2.7.4.2: phosphomevalonate kinase

This is an abbreviated version!
For detailed information about phosphomevalonate kinase, go to the full flat file.

Reaction

Synonyms

5-phosphomevalonate kinase, ATP:5-phosphomevalonate phosphotransferase, CcPMK, ERG8, GbPMK, kinase, phosphomevalonate (phosphorylating), mevalonate phosphate kinase, mevalonate-5-phosphate kinase, mevalonic acid phosphate kinase, More, phosphomevalonate kinase, phosphomevalonic kinase, PMK, PMVAK, PMVK, SSO2988

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.4 Phosphotransferases with a phosphate group as acceptor

                2.7.4.2 phosphomevalonate kinase

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Results	in table
1	Activating Compound
6036	AA Sequence
2	Application
1	CAS Registry Number
18	Cloned(Commentary)
8	Cofactor
5	Crystallization (Commentary)
12	Disease/ Diagnostics
2	Expression
16	General Information
1	General Stability
29	Inhibitors
14	Ki Value [mM]
131	KM Value [mM]
7	Localization
41	Metals/Ions
16	Molecular Weight [Da]
23	Natural Substrates/ Products (Substrates)
42	Organism
1	Oxidation Stability
7	Pathway
8	PDB ID
9	pH Optimum
3	pH Range
1	pH Stability
2	pI Value
30	Protein Variants
16	Purification (Commentary)
7	Reaction
4	Reaction Type
41	Reference
26	Source Tissue
7	Specific Activity [micromol/min/mg]
6	Storage Stability
63	Substrates and Products (Substrate)
16	Subunits
44	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
2	Temperature Stability [°C]
4	Turnover Number [1/s]

Disease

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Disease on EC 2.7.4.2 - phosphomevalonate kinase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Cataract

Molecular functions of conserved aspects of the GHMP kinase family.

15544330

Deficiency Diseases

Farnesyl-diphosphate synthase is localized in peroxisomes.

8188698

galactokinase deficiency

Molecular functions of conserved aspects of the GHMP kinase family.

15544330

Galactosemias

Molecular functions of conserved aspects of the GHMP kinase family.

15544330

Porokeratosis

Disorder of the mevalonate pathway inhibits calcium-induced differentiation of keratinocytes.

28765912

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