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2.7.1.76: 2'-deoxyadenosine kinase

This is an abbreviated version!
For detailed information about 2'-deoxyadenosine kinase, go to the full flat file.

Word Map on EC 2.7.1.76

Reaction

ATP
+
2'-deoxyadenosine
=
ADP
+
dAMP

Synonyms

dAdo/dCyd kinase, dAK, dCK, dCyd kinase/dAdo kinase I, deoxyadenosine kinase, deoxycytidine kinase/deoxyadenosine kinase, dCK/dAK, deoxyguanosine kinase/deoxyadenosine kinase, dGK/dAK, dGuo kinase/dAdo kinase II, kinase, deoxyadenosine (phosphorylating), More, purine-deoxyribonucleoside kinase

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.76 2'-deoxyadenosine kinase

Cofactor

Cofactor on EC 2.7.1.76 - 2'-deoxyadenosine kinase

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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2'-deoxyadenosine-3'-fluoro-3'-triphosphate
-
62% of the activity with ATP and deoxycytidine, 1.5% of the activity with ATP and deoxyadenosine
2'-deoxyadenosine-3'-fluoroara-3'-triphosphate
-
59% of the activity with ATP and deoxycytidine, 1% of the activity with ATP and deoxyadenosine
2'-deoxyadenosine-3'-triphosphate
-
73% of the activity with ATP and deoxycytidine, 6% of the activity with ATP and deoxyadenosine
3'-deoxyadenosine-2'-triphosphate
-
97% of the activity with ATP and deoxycytidine, 60% of the activity with ATP and deoxyadenosine
3'-deoxyadenosine-3'-fluoro-2'-triphosphate
-
66% of the activity with ATP and deoxycytidine, 4% of the activity with ATP and deoxyadenosine
3'-deoxyadenosine-3'-fluoroxylo-2'-triphosphate
-
62% of the activity with ATP and deoxycytidine, 4% of the activity with ATP and deoxyadenosine
additional information
-
triphosphate is active with 2'-deoxycytidine, 40% of the activity with ATP, not with 2'-deoxyadenosine, no activity with diphosphate as phosphate donor
-