2.7.1.76: 2'-deoxyadenosine kinase

This is an abbreviated version!
For detailed information about 2'-deoxyadenosine kinase, go to the full flat file.

Word Map on EC 2.7.1.76

2.7.1.76

deaminase

deoxynucleoside

thymidine

acidophilus

5'-nucleotidase

hypoxanthine-guanine

ecto-5\'-nucleotidase

9-beta-d-arabinofuranosyladenine

mycoides

deoxycoformycin

2.7.1.20

heterotropic

medicine

Reaction

Synonyms

dAdo/dCyd kinase, dAK, dCK, dCyd kinase/dAdo kinase I, deoxyadenosine kinase, deoxycytidine kinase/deoxyadenosine kinase, dCK/dAK, deoxyguanosine kinase/deoxyadenosine kinase, dGK/dAK, dGuo kinase/dAdo kinase II, kinase, deoxyadenosine (phosphorylating), More, purine-deoxyribonucleoside kinase

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.76 2'-deoxyadenosine kinase

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Results	in table
7	Activating Compound
492	AA Sequence
1	Application
1	CAS Registry Number
7	Cloned(Commentary)
15	Cofactor
3	Crystallization (Commentary)
5	General Stability
29	Inhibitors
8	Ki Value [mM]
50	KM Value [mM]
3	Localization
11	Metals/Ions
10	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
45	Organism
5	Pathway
2	PDB ID
4	pH Optimum
2	pH Range
1	pH Stability
14	Protein Variants
11	Purification (Commentary)
2	Reaction
1	Reaction Type
37	Reference
22	Source Tissue
10	Specific Activity [micromol/min/mg]
4	Storage Stability
147	Substrates and Products (Substrate)
10	Subunits
27	Synonyms
1	Systematic Name
9	Temperature Optimum [°C]
1	Temperature Range [°C]
8	Temperature Stability [°C]
19	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 2.7.1.76 - 2'-deoxyadenosine kinase

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0.0000045

Solanum tuberosum

in 30 mM HEPES-NaOH buffer (pH 7.6), 10 mM MgCl2, 1 mM DTT, 3.75 mM ATP and 0.055 mM deoxyadenosine

676722

0.007

Homo sapiens

purified recombinant enzyme, substrates deoxycytidine and ATP

660855

0.027

Homo sapiens

substrate 2'-deoxycytidine and ATP

0.06

substrate ribavarin

0.073

0.43

purified recombinant enzyme, substrates deoxyadenosine and ATP

660855

0.54

Homo sapiens

substrate 2'-deoxyadenosine and ATP

662985

2.3

Bacillus subtilis

dAdo/dCyd kinase in crude recombinant Escherichia coli cell extract, substrate 2'-deoxyadenosine or 2'-deoxycytidine

640561

additional information

2 entries