2.7.1.59: N-acetylglucosamine kinase

This is an abbreviated version!
For detailed information about N-acetylglucosamine kinase, go to the full flat file.

Reaction

Synonyms

2-acetylamino-2-deoxy-D-glucose kinase, acetylaminodeoxyglucokinase, acetylglucosamine kinase(phosphorylating), ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase, CaNag5p, GlcNAc kinase, GlcNAc-kinase, GNK, Hxk1, MurK, N-acetyl-D-glucosamine kinase, N-acetylglucosamine kinase, N-acetylmuramic acid/N-acetylglucosamine kinase, NAG5, NAGA kinase, NagK

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.59 N-acetylglucosamine kinase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
5	Activating Compound
4929	AA Sequence
1	Application
1	CAS Registry Number
15	Cloned(Commentary)
5	Cofactor
1	Crystallization (Commentary)
10	Disease/ Diagnostics
2	Expression
13	General Information
9	General Stability
39	Inhibitors
5	kcat/KM [mM/s]
5	Ki Value [mM]
50	KM Value [mM]
15	Localization
25	Metals/Ions
16	Molecular Weight [Da]
37	Natural Substrates/ Products (Substrates)
39	Organism
4	Pathway
34	PDB ID
9	pH Optimum
1	pH Range
3	pH Stability
13	Protein Variants
20	Purification (Commentary)
1	Reaction
1	Reaction Type
39	Reference
47	Source Tissue
17	Specific Activity [micromol/min/mg]
9	Storage Stability
87	Substrates and Products (Substrate)
9	Subunits
58	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
8	Temperature Stability [°C]
7	Turnover Number [1/s]

KM Value

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

KM Value on EC 2.7.1.59 - N-acetylglucosamine kinase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to KM Value Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.00014 - 1.82

ATP

14 entries

0.0011 - 600

D-glucose

8 entries

0.426 - 67

D-mannose

2 entries

0.00025

ITP

Escherichia coli

-

37°C, pH 7.8

641692

0.268

N-acetyl-D-galactosamine

Arabidopsis thaliana

-

at pH 7.5 and 25°C

738241

0.00005 - 1.33

N-acetyl-D-glucosamine

18 entries

0.95 - 1

N-acetyl-D-mannosamine

3 entries

additional information

additional information

Mus musculus

-

Km for both substrates tested for wild type and all mutant enzymes

641703

-

0.00014

ATP

Escherichia coli

-

37°C, pH 7.8

641692

0.1

ATP

Rattus norvegicus

-

enzyme from kidney with N-acetyl-D-glucosamine as substrate, 32°C, pH 7.5

641697

0.1

ATP

Rattus norvegicus

-

ATP in form of MgATP2-

641697

0.13

ATP

Rattus norvegicus

-

wild type enzyme, at pH 7.5 and 37°C

739071

0.15

ATP

Rattus norvegicus

-

mutant enzyme C143S, at pH 7.5 and 37°C

739071

0.152

ATP

Arabidopsis thaliana

-

at pH 7.5 and 25°C

738241

0.23

ATP

Rattus norvegicus

-

enzyme from liver with N-acetyl-D-glucosamine as substrate, 32°C, pH 7.5

641697

0.23

ATP

Rattus norvegicus

-

ATP in form of MgATP2-

641697

0.9

ATP

Escherichia coli

-

pH 7.8, 37°C

659055

1

ATP

Yarrowia lipolytica

-

at pH 7.5 and 30°C

739411

1.59

ATP

Rattus norvegicus

-

mutant enzyme N36A, at pH 7.5 and 37°C

739071

1.8

ATP

Homo sapiens

-

37°C, pH 8.0

641694

1.8

ATP

Sus scrofa

-

37°C, pH 9.0

641693, 641695

1.82

ATP

Candida albicans

-

30°C, pH 7.6

641696

0.0011

D-glucose

Streptococcus pyogenes

-

30°C, pH 7.4

641691

0.005

D-glucose

Escherichia coli

-

37°C, pH 7.8

641692

0.483

D-glucose

Candida albicans

-

37°C, pH 7.5

641702

37.2

D-glucose

Escherichia coli

-

pH 7.8, 37°C

659055

55.56

D-glucose

Arabidopsis thaliana

-

at pH 7.5 and 25°C

738241

135

D-glucose

Yarrowia lipolytica

-

at pH 7.5 and 30°C

739411

410

D-glucose

Rattus norvegicus

-

enzyme from kidney, 32°C, pH 7.5

641697

600

D-glucose

Rattus norvegicus

-

enzyme from liver, 32°C, pH 7.5

641697

0.426

D-mannose

Candida albicans

-

37°C, pH 7.5

641702

67

D-mannose

Yarrowia lipolytica

-

at pH 7.5 and 30°C

739411

0.00005

N-acetyl-D-glucosamine

Escherichia coli

-

37°C, pH 7.8

641692

0.00077

N-acetyl-D-glucosamine

Streptococcus pyogenes

-

30°C, pH 7.4

641691

0.04

N-acetyl-D-glucosamine

Rattus norvegicus

-

enzyme from kidney, 32°C, pH 7.5

641697

0.046

N-acetyl-D-glucosamine

Arabidopsis thaliana

-

at pH 7.5 and 25°C

738241

0.05

N-acetyl-D-glucosamine

Rattus norvegicus

-

37°C, pH 7.5

641700

0.06

N-acetyl-D-glucosamine

Rattus norvegicus

-

enzyme from liver, 32°C, pH 7.5

641697

0.089

N-acetyl-D-glucosamine

Homo sapiens

-

37°C, pH 7.5

246598

0.11

N-acetyl-D-glucosamine

Homo sapiens

-

37°C, pH 8.0

641694

0.127

N-acetyl-D-glucosamine

Clostridium acetobutylicum

-

pH 7.5, 37°C

722533

0.34

N-acetyl-D-glucosamine

Escherichia coli

-

pH 7.8, 37°C

659055

0.376

N-acetyl-D-glucosamine

Candida albicans

-

37°C, pH 7.5

641702

0.445

N-acetyl-D-glucosamine

Homo sapiens

-

37°C, pH 7.5

641702

0.5

N-acetyl-D-glucosamine

Yarrowia lipolytica

-

at pH 7.5 and 30°C

739411

0.78

N-acetyl-D-glucosamine

Rattus norvegicus

-

wild type enzyme, at pH 7.5 and 37°C

739071

0.86

N-acetyl-D-glucosamine

Rattus norvegicus

-

mutant enzyme C143S, at pH 7.5 and 37°C

739071

1.1

N-acetyl-D-glucosamine

Sus scrofa

-

37°C, pH 9.0

641693, 641695

1.17

N-acetyl-D-glucosamine

Rattus norvegicus

-

mutant enzyme N36A, at pH 7.5 and 37°C

739071

1.33

N-acetyl-D-glucosamine

Candida albicans

-

30°C, pH 7.6

641696

0.95

N-acetyl-D-mannosamine

Rattus norvegicus

-

enzyme from liver, 32°C, pH 7.5

641697

1

N-acetyl-D-mannosamine

Rattus norvegicus

-

37°C, pH 7.5

641700

1

N-acetyl-D-mannosamine

Rattus norvegicus

-

enzyme from kidney, 32°C, pH 7.5

641697