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2.7.4.22: UMP kinase

This is an abbreviated version!
For detailed information about UMP kinase, go to the full flat file.

Reaction

ATP
+
UMP
=
ADP
 +
UDP

Synonyms

ATP:UMP phosphotransferase, HP0777 protein, More, pyrH, Rv2883c, SsUMPK, UMP kinase, UMP-kinase, UMPK, UMPKs, uridine monophosphate kinase, uridylate kinase, XC1936

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.4 Phosphotransferases with a phosphate group as acceptor
                2.7.4.22 UMP kinase

Molecular Weight

Molecular Weight on EC 2.7.4.22 - UMP kinase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
140000
145300
wild-type, hexamer, sedimentation velocity at pH 9.0
146400
mutant D159N, hexamer, sedimentation velocity at pH 9.0
147400
mutant D159N, hexamer, sedimentation velocity at pH 7.4
150000
154000
gel filtration
156000
sedimentation equilibrium
157000
wild-type, hexamer, sedimentation velocity at pH 6.0
173200
sedimentation equilibrium ultracentrifugation
189000
major form, representing two-thirds of the protein population, gel filtration
25000
6 * 25000, SDS-PAGE
25800
26000
x * 26000, SDS-PAGE
26080
26300
mass spectroscopy, N-terminal sequencing
27500
x * 27500, His6-tagged enzyme, SDS-PAGE
28120
His-tagged protein, monomer, mass spectroscopy
28250
His-tagged protein, monomer, calculated from amino acid sequence
297400
wild-type, oligomer, sedimentation velocity at pH 9.0
32100
mutant D159N, monomer, sedimentation velocity at pH 9.0
32800
wild-type, monomer, sedimentation velocity at pH 9.0
35300
mutant D159N, monomer, sedimentation velocity at pH 7.4
482900
wild-type, oligomer, sedimentation velocity at pH 6.0
59400
wild-type, dimer, sedimentation velocity at pH 6.0
87500
minor form, gel filtration