2.7.1.50: hydroxyethylthiazole kinase

This is an abbreviated version!
For detailed information about hydroxyethylthiazole kinase, go to the full flat file.

Word Map on EC 2.7.1.50

2.7.1.50

thiamin

pyrophosphate

monophosphate

salvage

hydroxymethylpyrimidine

pyrimidine

4-amino-5-hydroxymethyl-2-methylpyrimidine

2.7.1.35

tpp

protomers

pyrophosphorylase

octamer

2-methyl-4-amino-5-hydroxymethylpyrimidine

ribokinase

antimetabolite

Reaction

Synonyms

4-methyl-5-(beta-hydroxyethyl) thiazole kinase, 4-methyl-5-(beta-hydroxyethyl)thiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase , 4-methyl-5-hydroxyethylthiazole kinase, At3g24030, GRMZM2G094558, hydroxyethylthiazole kinase/thiamine-phosphate pyrophosphorylase, kinase, hydroxyethylthiazole (phosphorylating), More, SaThiM, TH kinase, THI6, thiazole kinase, ThiK, ThiM, THZ kinase

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.50 hydroxyethylthiazole kinase

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Results	in table
14495	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
2	Cofactor
5	Crystallization (Commentary)
13	General Information
2	Inhibitors
3	kcat/KM [mM/s]
1	Ki Value [mM]
6	KM Value [mM]
10	Metals/Ions
5	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
57	Organism
7	Pathway
74	PDB ID
2	pH Optimum
1	pH Range
1	Protein Variants
5	Purification (Commentary)
3	Reaction
1	Reaction Type
15	Reference
22	Specific Activity [micromol/min/mg]
1	Storage Stability
37	Substrates and Products (Substrate)
12	Subunits
36	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Stability [°C]
3	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 2.7.1.50 - hydroxyethylthiazole kinase

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ADP + 4-methyl-5-(2-hydroxyethyl)thiazole

AMP + 4-methyl-5-(2-phosphonooxyethyl)thiazole

Saccharomyces cerevisiae

3.4% of the activity with ATP

639720

ATP + 1,3,5-trimethyl-4-(2-hydroxyethyl)pyrazole

ADP + 2-(1,3,5-trimethyl-1H-pyrazol-4-yl)ethyl phosphate

2 entries

ATP + 2-methyl-3-(2-hydroxyethyl)imidazole

ADP + 2-(2-methyl-1H-imidazol-1-yl)ethyl phosphate

2 entries

ATP + 4-methyl-5-(2-hydroxyethyl)thiazole

ADP + 4-methyl-5-(2-phosphoethyl)thiazole

Bacillus subtilis

658936

ATP + 4-methyl-5-(2-hydroxyethyl)thiazole

ADP + 4-methyl-5-(2-phosphonooxyethyl)thiazole

11 entries

ATP + 4-methyl-5-(2-hydroxyethyl)thiazole

ADP + 4-methyl-5-(2-phosphooxyethyl)thiazole

2 entries

ATP + 5-(2-hydroxyethyl)-4-methylthiazole

ADP + 4-methyl-5-(2-phosphoethyl)-thiazole

Saccharomyces cerevisiae

639720

CTP + 4-methyl-5-(2-hydroxyethyl)thiazole

CDP + 4-methyl-5-(2-phosphonooxyethyl)thiazole

2 entries

dATP + 4-methyl-5-(2-hydroxyethyl)thiazole

dADP + 4-methyl-5-(2-phosphonooxyethyl)thiazole

2 entries

dCTP + 4-methyl-5-(2-hydroxyethyl)thiazole

dCDP + 4-methyl-5-(2-phosphonooxyethyl)thiazole

Escherichia coli

P76423

737878

dGTP + 4-methyl-5-(2-hydroxyethyl)thiazole

dGDP + 4-methyl-5-(2-phosphonooxyethyl)thiazole

Escherichia coli

P76423

737878

dUTP + 4-methyl-5-(2-hydroxyethyl)thiazole

dUDP + 4-methyl-5-(2-phosphonooxyethyl)thiazole

Escherichia coli

P76423

737878

GTP + 4-methyl-5-(2-hydroxyethyl)thiazole

GDP + 4-methyl-5-(2-phosphonooxyethyl)thiazole

2 entries

TTP + 4-methyl-5-(2-hydroxyethyl)thiazole

TDP + 4-methyl-5-(2-phosphonooxyethyl)thiazole

Escherichia coli

P76423

737878

UTP + 4-methyl-5-(2-hydroxyethyl)thiazole

UDP + 4-methyl-5-(2-phosphonooxyethyl)thiazole

2 entries

additional information

6 entries