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2.7.2.3: phosphoglycerate kinase

This is an abbreviated version!
For detailed information about phosphoglycerate kinase, go to the full flat file.

Word Map on EC 2.7.2.3

Reaction

ATP
+
3-phospho-D-glycerate
=
ADP
 +
3-phospho-D-glyceroyl phosphate

Synonyms

3-PGK, 3-phosphoglycerate 1-phosphotransferase, 3-phosphoglycerate kinase, 3-phosphoglycerate phosphokinase, 3-phosphoglyceric acid kinase, 3-phosphoglyceric acid phosphokinase, 3-phosphoglyceric kinase, AbPGK, ATP-3-phospho-D-glycerate-1-phosphotransferase, ATP:3-phospho-D-glycerate 1-phosphotransferase, ATP:D-3-phosphoglycerate 1-phosphotransferase, chl-PGK, glycerate 3-phosphate kinase, glycerophosphate kinase, HacPGK1, HacPGK2, HapPGK, hPGK, HsPGK, human 3-phosphoglycerate kinase, kinase (phosphorylating), phosphoglycerate, Mfer_0156, OsPGK2, P-glycerate kinase, PAS-PGK, PfPGK, PGK, PGK 1, PGK-1, PGK-2, pgk-B, PGK1, PGK2, Pgk3, Pgk5, PGKA, PGKase-1, PGKB, PGKC, pgkp1, pgkp2, phosphoglycerate kinase, phosphoglycerate kinase 1, phosphoglycerate kinase 2, phosphoglycerate kinase B, phosphoglycerate kinase-1, phosphoglyceric acid kinase, phosphoglyceric kinase, phosphoglycerokinase, PwPGK, SjPGK, SSO0527, testis-specific phosphoglycerate kinase 2, TRSC58_02767, X chromosome-linked phosphoglycerate kinase-1

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.2 Phosphotransferases with a carboxy group as acceptor
                2.7.2.3 phosphoglycerate kinase

KI Value

KI Value on EC 2.7.2.3 - phosphoglycerate kinase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1.44 - 1.5
1,3-bis(difluoro)-1,3-diphospho-2-dihydroxypropane
-
pH 7.5, 25°C
3.25 - 3.3
1,4-bis(difluoro)-1,4-diphospho-diethylether
-
pH 7.5, 25°C
0.56
1,4-Bisphosphonobutane
-
pH 8.5, 27°C
1.19 - 26
1,5-Bisphosphonopentane
0.109
1-beta-D-arabinofuranosylcytosine
-
pH 7.5
0.087
2',2'-difluorodeoxycytidine
-
pH 7.5
0.12
2',3'-dideoxy-2',3'-didehydro-beta-L(-)-5-fluorodeoxycytidine
-
pH 7.5
0.065
2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil
-
pH 7.5
0.35 - 3.8
2,3-diphosphoglycerate
0.1 - 0.15
2-(p-Sulfophenylazo)-1,8-dihydroxy-3,6-naphthalene disulfonic acid
0.065 - 0.075
2-Hydroxy-3,5-diiodobenzoate
0.06
2-Hydroxy-5-iodobenzoate
-
versus 3-phospho-D-glycerate, pH 7.8, 25°C
0.084
2-Oxo-1,4-bisphosphonobutane
-
pH 8.5, 27°C
0.2
2-Oxo-1,5-bisphosphonopentane
-
pH 8.5, 27°C
4
2-Phosphoglycolate
-
pH 7.5, 20°C, versus 3-phospho-D-glycerate
3.5
4-Phosphonobutyronitrile
-
pH 8.5, 27°C
0.08 - 1.14
ADP
0.17 - 0.22
ADP3-
0.03539
albendazole
at pH 8.5 and 25°C
1.5 - 2
AMP
1.5
AMP2-
-
pH 7.8, 25°C
0.1 - 1.3
ATP
0.25
beta-L-2',3'-dideoxy-3'-thiacytidine
-
pH 7.5
0.00188
clorsulon
at pH 8.5 and 25°C
-
0.045
D-2',3'-dideoxycytidine
-
pH 7.5
0.035
D-MgADP-
-
-
0.09 - 1.9
diphosphate
9.6
Glycerol 2-phosphate
-
pH 7.5, 20°C, versus 3-phospho-D-glycerate
0.7
glycerol 3-phosphate
-
pH 7.5, 20°C, versus 3-phospho-D-glycerate
1.28
Hexametaphosphate
-
pH 7.5, versus 3-phospho-D-glycerate
23 - 25
hydroxyethylidene bisphosphonic acid
0.125
L-2',3'-dideoxycytidine
-
pH 7.5
0.063
L-MgADP-
-
-
0.58
Mg-beta,gamma-imido-adenosine-5'-triphosphate
pH 7.5, 20°C
1.21
Mg-beta,gamma-methylene-adenosine-5'-triphosphate
pH 7.5, 20°C
0.039
MgADP-
pH 7.5, 20°C
5.5
Naphthalene-1,3,6-trisulfonic acid
-
pH 7.5, versus 3-phospho-D-glycerate
8.3
phosphate
-
pH 7.5, 20°C, versus 3-phospho-D-glycerate
0.009 - 0.011
salicylate
14
sulfate
-
pH 7.5, 20°C, versus 3-phospho-D-glycerate
0.0101 - 0.16
suramin
0.45
Zn2+
additional information
additional information
-