2.7.1.82: ethanolamine kinase
This is an abbreviated version!
For detailed information about ethanolamine kinase, go to the full flat file.
Word Map on EC 2.7.1.82
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2.7.1.82
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choline
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phosphatidylethanolamine
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phosphoethanolamine
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cdp-ethanolamine
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phosphocholine
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kennedy
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ptdetn
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cdp-choline
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setbp1
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medicine
- 2.7.1.82
- choline
- phosphatidylethanolamine
- phosphoethanolamine
- cdp-ethanolamine
- phosphocholine
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kennedy
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ptdetn
- cdp-choline
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setbp1
- medicine
Reaction
Synonyms
CEK4, choline/ethanolamine kinase, EKI, EKI1, ethanolamine kinase, ethanolamine kinase 1, ethanolamine kinase 2, ethanolamine phosphokinase, Etn kinase, EtnK, ETNK1, Etnk2, kinase, ethanolamine (phosphorylating), More, PfEK, Treki1
ECTree
2.7.1.82 ethanolamine kinaseAdvanced search results
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results (Engineering
Engineering on EC 2.7.1.82 - ethanolamine kinase
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PROTEIN VARIANTS 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
D816V
naturally occuring mutation involved in adult systemic mastocytosis, chronic myelomonocytic leukemia, or eosinophilia
G245A
naturally occuring mutation involved in adult systemic mastocytosis,with chronic myelomonocytic leukemia and/or eosinophilia, inactive mutant
N244K
naturally occuring mutation involved in adult systemic mastocytosis, with chronic myelomonocytic leukemia and/or eosinophilia, inactive mutant
N244S
naturally occuring mutation involved in adult systemic mastocytosis, with chronic myelomonocytic leukemia and/or eosinophilia, inactive mutant
N244T
naturally occuring mutation involved in adult systemic mastocytosis, with chronic myelomonocytic leukemia and/or eosinophilia, inactive mutant
additional information
additional information
construction of CEK4 knockout mutant, the CEK4 knockout causes embryonic lethality, and developmental arrest after the heart stage, with no defect in the pollen
additional information
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easily shocked mutation, significantly reduced levels of O-phosphoethanolamine and phosphatidylserine
additional information
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targeted disruption of Eki2 gene. No abnormalities in deficient mice with regard to embryonic and adult testis morphology, differentiation, function or fertility, and no significant differences in litter size, pup mortality rates or distribution of the sexes among the offspring compared with wild-type
additional information
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eki1Delta, main enzyme responsible for phosphoethanolamine synthesis eki1Delta cki1Delta, no residual enzymic activity
additional information
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targeted deletion of gene Treki1 by DNA insertion, Protoplast preparation and DNA-mediated transformation
additional information
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targeted deletion of gene Treki1 by DNA insertion, Protoplast preparation and DNA-mediated transformation
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additional information
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down-regulation of the expression of ethanolamine kinase and ethanolamine-phosphate cytidylyltransferase by RNAi results in inhibition of phosphatidylethanolamine synthesis in procyclic forms and, concomitantly, in a block in glycosylphosphatidylinositol attachment to procyclins and ethanolamine-phosphoglycerol modification of eukaryotic elongation factor 1A
