1-naphthalensulfonate

Oryctolagus cuniculus

-

642611

renatured upon cooling, maximum reversibility between pH 9.0 and 11.0

Megalodesulfovibrio gigas

-

661349