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2.7.2.8: acetylglutamate kinase

This is an abbreviated version!
For detailed information about acetylglutamate kinase, go to the full flat file.

Word Map on EC 2.7.2.8

Reaction

ATP
+
N-acetyl-L-glutamate
=
ADP
 +
N-acetyl-L-glutamyl 5-phosphate

Synonyms

acetylglutamate kinase, acetylglutamate phosphokinase, amino-acid acetyltransferase, argB, CcNAGK, EcNAGK, GRMZM2G132777, kinase, acetylglutamate (phosphorylating), mmNAGS/K, N-acetyl glutamate kinase, N-acetyl-glutamate 5-phosphotransferase, N-acetyl-L-glutamate 5-phosphotransferase, N-acetyl-L-glutamate kinase, N-acetyl-L-glutamate synthase/kinase, N-acetylglutamate 5-phosphotransferase, N-acetylglutamate kinase, N-acetylglutamate phosphokinase, N-acetylglutamate-5-phosphotransferase, N-acetylglutamic 5-phosphotransferase, NagK, NAGK1, NAGS-K, SYPA5-5 N-acetylglutamate kinase, xcNAGS/K, yNAGK

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.2 Phosphotransferases with a carboxy group as acceptor
                2.7.2.8 acetylglutamate kinase

Specific Activity

Specific Activity on EC 2.7.2.8 - acetylglutamate kinase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.0008
-
pH 8.0, 70°C, activity in cell culture in growth medium with 0.2% yeast extract
0.003
-
pH 8.0, 70°C, activity in cell culture in minimal growth medium with 20 mM glucose and 5 mM NH4+
0.47
purified mutant K364H enzyme, pH 8.5, 30°C
0.54
-
pH 7.4, 37°C
0.62
-
wild type enzyme, at pH 8.0 and 37°C
0.77
-
mutant enzyme R209A, at pH 8.0 and 37°C
0.79
-
mutant enzyme H268N, at pH 8.0 and 37°C
1.66
purified mutant R394K enzyme, pH 8.5, 30°C
12
without PII protein
13.3
-
pH 7.5, complex of enzyme and PII protein
130
-
37°C, pH 7.5
20.1
-
pH 7.4, 37°C
24
with PII protein
3.11
purified mutant N399Q enzyme, pH 8.5, 30°C
3.3
-
pH 7.5, free enzyme
39.87
purified mutant S387A enzyme, pH 8.5, 30°C
4.97
purified mutant S387A enzyme, pH 8.5, 30°C
44.05
purified recominant wild-type enzyme, pH 8.5, 30°C
45
-
37°C, pH 7.5
6.81
purified recominant wild-type enzyme, pH 8.5, 30°C
677
-
80°C, pH 7.5
additional information