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2.7.1.71: shikimate kinase

This is an abbreviated version!
For detailed information about shikimate kinase, go to the full flat file.

Word Map on EC 2.7.1.71

Reaction

ATP
+
shikimate
=
ADP
 +
3-phosphoshikimate

Synonyms

adenosine triphosphate: shikimate-3-phosphotransferase, AroK, AroL, AtSK1, AtSK2, kinase (phosphorylating), shikimate, kinase, shikimate (phosphorylating), MtSK, OsSK1, OsSK2, OsSK3, Rv2539c, shikimate kinase II, shikimate kinase-like 1, SK I, SK II, SK1, SK2, SKI, SKII, SKL1, type I shikimate kinase, aroK-encoded, type II shikimate kinase

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.1 Phosphotransferases with an alcohol group as acceptor
                2.7.1.71 shikimate kinase

Temperature Stability

Temperature Stability on EC 2.7.1.71 - shikimate kinase

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
33
-
melting temperature
37
isozyme AtSK2 is highly unstable and becomes inactivated at 37°C, whereas the heat-induced isoform, AtSK1, is thermostable and fully active at 37°C
4 - 26
after 8 h of incubation, the enzyme maintains its maximal activity in a range from 4 to 20°C, while at 25 and 26°C, it drops to 70% and 60%, respectively. A further increase of two degrees leads to the loss of 70% of the maximal activity, and at 30°C the enzyme is practically inactive
40
-
midpoint of protein unfolding transition is 39.7°C for the wild-type enzyme, 39°C for the mutant enzyme C13S and 43.0°C for the wild-type enzyme K15M in absence of ligands
45
melting temperature