2.7.1.59: N-acetylglucosamine kinase

This is an abbreviated version!
For detailed information about N-acetylglucosamine kinase, go to the full flat file.

Word Map on EC 2.7.1.59

2.7.1.59

albicans

n-acetylmannosamine

hexokinases

glcnac-6-phosphate

glucosamine-6-phosphate

aminosugars

udp-n-acetylglucosamine

udp-glcnac

dynlrb1

n-acetylneuraminic

dynein

roadblock

mannac

2-epimerase

analysis

Reaction

Synonyms

2-acetylamino-2-deoxy-D-glucose kinase, acetylaminodeoxyglucokinase, acetylglucosamine kinase(phosphorylating), ATP:2-acetylamino-2-deoxy-D-glucose 6-phosphotransferase, CaNag5p, GlcNAc kinase, GlcNAc-kinase, GNK, Hxk1, MurK, N-acetyl-D-glucosamine kinase, N-acetylglucosamine kinase, N-acetylmuramic acid/N-acetylglucosamine kinase, NAG5, NAGA kinase, NagK

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.59 N-acetylglucosamine kinase

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Results	in table
5	Activating Compound
4929	AA Sequence
1	Application
1	CAS Registry Number
15	Cloned(Commentary)
5	Cofactor
1	Crystallization (Commentary)
10	Disease/ Diagnostics
2	Expression
13	General Information
9	General Stability
39	Inhibitors
5	kcat/KM [mM/s]
5	Ki Value [mM]
50	KM Value [mM]
15	Localization
25	Metals/Ions
16	Molecular Weight [Da]
37	Natural Substrates/ Products (Substrates)
39	Organism
4	Pathway
34	PDB ID
9	pH Optimum
1	pH Range
3	pH Stability
13	Protein Variants
20	Purification (Commentary)
1	Reaction
1	Reaction Type
39	Reference
47	Source Tissue
17	Specific Activity [micromol/min/mg]
9	Storage Stability
87	Substrates and Products (Substrate)
9	Subunits
58	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
8	Temperature Stability [°C]
7	Turnover Number [1/s]

General Stability

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General Stability on EC 2.7.1.59 - N-acetylglucosamine kinase

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ammonium sulfate partially stabilizes against temperature inactivation

Streptococcus pyogenes

641691

dialysis at 4°C for 17 h against 0.005 M Tris buffer, pH 7.6, 92% loss of activity, 33% loss of activity in presence of 0.1 M N-acetyl-D-glucosamine or glucose, stable in presence of 0.2 M or 2.5

Streptococcus pyogenes

641691

stable to dialysis

2 entries

substrate at 0.2 M stabilizes, unstable in absence of substrate at 4°C

Streptococcus pyogenes

641691

unstable to dialysis and gel filtration, 0.013 mM substrate protects against inactivation

Homo sapiens

641694

unstable to freezing and thawing, heat and low pH

2 entries