2.7.4.2: phosphomevalonate kinase

This is an abbreviated version!
For detailed information about phosphomevalonate kinase, go to the full flat file.

Word Map on EC 2.7.4.2

2.7.4.2

isopentenyl

isoprenoids

diphosphomevalonate

5-diphosphate

mevalonate-5-pyrophosphate

pyrophosphomevalonate

2.7.1.36

cholesterogenesis

zellweger

nonsterol

medicine

Reaction

Synonyms

5-phosphomevalonate kinase, ATP:5-phosphomevalonate phosphotransferase, CcPMK, ERG8, GbPMK, kinase, phosphomevalonate (phosphorylating), mevalonate phosphate kinase, mevalonate-5-phosphate kinase, mevalonic acid phosphate kinase, More, phosphomevalonate kinase, phosphomevalonic kinase, PMK, PMVAK, PMVK, SSO2988

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.4 Phosphotransferases with a phosphate group as acceptor

2.7.4.2 phosphomevalonate kinase

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Results	in table
1	Activating Compound
6036	AA Sequence
2	Application
1	CAS Registry Number
18	Cloned(Commentary)
8	Cofactor
5	Crystallization (Commentary)
12	Disease/ Diagnostics
2	Expression
16	General Information
1	General Stability
29	Inhibitors
14	Ki Value [mM]
131	KM Value [mM]
7	Localization
41	Metals/Ions
16	Molecular Weight [Da]
23	Natural Substrates/ Products (Substrates)
42	Organism
1	Oxidation Stability
7	Pathway
8	PDB ID
9	pH Optimum
3	pH Range
1	pH Stability
2	pI Value
30	Protein Variants
16	Purification (Commentary)
7	Reaction
4	Reaction Type
41	Reference
26	Source Tissue
7	Specific Activity [micromol/min/mg]
6	Storage Stability
63	Substrates and Products (Substrate)
16	Subunits
44	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
2	Temperature Stability [°C]
4	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 2.7.4.2 - phosphomevalonate kinase

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128000

gel filtration

21000

1 * 21000, SDS-PAGE

22000

22500

22900

recombinant His-tagged wild-type enzyme, gel filtration

672134

24200

Homo sapiens

Q15126

1 * 24200, sequence calculation

672134

36200

Saccharolobus solfataricus

Q97UL6

x * 36200, calculated from sequence

722571

37747

Streptococcus pneumoniae

x * 37747, MALDI mass spectroscopy

645182

40500

Enterococcus faecalis

2 * 48000, SDS-PAGE, analytical ultracentrifugation, 2 * 40500, amino acid sequence

663336

48000

Enterococcus faecalis

2 * 48000, SDS-PAGE, analytical ultracentrifugation, 2 * 40500, amino acid sequence

663336

76000

Enterococcus faecalis

analytical ultracentrifugation

663336

81000

Enterococcus faecalis

calculated from amino acid sequence

663336