2.7.4.14: UMP/CMP kinase

This is an abbreviated version!
For detailed information about UMP/CMP kinase, go to the full flat file.

Reaction

Synonyms

ATP:UMP-CMP phosphotransferase, CMP kinase, CMP/UMP kinase, CMPK, CMPK1, CMPK2, CTP:CMP phosphotransferase, cytidine monophosphate kinase, cytidine/uridine monophosphate kinase 2, cytidylate kinase, dCK, deoxycytidine kinase, EC 2.7.4.5, kinase, cytidylate (phosphorylating), More, MssA protein, nucleoside monophosphate kinase, P25, pyrimidine nucleoside monophosphate kinase, UCK, UMP-CMP kinase, UMP-CMP kinase 2, UMP-CMPK2, UMP/CMP kinase, UMP/CMP kinase 1, UMP/CMPK1, UMPK, uridine monophosphate/cytidine monophosphate kinase

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.4 Phosphotransferases with a phosphate group as acceptor

                2.7.4.14 UMP/CMP kinase

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Results	in table
13	Activating Compound
3225	AA Sequence
3	Application
1	CAS Registry Number
12	Cloned(Commentary)
7	Cofactor
1	Crystallization (Commentary)
112	Disease/ Diagnostics
1	Expression
9	General Information
8	General Stability
6	IC50 Value
45	Inhibitors
11	kcat/KM [mM/s]
10	Ki Value [mM]
132	KM Value [mM]
10	Localization
21	Metals/Ions
7	Molecular Weight [Da]
28	Natural Substrates/ Products (Substrates)
215	Organism
8	Pathway
29	PDB ID
7	pH Optimum
2	pH Range
3	pH Stability
1	pI Value
15	Protein Variants
13	Purification (Commentary)
6	Reaction
3	Reaction Type
40	Reference
1	Renatured (Commentary)
55	Source Tissue
9	Specific Activity [micromol/min/mg]
6	Storage Stability
188	Substrates and Products (Substrate)
6	Subunits
50	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
12	Temperature Stability [°C]
30	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 2.7.4.14 - UMP/CMP kinase

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SYSTEMATIC NAME

IUBMB Comments

ATP:CMP(UMP) phosphotransferase

This eukaryotic enzyme is a bifunctional enzyme that catalyses the phosphorylation of both CMP and UMP with similar efficiency. dCMP can also act as acceptor. Different from the monofunctional prokaryotic enzymes EC 2.7.4.25, (d)CMP kinase and EC 2.7.4.22, UMP kinase.