2.7.4.10: nucleoside-triphosphate-adenylate kinase
This is an abbreviated version!
For detailed information about nucleoside-triphosphate-adenylate kinase, go to the full flat file.
Word Map on EC 2.7.4.10
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2.7.4.10
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beef
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adp
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isozyme
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metastasis
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falciparum
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plasmodium
- 2.7.4.10
- beef
- adp
- isozyme
- metastasis
- falciparum
-
plasmodium
Reaction
Synonyms
adenylate kinase 3, adenylate kinase 4, AK3, AK4, CsAK3, GAK, GTP: AMP phosphotra nsferase, GTP:AMP phosphotransferase, guanosine triphosphate-adenylate kinase, kinase, nucleoside triphosphate-adenylate (phosphorylating), nucleoside triphosphate-adenosine monophosphate transphosphorylase, nucleoside triphosphate-adenylate kinase, ssozyme 3 of adenylate kinase
ECTree
2.7.4.10 nucleoside-triphosphate-adenylate kinaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 2.7.4.10 - nucleoside-triphosphate-adenylate kinase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
nucleoside triphosphate + AMP
nucleoside diphosphate + ADP
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involved in reaction sequence of substrate level phosphorylation
-
-
r
ATP + AMP
2 ADP
-
poor substrate, highly specific for AMP, phosphorylation at about 5% the rate of ITP
-
-
r
CTP + AMP
CDP + ADP
-
highly specific for AMP, phosphorylation at about 11% the rate of ITP
-
-
r
GTP + AMP
GDP + ADP
-
highly specific for AMP and ADP, in reverse reaction
via nucleotide-enzyme complex, no phosphorylated enzyme intermediate
r
GTP + AMP
GDP + ADP
-
phosphorylation at about 90% the rate of ITP
via nucleotide-enzyme complex, no phosphorylated enzyme intermediate
r
ITP + AMP
IDP + ADP
-
best substrate
via nucleotide-enzyme complex, no phosphorylated enzyme intermediate
r
ITP + AMP
IDP + ADP
-
highly specific for AMP and ADP in reverse reaction
via nucleotide-enzyme complex, no phosphorylated enzyme intermediate
r
ITP + AMP
IDP + ADP
-
no acceptor substrates are 3'-GMP
via nucleotide-enzyme complex, no phosphorylated enzyme intermediate
r
ITP + AMP
IDP + ADP
-
not: IMP, CMP, UMP
via nucleotide-enzyme complex, no phosphorylated enzyme intermediate
r
UTP + AMP
UDP + ADP
-
highly specific for AMP, phosphorylation at about 19% the rate of ITP
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-
r
additional information
?
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Q964H2
GTP + GMP/CMP/UMP activity below 1%, ATP + AMP activity below 1%
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-
?
additional information
?
-
-
GTP + GMP/CMP/UMP activity below 1%, ATP + AMP activity below 1%
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-
?
additional information
?
-
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the enzyme does not accept ATP as a substrate
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-
?
additional information
?
-
-
ATP + AMP no significant formation of ADP
-
-
?
