2.7.2.15: propionate kinase
This is an abbreviated version!
For detailed information about propionate kinase, go to the full flat file.
Word Map on EC 2.7.2.15
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2.7.2.15
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l-threonine
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typhimurium
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propionyl-coa
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propionyl
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non-oxidatively
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2-ketobutyrate
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in-line
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3-hydroxypropionic
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propionaldehyde
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reuteri
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1,3-propanediol
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3-hydroxypropionaldehyde
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thermophila
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nucleotide-bound
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methylcitrate
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formate-lyase
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methanosarcina
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phosphotransacetylase
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biobased
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biotechnology
- 2.7.2.15
- l-threonine
- typhimurium
- propionyl-coa
-
propionyl
-
non-oxidatively
- 2-ketobutyrate
-
in-line
-
3-hydroxypropionic
- propionaldehyde
- reuteri
- 1,3-propanediol
- 3-hydroxypropionaldehyde
- thermophila
-
nucleotide-bound
-
methylcitrate
- formate-lyase
-
methanosarcina
- phosphotransacetylase
-
biobased
- biotechnology
Reaction
Synonyms
ackA, PduW, propionate kinase II, propionate/acetate kinase, TdcD
ECTree
2.7.2.15 propionate kinaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 2.7.2.15 - propionate kinase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
ATP + acetate
ADP + acetyl phosphate
-
-
-
r
ATP + butyrate
ADP + butanoyl phosphate
-
-
-
r
CTP + propanoate
CDP + propanoyl phosphate
-
-
-
r
GTP + propanoate
GDP + propanoyl phosphate
-
-
-
r
UTP + propanoate
UDP + propanoyl phosphate
-
-
-
r
acetate + ATP
acetyl phosphate + ADP
-
-
-
-
?
ATP + propanoate
ADP + propanoyl phosphate
-
-
-
r
propionate + ATP
propionyl phosphate + ADP
-
-
-
-
?
additional information
?
-
-
TdcD has Ap4A synthetic activity in the presence of ATP
-
-
?
additional information
?
-
enzyme binding of nucleotide mainly involves hydrophobic interactions with the base moiety and can account for the broad biochemical specificity observed between the enzyme and nucleotides, modeling. Residue Ala88 is an important residue involved in determining the rate of catalysis with short-chain fatty acid substrates. No activity with with several closely related analogues such as formate, isobutyrate, 2-oxobutyrate, malic acid, citrate, isocitric acid, oxaloacetate, succinate and 2-oxoglutarate, and also no activit with short-chain alcohols methanol, ethanol, propanol, and butanol, and aldehydes acetaldehyde and propionaldehyde. An ethylene glycol molecule bound sufficiently close to the gamma-phosphate in StTdcD complexes with triphosphate nucleotides supports direct in-line phosphoryl transfer
-
-
?
additional information
?
-
-
enzyme binding of nucleotide mainly involves hydrophobic interactions with the base moiety and can account for the broad biochemical specificity observed between the enzyme and nucleotides, modeling. Residue Ala88 is an important residue involved in determining the rate of catalysis with short-chain fatty acid substrates. No activity with with several closely related analogues such as formate, isobutyrate, 2-oxobutyrate, malic acid, citrate, isocitric acid, oxaloacetate, succinate and 2-oxoglutarate, and also no activit with short-chain alcohols methanol, ethanol, propanol, and butanol, and aldehydes acetaldehyde and propionaldehyde. An ethylene glycol molecule bound sufficiently close to the gamma-phosphate in StTdcD complexes with triphosphate nucleotides supports direct in-line phosphoryl transfer
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-
?
