2.7.2.4: aspartate kinase

This is an abbreviated version!
For detailed information about aspartate kinase, go to the full flat file.

Reaction

Synonyms

AK, AK II, AK III, AK-HSDH, AK-HSDH I, AK-HSDH1, AK-HSDH2, AK-HseDH, AK-R7, AK-ts31d, AK1, AK2, AK3, AKbeta, AKII, AKIII, AKsyn, Ask, ASK1, ASK2, Ask_Ect, Ask_LysC, Asp kinase-homoserine dehydrogenase, aspartate kinase, aspartate kinase (phosphorylating), aspartate kinase 1, aspartate kinase 2, aspartate kinase 3, aspartate kinase beta, aspartate kinase I, aspartate kinase II, aspartate kinase III, aspartic kinase, aspartokinase, aspartokinase 1-homoserine dehydrogenase 1, aspartokinase 2, aspartokinase 3, aspartokinase I, aspartokinase II, aspartokinase III, aspartokinase-homoserine dehydrogenase, beta-aspartokinase, bifunctional aspartate kinase-homoserine dehydrogenase, BT, BTT, CgAK, dap-aspartokinase, HOM3 product, HOM3-R7 product, HOM3-ts31d product, HseDH, LT-aspartokinase, lysC, lysine-sensitive aspartokinase 3, More, MtbAKbeta, nspJ, Thr-sensitive aspartate kinase, thrA, thrA1, thrA2, TM_0547, XbAK

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.2 Phosphotransferases with a carboxy group as acceptor

                2.7.2.4 aspartate kinase

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Results	in table
27	Activating Compound
56694	AA Sequence
16	Application
1	CAS Registry Number
57	Cloned(Commentary)
11	Cofactor
14	Crystallization (Commentary)
1	Expression
32	General Information
9	General Stability
15	IC50 Value
196	Inhibitors
12	kcat/KM [mM/s]
29	Ki Value [mM]
206	KM Value [mM]
7	Localization
52	Metals/Ions
142	Molecular Weight [Da]
107	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
375	Organism
23	Pathway
96	PDB ID
23	pH Optimum
7	pH Range
6	pH Stability
3	pI Value
159	Protein Variants
70	Purification (Commentary)
2	Reaction
11	Reaction Type
149	Reference
1	Renatured (Commentary)
19	Source Tissue
54	Specific Activity [micromol/min/mg]
22	Storage Stability
174	Substrates and Products (Substrate)
75	Subunits
201	Synonyms
1	Systematic Name
19	Temperature Optimum [°C]
6	Temperature Range [°C]
25	Temperature Stability [°C]
71	Turnover Number [1/s]

Renatured

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Renatured on EC 2.7.2.4 - aspartate kinase

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RENATURED/Commentary

ORGANISM

UNIPROT

LITERATURE

when renatured after treatment with 6.0 M guanidine hydrochloride 80 to 90% of the original activity regained, renaturation of isolated alpha subunits leads to a lower recovery of activity, 65%, which is increased by about 30% in presence of an equivalent amount of beta subunit

Bacillus subtilis

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642319