2.7.2.11: glutamate 5-kinase

This is an abbreviated version!
For detailed information about glutamate 5-kinase, go to the full flat file.

Word Map on EC 2.7.2.11

2.7.2.11

proba

1-pyrroline-5-carboxylate

l-proline

osmotolerance

delta1-pyrroline-5-carboxylate

osmoprotection

gpr

catharanthus

uprooted

biotechnology

Reaction

Synonyms

ATP-L-glutamate 5-phosphotransferase, ATP:gamma-L-glutamate phosphotransferase, G5K, gamma-GK, gamma-glutamate kinase, gamma-glutamyl kinase, gamma-glutamylphosphate kinase, GK, GKA, glutamate kinase, glutamate-5-kinase, GPK, kinase (phosphorylating), glutamate, kinase, glutamate (phosphorylating), PRO1, proB, scGK

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.2 Phosphotransferases with a carboxy group as acceptor

2.7.2.11 glutamate 5-kinase

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Results	in table
6	Activating Compound
34385	AA Sequence
6	Application
1	CAS Registry Number
16	Cloned(Commentary)
2	Cofactor
2	Crystallization (Commentary)
11	General Information
40	IC50 Value
53	Inhibitors
2	kcat/KM [mM/s]
15	Ki Value [mM]
20	KM Value [mM]
1	Localization
12	Metals/Ions
12	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
38	Organism
12	Pathway
52	PDB ID
6	pH Optimum
2	pH Range
1	pH Stability
61	Protein Variants
15	Purification (Commentary)
1	Reaction
1	Reaction Type
34	Reference
8	Source Tissue
11	Specific Activity [micromol/min/mg]
2	Storage Stability
51	Substrates and Products (Substrate)
11	Subunits
34	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
2	Temperature Stability [°C]
2	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 2.7.2.11 - glutamate 5-kinase

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0.49

3,4-dehydro-L-proline

Leishmania donovani

A0A0R6Y3I5

at pH 7.4 and 25Â°C

761064

1.8

L-4-thioproline

Leishmania donovani

A0A0R6Y3I5

at pH 7.4 and 25Â°C

761064

0.73

L-azetidine-2-carboxylic acid

Leishmania donovani

A0A0R6Y3I5

at pH 7.4 and 25Â°C

761064

0.08

L-Pro

Triticum aestivum

IC50: 0.08 mM, at room temperature. At low temperatures the inhibition switches over into allosteric activation and the biosynthesis of proline is started

642205

0.011 - 840

L-proline

36 entries