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2.7.3.2: creatine kinase

This is an abbreviated version!
For detailed information about creatine kinase, go to the full flat file.

Word Map on EC 2.7.3.2

Reaction

ATP
+
Creatine
=
ADP
 +
phosphocreatine

Synonyms

adenosine triphosphate-creatine transphosphorylase, adenosine-5'-triphosphate: creatine phosphotransferase, ATP-creatine transphosphorylase, ATP: creatine N-phosphotransferase, ATP:creatine phosphotransferase, B-type creatine kinase, BB-CK, BB-type creatine kinase, BCK, brain creatine kinase, brain type creatine kinase, brain-type CK, brain-type creatine kinase, CK, CK MM, CK-B, CK-BB, CK-MB, CK-MM, ckb, CKM, CKMB, CKMBI, CKMiMi, creatine kinase, creatine kinase B, creatine kinase M-type, creatine kinase MB, creatine kinase muscle type, creatine kinase-MB, creatine N-phosphotransferase, creatine phosphokinase, creatine phosphotransferase, creatinine kinase, creatinine kinase MB, hBBCK, hMMCK, kinase, creatine (phosphorylating), M-CK, M1-CK, MB-CK, MCK, Mi-CK, MiMi-CK, mit-CK, mitochondrial creatine kinase, MM-CK, MM-type creatine kinase, More, MtCK, muscle creatine kinase, muscle type creatine kinase, muscle-type creatine kinase, phosphocreatine kinase, plasma creatine kinase, PSCKM, recombinant human brain-type creatine kinase, rHBCK, RM-CK, s-type CK, sarcomeric CK, sMiCK, sMtCK, u-type CK, ubiquitous CK, ubiquitous MtCK, uMiCK, uMtCK, zMMCK

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.3 Phosphotransferases with a nitrogenous group as acceptor
                2.7.3.2 creatine kinase

Specific Activity

Specific Activity on EC 2.7.3.2 - creatine kinase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
148
mutant V72A, 25°C
15
-
synthesis of phosphocreatine
181
purified native octameric enzyme, pH and temperature not specified in the publication
2.99
-
crude homogenate
205.1
-
after 68.6fold purification
206
-
purified cytosolic isozyme
210
-
oxidized form of creatine kinase
22
-
mutant Trp to Phe
240
-
purified mitochondrial isozyme
245.5
-
wild-type enzyme
246
-
wild-type
250
-
30°C, pH 7.0
256
mutant C74M, 25°C
258
mutant C74L, 25°C
26
-
mutant Trp to Asn
26.8
-
mutant Tyr to Asn
263
mutant V75A, 25°C
266
mutant C74S, 25°C
272
mutant A76G, 25°C
274.9
-
reduced form of creatine kinase
278
mutant C74A, 25°C
28.8
-
mutant Tyr to His
29.6
-
mutant Trp to Cys
31.8
-
wild-type
32
-
mutant Trp to His
345
-
isoform CK1, pH 6.7
36.4
-
mutant Trp to Tyr
410
-
30°C
43.48
-
enzyme from embryonic stem cell-derived cardiomyocytes, pH 6.5, 37°C
43.7
-
mutant W264C
46.5
mutant L115D
49.5
-
synthesis of ATP
50.25
-
enzyme from neonatal cardiomyocytes, pH 6.5, 37°C
511
-
isoform CK2, pH 6.7
62.3
-
mutant W264Y
70.2
-
wild-type
71.2
-
mutant Tyr to Trp
8208
mutant G73A, 25°C
94.4
mutant L121D
additional information